CAS 50-48-6

Amitriptyline

Description:

Amitriptyline is a tricyclic antidepressant primarily used to treat major depressive disorder and certain types of chronic pain. Its chemical formula is C20H23N, and it features a tricyclic structure that includes three interconnected rings. Amitriptyline functions by inhibiting the reuptake of neurotransmitters such as serotonin and norepinephrine, thereby increasing their availability in the synaptic cleft, which contributes to its antidepressant effects. The substance is typically administered in oral form and is known for its sedative properties, making it useful for patients with insomnia related to depression. Common side effects may include dry mouth, drowsiness, and weight gain, among others. Amitriptyline is also utilized off-label for conditions like anxiety disorders, migraine prophylaxis, and neuropathic pain. Due to its pharmacological profile, it is essential to monitor patients for potential cardiovascular effects and interactions with other medications. As with all antidepressants, it is crucial to follow a healthcare provider's guidance regarding dosage and duration of treatment.

Formula: C₂₀H₂₃N

InChI: InChI=1S/C20H23N/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20/h3-6,8-12H,7,13-15H2,1-2H3

InChI key: InChIKey=KRMDCWKBEZIMAB-UHFFFAOYSA-N

SMILES: C(CCN(C)C)=C1C=2C(CCC=3C1=CC=CC3)=CC=CC2

Synonyms:

• 1-Propanamine, 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-
• 3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine
• 3-(10,11-Dihydrodibenzo(A,D)Cyclohepten-5-Ylidene)Propyldimethylamine
• 5-(3'-Dimethylaminopropylidene)-dibenzo-[a,d][1,4]-cycloheptadiene
• 5-(3-Dimethylaminopropylidene)-5H-dibenzo[a,d]-10,11-dihydrocycloheptene
• 5-(γ-Dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo[a,d]cycloheptene
• 5-(γ-Dimethylaminopropylidene)-5H-dibenzo(a,d)(1,4)cycloheptadiene
• 5H-Dibenzo[a,d]cycloheptene-Δ5,γ-propylamine, 10,11-dihydro-N,N-dimethyl-
• 5H-Dibenzo[a,d]cycloheptene-Δ^5,γ-propylamine, 10,11-dihydro-N,N-dimethyl-
• Adepress
• Amitriprolidine
• Amitriptilina
• Amitriptylin
• Damilen
• Damitriptyline
• Flavyl
• Mk 230
• N 750
• Proheptadiene
• Seroten
• Triptanol
• Triptisol

Amitriptyline Hydrochloride

CAS: 50-48-6, 549-18-8

Formula: C₂₀H₂₃N·HCl

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 313.87

Ref: 3B-A0908

Amitriptyline

CAS: 50-48-6

Amitriptyline

Purity: ≥98%

Molecular weight: 277.4g/mol

Ref: 54-BUP11126

Amitryptylline hydrochloride

CAS: 50-48-6

Ref: 7W-GP2252

Amitriptyline

CAS: 50-48-6

Amitriptyline: a tricyclic antidepressant used for depression and neuropathic pain.

Formula: C₂₀H₂₃N

Purity: 98.24% - 99.64%

Color and Shape: Crystals Solid

Molecular weight: 277.4

Ref: TM-T22240

Amitriptyline

Controlled Product

CAS: 50-48-6

Stability Light Sensitive

Formula: C₂₀H₂₃N

Color and Shape: Neat

Molecular weight: 277.4033

Ref: TR-A640860

Nortriptyline EP Impurity F

CAS: 50-48-6

Formula: C₂₀H₂₃N

Molecular weight: 277.41

Ref: ST-EA-CP-N15006