CAS 492-39-7

Cathine

Description:

Cathine, also known as norpseudoephedrine, is a naturally occurring stimulant and a phenethylamine derivative. It is primarily found in the khat plant (Catha edulis), which is traditionally chewed for its stimulant effects. Cathine acts as a central nervous system stimulant, exhibiting effects similar to those of amphetamines, though it is generally considered to be less potent. The chemical structure of cathine includes a phenolic hydroxyl group and an amine group, contributing to its pharmacological activity. It is classified as a controlled substance in several countries due to its potential for abuse and dependence. Cathine is known to increase alertness, energy, and mood, but it may also lead to side effects such as increased heart rate, anxiety, and insomnia. Its use is often associated with the cultural practices surrounding khat chewing, particularly in East Africa and the Arabian Peninsula. Due to its stimulant properties, cathine has been studied for its potential therapeutic applications, although its use in medicine remains limited.

Formula: C₉H₁₃NO

InChI: InChI=1S/C9H13NO/c1-7(10)9(11)8-5-3-2-4-6-8/h2-7,9,11H,10H2,1H3/t7-,9+/m0/s1

InChI key: InChIKey=DLNKOYKMWOXYQA-IONNQARKSA-N

SMILES: [C@H]([C@H](C)N)(O)C1=CC=CC=C1

Synonyms:

• (+)-Pseudonorephedrin
• (+)-Pseudonorephedrine
• (1S)(2S)-Cathine
• (1S,2S)-(+)-Norpseudoephedrine
• (1S,2S)-2-Amino-1-phenyl-1-propanol
• (1S,2S)-2-amino-1-phenylpropan-1-ol
• (1S,2S)-Norephedrine
• (1S,2S)-Pseudonorephedrine
• (1S,2S)-threo-Norephedrine
• (αS)-α-[(1S)-1-Aminoethyl]benzenemethanol
• 2-(5-Ethylpyridin-2-Yl)Ethanol
• <span class="text-smallcaps">D</span>-(+)-Norpseudoephedrine
• <span class="text-smallcaps">D</span>-Norpseudoephedrin
• Benzenemethanol, α-(1-aminoethyl)-, [S-(R*,R*)]-
• Benzenemethanol, α-[(1S)-1-aminoethyl]-, (αS)-
• Benzyl alcohol, α-(1-aminoethyl)-, (+)-
• Cathin
• Fugoa-Depot
• Katine
• Norpseudoephedrine
• d-Norpseudoephedrine
• d-Pseudonorephedrine

Cathine

Controlled Product

CAS: 492-39-7

Applications (+)-Pseudo Norephedrine is an epimer of phenylpropanolamine and a metabolite of cathinone.
References Marrero-Ponce, Y., et al.: Bioorg. Med. Chem., 13, 2881 (2005), Rytting, E., et al.: J. Pharmacol. Exp. Ther., 312, 192 (2005), Krizevski, R., et al.: J. Ethnopharmacol., 114, 432 (2007),

Formula: C₉H₁₃NO

Color and Shape: Neat

Molecular weight: 151.21

Ref: TR-P839580