CAS 50-11-3

Metharbital

Description:

Metharbital is a barbiturate derivative that functions primarily as a central nervous system depressant. It is characterized by its sedative and hypnotic properties, making it useful in the treatment of insomnia and anxiety disorders. The chemical structure of metharbital includes a barbituric acid core, which is modified to enhance its pharmacological effects. It typically appears as a white crystalline powder and is soluble in water and alcohol. Metharbital acts by modulating the activity of gamma-aminobutyric acid (GABA) receptors, leading to increased inhibitory neurotransmission. While it can be effective for short-term use, the potential for dependence and tolerance necessitates careful monitoring and regulation. Due to the risk of overdose and the availability of safer alternatives, the clinical use of metharbital has declined significantly. It is classified as a controlled substance in many jurisdictions, reflecting concerns over its abuse potential and side effects, which can include drowsiness, dizziness, and impaired coordination.

Formula: C₉H₁₄N₂O₃

InChI: InChI=1S/C9H14N2O3/c1-4-9(5-2)6(12)10-8(14)11(3)7(9)13/h4-5H2,1-3H3,(H,10,12,14)

InChI key: InChIKey=FWJKNZONDWOGMI-UHFFFAOYSA-N

SMILES: C(C)C1(CC)C(=O)N(C)C(=O)NC1=O

Synonyms:

• 1-Methyl-5,5-diethylbarbiturate
• 1-Methylbarbital
• 5,5-Diethyl-1-methyl-2,4,6(1H,3H,5H)-pyrimidinetrione
• 5,5-Diethyl-1-methylbarbituric acid
• Barbituric acid, 5,5-diethyl-1-methyl-
• Endiemal
• Endiemalum
• Gemonil
• Gemonit
• Metabarbital
• Metarbital
• Methabarbital
• Methabarbitone
• Metharbital
• Metharbitone
• Methylbarbital
• N-Methylbarbital
• Nsc 27156
• Sch 412
• 5,5-diethyl-1-methylpyrimidine-2,4,6(1H,3H,5H)-trione
• 2,4,6(1H,3H,5H)-Pyrimidinetrione, 5,5-diethyl-1-methyl-

Metharbital

Controlled Product

CAS: 50-11-3

Formula: C₉H₁₄N₂O₃

Color and Shape: White

Molecular weight: 198.22

Ref: 61-FOR1656.00

Metharbital 1.0 mg/ml in Methanol

Controlled Product

CAS: 50-11-3

Formula: C₉H₁₄N₂O₃

Color and Shape: Colourless

Molecular weight: 198.22

Ref: 61-AMP1656.00-01

Metharbital

Controlled Product

CAS: 50-11-3

Formula: C₉H₁₄N₂O₃

Color and Shape: Neat

Molecular weight: 198.22

Ref: 86-MM1656.00

Methylbarbital

Controlled Product

CAS: 50-11-3

Applications Methylbarbital is a barbituate which displays anticonvulsant/antiepileptic activity.
References Lien, E. et al.: J. Pharm. Sci.., 68, 463 (1979); Kesselheim, A. et al.: Drugs, 70, 605 (2010);

Formula: C₉H₁₄N₂O₃

Color and Shape: Neat

Molecular weight: 198.22

Ref: TR-M288705

Methylbarbital (1.0mg/ml in Acetonitrile)

Controlled Product

CAS: 50-11-3

Formula: C₉H₁₄N₂O₃

Color and Shape: Single Solution

Molecular weight: 198.22

Ref: TR-KIT5850

Methylbarbital

Controlled Product

CAS: 50-11-3

Please enquire for more information about Methylbarbital including the price, delivery time and more detailed product information at the technical inquiry form on this page

Formula: C₉H₁₄N₂O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 198.22 g/mol

Ref: 3D-AAA05011