CAS 50-28-2
:Estradiol
Description:
Estradiol, with the CAS number 50-28-2, is a potent estrogen steroid hormone primarily produced in the ovaries, although it is also synthesized in smaller amounts in the adrenal glands and testes. It plays a crucial role in the regulation of the menstrual cycle and reproductive system in females, as well as influencing various physiological processes in both sexes, including bone density, fat distribution, and cardiovascular health. Chemically, estradiol is characterized by its structure as a phenolic compound with a steroid backbone, featuring a hydroxyl group at the C-3 position and an aromatic A-ring. It is lipophilic, allowing it to easily cross cell membranes and bind to estrogen receptors, initiating a range of biological responses. Estradiol is also involved in various therapeutic applications, including hormone replacement therapy and treatment of certain hormone-sensitive cancers. Its synthesis and metabolism are tightly regulated, and imbalances can lead to various health issues, including reproductive disorders and osteoporosis.
Formula:C18H24O2
InChI:InChI=1S/C18H24O2/c1-18-9-8-14-13-5-3-12(19)10-11(13)2-4-15(14)16(18)6-7-17(18)20/h3,5,10,14-17,19-20H,2,4,6-9H2,1H3/t14-,15-,16+,17+,18+/m1/s1
InChI key:InChIKey=VOXZDWNPVJITMN-ZBRFXRBCSA-N
SMILES:C[C@@]12[C@]([C@]3([C@@](C=4C(CC3)=CC(O)=CC4)(CC1)[H])[H])(CC[C@@H]2O)[H]
Synonyms:- (+)-3,17β-Estradiol
- (17β)-Estra-1,3,5(10)-triene-3,17-diol
- (8Alpha,9Beta,13Alpha,14Beta,17Alpha)-Estra-1,3,5(10)-Triene-3,17-Diol
- (8R,9S,13S,14S,17S)-13-Methyl-7,8,9,11,12,13,14,15,16,17-decahydro-6H-cyclopenta[a]phenanthrene-3,17-diol
- 1,3,5-Estratriene-3,17Beta-Diol
- 13β-Methyl-1,3,5(10)-gonatriene-3,17β-ol
- 17Beta-Estradiol
- 17β-Estradiol
- 17β-Oestradiol
- 3,17-Epidihydroxyestratriene
- 3,17Beta-Dihydroxy-1,3,5(10)-Estratriene
- 3,17β-Dihydroxyestra-1,3,5(10)-triene
- Aerodiol
- Alora
- Altrad
- Aquadiol
- Bardiol
- Benzogynestry
- Beta-Estradiol
- Climaderm
- Climara
- Compudose
- Corpagen
- Dermestril
- Destradiol
- Dihydrofolliculin
- Dihydromenformon
- Dihydrotheelin
- Dihydroxyestrin
- Dimenformon
- Diogyn
- Diogynets
- Divigel
- Elestrim
- Encore
- Estasorb
- Estra-1,3,5(10)-triene-3,17-diol
- Estra-1,3,5(10)-triene-3,17β-diol
- Estrace
- Estraderm
- Estradiol
- Estradiol-17β
- Estradot
- Estraldine
- Estrapatch
- Estredox
- Estreva
- Estring
- Estroclim
- Estrogel
- Estropause
- Estrovite
- Evamist
- Evorel
- FemSeven
- Femanest
- Femestral
- Femogen
- Fempatch
- Follicyclin
- Gelestra
- Ginosedol
- Gynergon
- Gynodiol
- Gynoestryl
- Imvexxy
- Innofem
- Lamdiol
- Macrodiol
- Menorest
- Menostar
- Nordicol
- Oesclim
- Oestergon
- Oestra-1,3,5(10)-triene-3,17β-diol
- Oestradiol
- Oestrogel
- Oestroglandol
- Ovahormon
- Ovasterol
- Ovastevol
- Ovocyclin
- Ovocylin
- Perlatanol
- Primofol
- Profoliol
- Progynon
- Sprediol
- Syndiol
- Systen
- Vagifem
- Vivelle
- Vivelle-Dot
- Zesteem
- Zumenon
- See more synonyms
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Found 20 products.
