7-(4-Chlorophenyl)-1,3-dimethyl-5,5-bis(trifluoromethyl)-8H-pyrimido[4,5-d]pyrimidine-2,4-dione is a synthetic organic compound characterized by its complex structure, which includes a pyrimidine core fused with a pyrimidine ring. This compound features multiple functional groups, including chlorophenyl and trifluoromethyl substituents, which contribute to its unique chemical properties. The presence of the trifluoromethyl groups enhances lipophilicity and can influence biological activity, making it of interest in pharmaceutical research. The compound is likely to exhibit significant stability due to the presence of the dione functional groups, which can participate in various chemical reactions. Its molecular structure suggests potential applications in medicinal chemistry, particularly in the development of novel therapeutic agents. Additionally, the compound's CAS number, 488097-06-9, allows for easy identification and retrieval of information in chemical databases. Overall, this substance exemplifies the intricate design often found in drug discovery, where specific modifications can lead to enhanced efficacy and selectivity in biological systems.

VU 0650991 is a non-competitive GLP-1 antagonist that is orally bioavailable and acts as a brain penetrant.

7-(4-chlorophenyl)-1,3-dimethyl-5,5-bis(trifluoromethyl)-8H-pyrimido[4,5-d]pyrimidine-2,4-dione

488097-06-9: 7-(4-Chlorophenyl)-1,3-dimethyl-5,5-bis(trifluoromethyl)-8H-pyrimido[4,5-d]pyrimidine-2,4-dione is a synthetic organic compound characterized by its complex structure, which includes a pyrimidine core fused with a pyrimidine ring. This compound features multiple functional groups, including chlorophenyl and trifluoromethyl substituents, which contribute to its unique chemical properties. The presence of the trifluoromethyl groups enhances lipophilicity and can influence biological activity, making it of interest in pharmaceutical research. The compound is likely to exhibit significant stability due to the presence of the dione functional groups, which can participate in various chemical reactions. Its molecular structure suggests potential applications in medicinal chemistry, particularly in the development of novel therapeutic agents. Additionally, the compound's CAS number, 488097-06-9, allows for easy identification and retrieval of information in chemical databases. Overall, this substance exemplifies the intricate design often found in drug discovery, where specific modifications can lead to enhanced efficacy and selectivity in biological systems.

GLP-1R Antagonist 1

GLP-1R Antagonist 1 is an orally active, CNS penetrant and non-competitive glucagon-like peptide 1 receptor (GLP-1R) antagonist (IC50: 650 nM).

Glucagon-like peptide-1 receptor (GLP-1R) antagonist

CAS 488097-06-9

7-(4-chlorophenyl)-1,3-dimethyl-5,5-bis(trifluoromethyl)-8H-pyrimido[4,5-d]pyrimidine-2,4-dione

GLP-1R Antagonist 1

Ref: 54-BUP01377

GLP-1R Antagonist 1

Ref: TM-T15387

VU 0650991

Ref: 3D-BV168185