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CAS 50-28-2

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Estradiol

Description:
Estradiol, with the CAS number 50-28-2, is a potent estrogen steroid hormone primarily produced in the ovaries, although it is also synthesized in smaller amounts in the adrenal glands and testes. It plays a crucial role in the regulation of the menstrual cycle and reproductive system in females, as well as influencing various physiological processes in both sexes, including bone density, fat distribution, and cardiovascular health. Chemically, estradiol is characterized by its structure as a phenolic compound with a steroid backbone, featuring a hydroxyl group at the C-3 position and an aromatic A-ring. It is lipophilic, allowing it to easily cross cell membranes and bind to estrogen receptors, initiating a range of biological responses. Estradiol is also involved in various therapeutic applications, including hormone replacement therapy and treatment of certain hormone-sensitive cancers. Its synthesis and metabolism are tightly regulated, and imbalances can lead to various health issues, including reproductive disorders and osteoporosis.
Formula:C18H24O2
InChI:InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1
InChI key:InChIKey=VOXZDWNPVJITMN-ZBRFXRBCSA-N
SMILES:C[C@@]12[C@]([C@]3([C@@](C=4C(CC3)=CC(O)=CC4)(CC1)[H])[H])(CC[C@@H]2O)[H]
Synonyms:
  • (+)-3,17β-Estradiol
  • (17β)-Estra-1,3,5(10)-triene-3,17-diol
  • (8Alpha,9Beta,13Alpha,14Beta,17Alpha)-Estra-1,3,5(10)-Triene-3,17-Diol
  • (8R,9S,13S,14S,17S)-13-Methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
  • 1,3,5-Estratriene-3,17Beta-Diol
  • 13β-Methyl-1,3,5(10)-gonatriene-3,17β-ol
  • 17Beta-Estradiol
  • 17β-Estradiol
  • 17β-Oestradiol
  • 3,17-Epidihydroxyestratriene
  • See more synonyms
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