β-Estradiol, 99% (dry wt.), ca 3% water
CAS:-Estradiol is the major estrogen secreted by the premenopausal ovary. It acts as an estrogenic hormone receptor (ER) agonist and activator of PI 3-kinase. Further, it is used in the treatment of infertility in women, prostate cancer and breast cancer. It is also employed as an agent of stimulating fFormula:C18H24O2Purity:99%Color and Shape:Powder, WhiteMolecular weight:272.39(1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2(7),3,5-triene-5,14-diol
CAS:Formula:C18H24O2Purity:98%Color and Shape:SolidMolecular weight:272.3820Ref: IN-DA0034TI
500gTo inquire1g24.00€5g40.00€10g60.00€25g116.00€50g165.00€100g217.00€250g693.00€1kg1,138.00€5kg5,542.00€10kg10,886.00€Estradiol
CAS:Estradiol (E2) is a naturally occurring steroidal sex hormone that is essential for female fertility and maintenance of secondary sexual characteristics.Formula:C18H24O2Purity:98.25% - >99.99%Color and Shape:White Crystalline Powder Prisms From 80% Alcohol SolidMolecular weight:272.38Estradiol-13C2-d2 (Estradiol Valerate EP Impurity A-13C2-d2, Estriol EP Impurity D-13C2-d2, Ethinylestradiol EP Impurity D-13C2-d2)
CAS:Formula:C1613C2H22D2O2Molecular weight:276.38Estradiol
CAS:Formula:C18H24O2Purity:≥ 97.0% (dried basis)Color and Shape:White to almost white powderMolecular weight:272.39Estradiol (Estradiol Valerate EP Impurity A, Estradiol Benzoate EP Impurity A, Estriol EP Impurity D, Ethinylestradiol EP Impurity D)
CAS:Formula:C18H24O2Color and Shape:White To Off-White SolidMolecular weight:272.39β-Estradiol
CAS:Formula:C18H24O2Purity:>97.0%(GC)Color and Shape:White to Almost white powder to crystalMolecular weight:272.39GB 31660.2-2019 Antibiotics Mixture 168 30-100 µg/mL in Methanol
CAS:Controlled ProductColor and Shape:Mixture17-β-Estradiol 100 µg/mL in Acetonitrile
CAS:Controlled ProductFormula:C18H24O2Color and Shape:Single SolutionMolecular weight:272.3817β-Estradiol
CAS:Controlled ProductImpurity Ethinylestradiol EP Impurity D
Applications 17b-Estradiol is the major estrogen (1) secreted by the premenopausal ovary (2).This compound is a contaminant of emerging concern (CECs). Drinking water contaminant candidate list 3 (CCL 3) compound as per United States Environmental Protection Agency (EPA), environmental, and food contaminants.
References 1. Salole, E. et al.: Anal. Profiles Drug Subs. 1986 15, 23 283-3182. Lievertz, R. et al.: Am. J. Obstet. Gynecol. 1987 May;156(5):1289-93.Formula:C18H24O2Color and Shape:NeatMolecular weight:272.38b-Estradiol
CAS:Controlled ProductEstradiol is a synthetic or naturally occurring form of estrogen, predominantly sourced from ovarian secretions in females. It performs its mode of action by binding to estrogen receptors, ERα and ERβ, subsequently regulating gene expression and modulating various biological processes including reproductive system development, bone density maintenance, and cardiovascular function.Formula:C18H24O2Purity:Min. 97 Area-%Color and Shape:PowderMolecular weight:272.38 g/mol(1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2(7),3,5-triene-5,14-diol
CAS:Formula:C18H24O2Purity:97%Color and Shape:Solid, White powderMolecular weight:272.388Estradiol-(13,14,15,16,17,18-13C6)
CAS:Controlled ProductFormula:C12C6H24O2Color and Shape:NeatMolecular weight:278.34
![(1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2(7),3,5-triene-5,14-di…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA0034TI.jpg&w=3840&q=75)
![(1S,10R,11S,14S,15S)-15-methyltetracyclo[8.7.0.0^{2,7}.0^{11,15}]heptadeca-2(7),3,5-triene-5,14-di…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb%2FF358087.jpg&w=3840&q=75)
