CAS 497-23-4

2(5H)-Furanone

Description:

2(5H)-Furanone, also known as 2-pyrone, is a cyclic compound characterized by a six-membered lactone ring containing both oxygen and carbon atoms. It features a double bond between the carbon atoms adjacent to the oxygen, contributing to its reactivity and stability. This compound is typically colorless to pale yellow and has a sweet, fruity odor, often associated with various natural flavors and fragrances. It is soluble in organic solvents and exhibits moderate solubility in water. 2(5H)-Furanone is known for its role in the food industry, where it is used as a flavoring agent, and it also has applications in the synthesis of pharmaceuticals and agrochemicals. The compound can undergo various chemical reactions, including hydrolysis and oxidation, making it a versatile intermediate in organic synthesis. Additionally, it has been studied for its potential biological activities, including antimicrobial and antioxidant properties. Overall, 2(5H)-Furanone is an important compound in both industrial and research contexts due to its unique chemical structure and functional properties.

Formula: C₄H₄O₂

InChI: InChI=1S/C4H4O2/c5-4-2-1-3-6-4/h1-2H,3H2

InChI key: InChIKey=VIHAEDVKXSOUAT-UHFFFAOYSA-N

SMILES: O=C1C=CCO1

Synonyms:

• 2(5H)-Furanone
• 2,5-Dihydrofuranone
• 2-Buten-1,4-olide
• 2-Buten-4-olide
• 2-Butenoic acid, 4-hydroxy-, γ-lactone
• 2-Oxo-2,5-dihydrofuran
• 2H-Furan-5-one
• 4-Hydroxy-2-butenoic acid lactone
• 4-Hydroxy-2-butenoic acid γ-lactone
• 5-Oxo-2,5-dihydrofuran-3-yl ester
• 5H-Furan-2-one
• Cratone
• Crotonic acid, 4-hydroxy-, γ-lactone
• Furan-2(5H)-on
• Isocrotonolactone
• Nsc 197009
• Nsc 51296
• furan-2(5H)-ona
• furan-2(5H)-one
• furanne-2(5H)-one
• g-Crotonolactone
• Δ^α,β-Butenolide
• Δα,β-Butenolide
• α,β-Crotonolactone
• γ-Crotolactone

gamma-Crotonolactone

CAS: 497-23-4

Formula: C₄H₄O₂

Purity: >93.0%(GC)

Color and Shape: Colorless to Light orange to Yellow clear liquid

Molecular weight: 84.07

Ref: 3B-C1078

2(5H)-Furanone, 96%

CAS: 497-23-4

2(5H)-Furanone is employed in the preparation of 5-substituted 2(5H) furanones (gamma-butenolides) catalyzed by bifunctional aminothiourea and aminosquaramide organocatalysts through direct aldol reaction with aromatic aldehydes. Further, it is used in the synthesis of lignans by Michael addition re

Formula: C₄H₄O₂

Purity: 96%

Color and Shape: Clear colorless to yellow, Liquid

Molecular weight: 84.07

Ref: 02-L13142

Furan-2(5H)-one

CAS: 497-23-4

Furan-2(5H)-one

Formula: C₄H₄O₂

Purity: 97%

Color and Shape: Pale brown Liquid

Molecular weight: 84.07336

Ref: 54-OR2878

Butenolide

CAS: 497-23-4

Butenolide

Purity: 97%

Ref: 54-BIBR1016

2(5H)-Furanone

CAS: 497-23-4

2(5H)-Furanone

Formula: C₄H₄O₂

Purity: >97%

Color and Shape: Liquid

Molecular weight: 84.07

Ref: 54-BI12168

2(5H)-Furanone

CAS: 497-23-4

2(5H)-Furanone, with CAS No. 497-23-4, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. 2(5H)-Furanone provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Formula: C₄H₄O₂

Purity: 97.87%

Molecular weight: 84.0734

Ref: TM-PDK0240

2(5H)-Furanone

CAS: 497-23-4

Formula: C₄H₄O₂

Purity: 98%

Color and Shape: Liquid

Molecular weight: 84.0734

Ref: IN-DA0037F3

2-Furanone

CAS: 497-23-4

Stability Moisture Sensitive
Applications 2-Furanone is a heterocyclic organic compound that is used widely in the synthetic preparation of pharmaceutical goods.
References Kim, H.K., et al.: Plant. Pathol. J., 28, 259 (2012); Nam, S., et al.: J. Agr. Food. Chem., 60, 9097 (2012); Durchschein, K., et al.: Eur. J. Org. Chem., 2012, 4963 (2012);

Formula: C₄H₄O₂

Color and Shape: Neat

Molecular weight: 84.07

Ref: TR-F864050

2(5H)-Furanone

CAS: 497-23-4

2(5H)-Furanone is a naturally occurring compound that has been found to have hypoglycemic effects. Studies have shown that 2(5H)-furanone inhibits the activity of cox-2, an enzyme involved in the synthesis of prostaglandins, which are inflammatory compounds. This chemical may be useful as an anti-inflammatory agent and for the treatment of bowel diseases. 2(5H)-Furanone also has antimicrobial properties and has been shown to inhibit the growth of animal cells that are resistant to anticancer drugs. It binds to cell nuclei and disrupts DNA synthesis by competing with basic proteins for binding sites on DNA strands. The chemical structure of 2(5H)-furanone is very similar to butenolide, a natural plant compound used in traditional Chinese medicine; both compounds have been shown to inhibit COX-2 activity.

Formula: C₄H₄O₂

Purity: Min. 95%

Color and Shape: Clear Liquid

Molecular weight: 84.07 g/mol

Ref: 3D-FF45970

2(5H)-Furanone

CAS: 497-23-4

Formula: C₄H₄O₂

Color and Shape: Liquid

Molecular weight: 84.07

Ref: BE-BePure-26986

2(5H)-Furanone

CAS: 497-23-4

Formula: C₄H₄O₂

Purity: 96%

Color and Shape: Liquid

Molecular weight: 84.074

Ref: 10-F095003

Furan-2(5H)-one

CAS: 497-23-4

Furan-2(5H)-one

Formula: C₄H₄O₂

Purity: 97%

Molecular weight: 84.07

Ref: IN-DG62697