CAS 492-94-4

Furil

Description:

Furil, with the CAS number 492-94-4, is a chemical compound known for its use in various applications, particularly in the pharmaceutical and agricultural sectors. It is classified as a heterocyclic compound, specifically a furan derivative, which contributes to its unique chemical properties. Furil typically exhibits a yellow crystalline appearance and is soluble in organic solvents, making it useful in synthesis and formulation processes. The compound is known for its potential biological activity, including antimicrobial and anti-inflammatory properties, which have been explored in various studies. Additionally, Furil can participate in various chemical reactions due to its reactive functional groups, allowing for further derivatization and modification. Safety data indicates that, like many chemical substances, it should be handled with care, as it may pose health risks if ingested or improperly managed. Overall, Furil's distinctive characteristics and versatility make it a compound of interest in both research and industrial applications.

Formula: C₁₀H₆O₄

InChI: InChI=1S/C10H6O4/c11-9(7-3-1-5-13-7)10(12)8-4-2-6-14-8/h1-6H

InChI key: InChIKey=SXPUVBFQXJHYNS-UHFFFAOYSA-N

SMILES: C(C(=O)C1=CC=CO1)(=O)C2=CC=CO2

Synonyms:

• 1,2-Bis(2-furanyl)-1,2-ethanedione
• 1,2-Bis(2-furyl)-1,2-ethanedione
• 1,2-Bis(2-furyl)ethanedione
• 1,2-Bis(furan-2-yl)ethanedione
• 1,2-Di(2-furanyl)-1,2-ethanedione
• 1,2-Di(2-furyl)ethane-1,2-dione
• 1,2-Di(2-furyl)ethanedione
• 1,2-Di(Furan-2-Yl)Ethane-1,2-Dione
• 1,2-Di-2-furylethane-1,2-dione
• 1,2-Ethanedione, 1,2-di-2-furanyl-
• 2,2-Furil, 98%
• 2,2′-Furil
• Bipyromucyl
• Di-2-furanylethanedione
• Difuranylglyoxal
• Ethanedione, di-2-furanyl-
• Furil
• NSC 5561

Furil

CAS: 492-94-4

Formula: C₁₀H₆O₄

Purity: >98.0%(GC)

Color and Shape: White to Amber powder to crystal

Molecular weight: 190.15

Ref: 3B-F0078

2,2'-Furil, 98%

CAS: 492-94-4

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₀H₆O₄

Purity: 98%

Color and Shape: Crystals or powder or crystalline powder, Yellow

Molecular weight: 190.15

Ref: 02-A15386

Furil

CAS: 492-94-4

Formula: C₁₀H₆O₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 190.1522

Ref: IN-DA003QPJ

1,2-Di(2-furyl)ethane-1,2-dione

CAS: 492-94-4

1,2-Di(2-furyl)ethane-1,2-dione

Formula: C₁₀H₆O₄

Purity: 98%

Color and Shape: yellow powder

Molecular weight: 190.15g/mol

Ref: 54-OR30173

Furil

CAS: 492-94-4

Formula: C₁₀H₆O₄

Molecular weight: 190.15

Ref: 7W-GL5996

Furil

CAS: 492-94-4

Furil is a pharmaceutical preparation used for the treatment of metabolic disorders, such as hypertension and diabetes. Furil is an inhibitor of the enzyme acyl coenzyme A: diacylglycerol acyltransferase-2 (DGAT-2) which catalyses the formation of triacylglycerols from diacylglycerol and free fatty acids. Furil has been shown to have potent inhibitory activity against DGAT-2, with an IC50 value of 0.5 μM. Furil also inhibits the enzyme phosphodiesterase 4B (PDE4B), which plays a role in signal transduction and inflammation. Furil can be synthesized by reacting hydrogen chloride with 2-bromoacetophenone in a nonpolar solvent to form 2,4-dichlorobenzoyl chloride, followed by reaction with 3-furancarboxylic acid in methanol to produce furil. Furil

Formula: C₁₀H₆O₄

Purity: Min. 95%

Color and Shape: Beige Powder

Molecular weight: 190.15 g/mol

Ref: 3D-FF70260

1,2-bis(furan-2-yl)ethane-1,2-dione

CAS: 492-94-4

Formula: C₁₀H₆O₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 190.154

Ref: 10-F358195

α-Furil

Controlled Product

CAS: 492-94-4

Applications α-Furil is an important industrial chemical that is used as a building block for synthesis in the pharmaceutical industry. α-Furil is also part of a group of diketones that act as skin sensitizers.
References Roberts, D., et al.: Contact Dermatitis, 41, 14 (1999); Wang, L., et al.: Adv. Mat. Res., 554, 764 (2012)

Formula: C₁₀H₆O₄

Color and Shape: Neat

Molecular weight: 190.15

Ref: TR-F861500