CAS 498-95-3

Nipecotic acid

Description:

Nipecotic acid, with the CAS number 498-95-3, is a bicyclic organic compound that is structurally related to the amino acid proline. It features a piperidine ring, which contributes to its unique properties. Nipecotic acid is known for its role as a GABA (gamma-aminobutyric acid) uptake inhibitor, making it of interest in neuropharmacology for its potential effects on neurotransmission and its implications in treating neurological disorders. The compound is typically a white crystalline solid and is soluble in water and various organic solvents, which facilitates its use in biochemical applications. Its molecular structure includes a carboxylic acid functional group, which contributes to its acidity and reactivity. Nipecotic acid has been studied for its potential therapeutic effects, particularly in relation to anxiety and epilepsy, due to its influence on GABAergic signaling. However, further research is necessary to fully understand its pharmacological profile and therapeutic potential.

Formula: C₆H₁₁NO₂

InChI: InChI=1/C6H11NO2/c8-6(9)5-2-1-3-7-4-5/h5,7H,1-4H2,(H,8,9)

InChI key: InChIKey=XJLSEXAGTJCILF-UHFFFAOYSA-N

SMILES: C(O)(=O)C1CCCNC1

Synonyms:

• (±)-β-Homoproline
• 3-Carboxypiperidine
• 3-Piperidinecarboxylic acid
• <span class="text-smallcaps">D</smallcap><smallcap>L</span>-Nipecotic acid
• DL-Nipecotic acid
• H-DL-Nip-OH~(+/-)-Piperidine-3-carboxylic acid
• Hexahydronicotinic acid
• Piperidin-3-carboxylic acid
• Piperidine-3-Carboxylic Acid
• Nipecotic acid
• (±)-Nipecotic acid
• D-NIPECOTIC ACID
• H-DL-NIPC-OH
• D(-)-NIPECOTIC ACID
• H-NIP-OH
• D-Piperidine-3-carboxylic acid
• (+/-)-3-PIPERIDINE CARBOXYLIC ACID
• (-)-D-NIPECOTIC ACID
• (3R)-(-)-PIPERIDIN-3-YLCARBOXYLIC ACID
• LABOTEST-BB LT00233199
• D-3-PIPERIDINECARBOXYLIC ACID
• DL-3-PIPERIDINECARBOXYLIC ACID
• H-D-NIPC-OH
• L-NIPECOTIC ACID

3-Piperidinecarboxylic Acid

CAS: 498-95-3

Formula: C₆H₁₁NO₂

Purity: >98.0%(T)

Color and Shape: White to Orange to Green powder to crystal

Molecular weight: 129.16

Ref: 3B-N0420

Nipecotic acid, 98%

CAS: 498-95-3

GABA reuptake inhibitor This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand

Formula: C₆H₁₁NO₂

Purity: 98%

Color and Shape: Crystals or powder or crystalline powder, White to cream or pale yellow

Molecular weight: 129.16

Ref: 02-B24723

H-DL-Nip-OH

CAS: 498-95-3

Formula: C₆H₁₁NO₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 129.1570

Ref: IN-DA003T49

Nipecotic acid

CAS: 498-95-3

Compound PDK0243, with CAS No. 498-95-3, is a fragment molecule that serves as an important scaffold for molecular linking, expansion, and modification. Compound PDK0243 provides a structural basis and research tool for the design and screening of novel drug candidates, and is commonly used in drug discovery, drug synthesis, and related research.

Formula: C₆H₁₁NO₂

Color and Shape: Off-White To Pale Yellow-Beige Powder

Molecular weight: 129.16

Ref: TM-PDK0243

Nipecotic acid

CAS: 498-95-3

Formula: C₆H₁₁NO₂

Purity: (Titration) ≥ 97.5%

Color and Shape: White to pale yellow or light-brown powder or crystals

Molecular weight: 129.16

Ref: 7W-GK5500

Piperidine-3-carboxylic acid

CAS: 498-95-3

Piperidine-3-carboxylic acid

Formula: C₆H₁₁NO₂

Purity: 98%

Color and Shape: off white solid

Molecular weight: 129.16g/mol

Ref: 54-OR8589

Nipecotic acid

CAS: 498-95-3

Nipecotic acid is a competitive inhibitor of glutamate. It binds to the extracellular site of the glutamate-gated chloride channel and blocks the influx of chloride ions into the cell, resulting in an increase in intracellular chloride ion concentrations. Nipecotic acid has been shown to have a variety of effects on behaviour, including increased rotarod performance and improved motor learning in rats. This drug also inhibits uptake of hydrogen tartrate into cells, which is essential for catabolism of glucose by glycolysis. The effect on locomotor activity was not observed when nipecotic acid was administered orally or intraperitoneally. Nipecotic acid has a high resistance to hydrolysis by p-hydroxybenzoic acid and is used as an analytical standard for this compound.

Formula: C₆H₁₁NO₂

Color and Shape: Powder

Molecular weight: 129.15 g/mol

Ref: 3D-FN02349

(+/-)-Piperidine-3-carboxylic acid(DL-Nipecotic acid)

CAS: 498-95-3

Formula: C₆H₁₁NO₂

Purity: 98%

Color and Shape: Solid, Crystalline Powder

Molecular weight: 129.159

Ref: 10-F013177

(+/-)-Nipecotic Acid

Controlled Product

CAS: 498-95-3

Applications (+/-)-Nipecotic Acid (cas# 498-95-3) is a compound useful in organic synthesis.

Formula: C₆H₁₁NO₂

Color and Shape: Neat

Molecular weight: 129.16

Ref: TR-N478400

Fexofenadine Impurity 14

CAS: 498-95-3

Formula: C₆H₁₁NO₂

Molecular weight: 129.16

Ref: ST-EA-CP-F13023