CAS 4936-47-4
:Nifuratel
Description:
Nifuratel is a synthetic nitrofuran derivative primarily used for its antimicrobial properties. It exhibits broad-spectrum activity against various bacteria and protozoa, making it effective in treating infections, particularly in the urogenital tract. The compound is characterized by its nitro group, which contributes to its mechanism of action by interfering with microbial DNA synthesis. Nifuratel is typically administered in the form of oral tablets or topical formulations, and it is known for its relatively low toxicity profile compared to other antimicrobials. Additionally, it has anti-inflammatory properties, which can aid in alleviating symptoms associated with infections. The substance is soluble in organic solvents but has limited solubility in water, which can influence its bioavailability. As with any medication, potential side effects may include gastrointestinal disturbances or allergic reactions, and its use should be guided by a healthcare professional. Overall, Nifuratel represents a valuable option in the pharmacological arsenal against certain infectious diseases.
Formula:C10H11N3O5S
InChI:InChI=1S/C10H11N3O5S/c1-19-6-8-5-12(10(14)18-8)11-4-7-2-3-9(17-7)13(15)16/h2-4,8H,5-6H2,1H3
InChI key:InChIKey=SRQKTCXJCCHINN-UHFFFAOYSA-N
SMILES:N(=CC=1OC(N(=O)=O)=CC1)N2CC(CSC)OC2=O
Synonyms:- 2-Oxazolidinone, 5-[(methylthio)methyl]-3-[(5-nitrofurfurylidene)amino]-
- 2-Oxazolidinone, 5-[(methylthio)methyl]-3-[[(5-nitro-2-furanyl)methylene]amino]-
- 3-[(5-Nitro-2-furfurylidene)amino]-5-[(methylthio)methyl]-2-oxazolidinone
- 5-((Methylthio)Methyl)-3-((5-Nitrofurfurylidine)Amino)-2-Oxazolidinon
- 5-((Methylthio)Methyl)-3-((5-Nitrofurfurylidine)Amino)-2-Oxazolidinone
- 5-(Methylmercaptomethyl)-3-(5-nitro-2-furfurylidenamino)-2-oxazolidinone
- 5-(Methylthiomethyl)-3-(5-nitro-2-furfurylidenamino)oxazolidin-2-one
- 5-Methylthiomethyl-3-(5-Nitrofurfurylideneamino)-2-Oxazolidone
- 5-[(Methylthio)Methyl]-3-[[(5-Nitro-2-Furanyl)Methylene]Amino-]-2-Oxazo-Lidinone
- 5-[(Methylthio)methyl]-3-[(5-nitrofurfurylidene)amino]-2-oxazolidinone
- 5-[(Methylthio)methyl]-3-[[(5-nitro-2-furanyl)methylene]amino]-2-oxazolidinone
- 5-[(methylsulfanyl)methyl]-3-{[(1E)-(5-nitrofuran-2-yl)methylidene]amino}-1,3-oxazolidin-2-one
- 5-[(methylsulfanyl)methyl]-3-{[(1Z)-(5-nitrofuran-2-yl)methylidene]amino}-1,3-oxazolidin-2-one
- Inimur
- L’N-(5-Nitro-2-Furfurilidene)-3-Amino-5-Metilmercaptometil-2-Ossazolidinone
- Macmiror
- Magmilor
- Methylmercadone
- Nf 113
- Omnes
- Polmiror
- Sap 113
- See more synonyms
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Nifuratel
CAS:Formula:C10H11N3O5SPurity:>98.0%(HPLC)Color and Shape:White to Yellow to Green powder to crystalMolecular weight:285.27Nifuratel
CAS:Nifuratel (SAP 113) is a local antiprotozoal and antifungal agent that may also be given orally.Formula:C10H11N3O5SPurity:99.76% - 99.87%Color and Shape:Fresh Yellow Crystalline Or Yellow PowderMolecular weight:285.2765-(Methylsulfanylmethyl)-3-[(E)-(5-nitrofuran-2-yl)methylideneamino]-1,3-oxazolidin-2-one
CAS:5-(Methylsulfanylmethyl)-3-[(E)-(5-nitrofuran-2-yl)methylideneamino]-1,3-oxazolidin-2-oneFormula:C10H11N3O5SPurity:>98.0%Color and Shape:SolidMolecular weight:285.276445-[(Methylthio)methyl]-3-[[(5-nitro-2-furanyl)methylene]amino]-2-oxazolidinone
CAS:Formula:C10H11N3O5SPurity:99%Color and Shape:SolidMolecular weight:285.2764Nifuratel
CAS:Controlled ProductStability Hygroscopic
Applications Nifuratel is a drug used as an antibacterial, antifungal, antiprotozoal (Trichomonas). Nifuratel appears to have a broad antibacterial spectrum of action and is effective against Chlamydia trachomatis and Mycoplasma spp. as well as fungal infections from Candida spp.
References Nam, H., et al.: J. Microbiol., 45, 515 (2007), Costerton, W., et al.: J. Clin. Invest., 112, 1466 (2003), Ferris, M., et al.: J. Clin. Microbiol., 42, 5892 (2004),Formula:C10H11N3O5SColor and Shape:NeatMolecular weight:285.28Nifuratel
CAS:5-((Methylthio)methyl)-3-(((5-nitrofuran-2-yl)methylene)amino)oxazolidin-2-oneFormula:C10H11N3O5SPurity:98%Molecular weight:285.28












