CAS 496-67-3

Bromisoval

Description:

Bromisoval, with the CAS number 496-67-3, is a chemical compound that belongs to the class of barbiturates, specifically a derivative of isovalerylurea. It is primarily recognized for its sedative and hypnotic properties, making it useful in the medical field for inducing sleep and managing anxiety. The compound is characterized by its bromine substituent, which contributes to its pharmacological effects. Bromisoval is typically administered in oral form and is known for its relatively rapid onset of action. Its mechanism involves the enhancement of GABA (gamma-aminobutyric acid) activity in the central nervous system, leading to increased inhibitory neurotransmission. However, like other barbiturates, it carries a risk of dependence and overdose, necessitating careful monitoring during use. In terms of physical properties, Bromisoval is generally a white to off-white crystalline powder, soluble in organic solvents but less so in water. Its stability and reactivity are influenced by environmental conditions, making proper storage essential for maintaining its efficacy.

Formula: C₆H₁₁BrN₂O₂

InChI: InChI=1/C6H11BrN2O2/c1-3(2)4(7)5(10)9-6(8)11/h3-4H,1-2H3,(H3,8,9,10,11)/t4-/m0/s1

InChI key: InChIKey=CMCCHHWTTBEZNM-UHFFFAOYSA-N

SMILES: C(C(C(C)C)Br)(NC(N)=O)=O

Synonyms:

• (2-Bromo-3-methylbutanoyl)urea
• (2R)-2-bromo-N-carbamoyl-3-methylbutanamide
• (2S)-2-bromo-N-carbamoyl-3-methylbutanamide
• (RS)-2-Bromoisovalerylurea
• (α-Bromoisovaleryl)urea
• 2-Bromo-3-methylbutyrylurea
• 2-Bromoisovalerylurea
• 2-bromo-N-carbamoyl-3-methylbutanamide
• Abroval
• Alluval
• Alural
• Bromaral
• Bromcarbamide
• Bromisovalerylurea
• Bromisovalum
• Bromizoval
• Bromocarbamide
• Bromoisovalum
• Bromoval
• Bromovalerocarbamide
• Bromovaleroylurea
• Bromovalerylurea
• Bromoxil
• Bromural
• Bromuvan
• Bromvalerylurea
• Bromvaletone
• Bromvalurea
• Bromyl
• Brovalin
• Brovalurea
• Brovarin
• Butanamide, N-(aminocarbonyl)-2-bromo-3-methyl-
• Calmotin
• Dagrabromyl
• Dibroluur
• Dormigene
• Isobromyl
• N-(Aminocarbonyl)-2-bromo-3-methylbutanamide
• Pivadorm
• Pivadorn
• Somnurol
• Upiol
• Urea, (2-bromo-3-methylbutyryl)-
• Uvaleral
• α-Bromisovalerylurea
• α-Bromo-β-dimethylpropanoylurea
• α-Bromoisovaleric acid ureide
• α-Bromoisovaleroylurea
• Bromisoval
• 1-(2-BROMOISOVALERYL)UREA
• BROMOISOVALERYLUREA
• BROMO-ISO-VALERYLUREA (ALPHA)
• ALPHA(BROMOISOVALERYL)UREA
• 2-Monobromoisovalerylurea
• (alpha-Bromoisovaleroyl)urea
• RARECHEM AX KI 5046
• alpha-Bromisovalerylurea
• LABOTEST-BB LT00134620
• 2-Bromo-isovaleryl urea
• 2-Bromisovalerylmocovina
• (2-bromo-3-methylbutyryl)-ure
• 2-Bromo-3-methylbutyrylurea deaux Base GP

Bromisoval, 10mM (in DMSO)

CAS: 496-67-3

Bromisoval, 10mM (in DMSO)

Formula: C₆H₁₁BrN₂O₂

Purity: ≥98%, 10 mM in DMSO

Molecular weight: 223.07

Ref: 54-BUP19936

Bromisoval

CAS: 496-67-3

Bromisoval (Isobromyl) is a mild hypnotic and sedative with potential toxicity.

Formula: C₆H₁₁BrN₂O₂

Purity: 98.86%

Color and Shape: Solid

Molecular weight: 223.07

Ref: TM-T0227

BROMISOVAL

CAS: 496-67-3

Formula: C₆H₁₁BrN₂O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 223.0677

Ref: IN-DA003OJZ

1-(2-Bromoisovaleryl)Urea

CAS: 496-67-3

1-(2-Bromoisovaleryl)Urea

Formula: C₆H₁₁BrN₂O₂

Purity: >98.0%

Molecular weight: 223.07

Ref: 54-OR1029210

Bromisoval

CAS: 496-67-3

Bromisoval

Purity: ≥98%

Molecular weight: 223.07g/mol

Ref: 54-BUP17637

Bromisoval

CAS: 496-67-3

Formula: C₆H₁₁BrN₂O₂

Molecular weight: 223.07

Ref: 4Z-B-193001

Bromisoval

CAS: 496-67-3

Formula: C₆H₁₁BrN₂O₂

Molecular weight: 223.07

Ref: 7W-GP4734

2-Bromo-3-methylbutyrylurea

Controlled Product

CAS: 496-67-3

Applications 2-Bromo-3-methylbutyrylurea is a hypnotic and sedative drug marketed over the counter in Asian under various brand names.
References Koenig, H., et al.: Clinc. Toxicol. Anal., 1, 367 (2009); Marrero-Ponce, Y., et al.: Euro. J. Med. Chem., 46, 5736 (2011);

Formula: C₆H₁₁BrN₂O₂

Color and Shape: Neat

Molecular weight: 223.07

Ref: TR-B685130

Bromisoval

CAS: 496-67-3

2-Bromo-N-carbamoyl-3-methylbutanamide

Formula: C₆H₁₁BrN₂O₂

Purity: 97%

Molecular weight: 223.07

Ref: IN-DG118745

2-Bromo-N-carbamoyl-3-methylbutanamide

CAS: 496-67-3

Formula: C₆H₁₁BrN₂O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 223.07

Ref: 10-F517799

Bromisoval

Controlled Product

CAS: 496-67-3

Bromisoval is a drug that is used to treat symptoms of oxidative injury. It is a cytostatic drug, which inhibits the growth of epidermal cells in culture. Bromisoval has been shown to be toxic and inhibit protein synthesis in human serum and in pathogenic mechanisms. However, it does not cause toxicity or inhibit protein synthesis in bowel disease. Bromisoval has also been shown to have anti-inflammatory properties, which may be due to its inhibition of prostaglandin synthesis.

Formula: C₆H₁₁BrN₂O₂

Purity: Min. 95%

Molecular weight: 223.07 g/mol

Ref: 3D-FB38229

Bromisoval

CAS: 496-67-3

Formula: C₆H₁₁BrN₂O₂

Molecular weight: 223.07

Ref: ST-EA-CP-B194000

1-(2-Bromoisovaleryl)urea

CAS: 496-67-3

Formula: C₆H₁₁BrN₂O₂

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 223.07

Ref: 3B-B2842