CAS 50-48-6: Amitriptyline

Description: Amitriptyline is a tricyclic antidepressant primarily used to treat major depressive disorder and certain types of chronic pain. Its chemical formula is C20H23N, and it features a tricyclic structure that includes three interconnected rings. Amitriptyline functions by inhibiting the reuptake of neurotransmitters such as serotonin and norepinephrine, thereby increasing their availability in the synaptic cleft, which contributes to its antidepressant effects. The substance is typically administered in oral form and is known for its sedative properties, making it useful for patients with insomnia related to depression. Common side effects may include dry mouth, drowsiness, and weight gain, among others. Amitriptyline is also utilized off-label for conditions like anxiety disorders, migraine prophylaxis, and neuropathic pain. Due to its pharmacological profile, it is essential to monitor patients for potential cardiovascular effects and interactions with other medications. As with all antidepressants, it is crucial to follow a healthcare provider's guidance regarding dosage and duration of treatment.

Formula: C₂₀H₂₃N

InChI: InChI=1S/C20H23N/c1-21(2)15-7-12-20-18-10-5-3-8-16(18)13-14-17-9-4-6-11-19(17)20/h3-6,8-12H,7,13-15H2,1-2H3

InChI key: InChIKey=KRMDCWKBEZIMAB-UHFFFAOYSA-N

SMILES: C=1C=CC2=C(C1)C(=CCCN(C)C)C=3C=CC=CC3CC2

Synonyms:

• 1-Propanamine, 3-(10,11-dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-
• 3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)-N,N-dimethyl-1-propanamine
• 3-(10,11-Dihydrodibenzo(A,D)Cyclohepten-5-Ylidene)Propyldimethylamine
• 5-(3'-Dimethylaminopropylidene)-dibenzo-[a,d][1,4]-cycloheptadiene
• 5-(3-Dimethylaminopropylidene)-5H-dibenzo[a,d]-10,11-dihydrocycloheptene
• 5-(γ-Dimethylaminopropylidene)-10,11-dihydro-5H-dibenzo[a,d]cycloheptene
• 5-(γ-Dimethylaminopropylidene)-5H-dibenzo(a,d)(1,4)cycloheptadiene
• 5H-Dibenzo[a,d]cycloheptene-Δ5,γ-propylamine, 10,11-dihydro-N,N-dimethyl-
• 5H-Dibenzo[a,d]cycloheptene-Δ^5,γ-propylamine, 10,11-dihydro-N,N-dimethyl-
• Adepress
• Amitriprolidine
• Amitriptilina
• Amitriptylin
• Damilen
• Damitriptyline
• Flavyl
• Mk 230
• N 750
• Proheptadiene
• Seroten
• Triptanol
• Triptisol
• Amitriptyline

Amitriptyline

CAS: 50-48-6

• Purity: ≥98%
• Molecular weight: 277.4g/mol

Amitryptylline hydrochloride

CAS: 50-48-6

Amitriptyline Hydrochloride

CAS: 50-48-6549-18-8

• Formula: C₂₀H₂₃N·HCl
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 313.87

Amitriptyline

CAS: 50-48-6

Amitriptyline: a tricyclic antidepressant used for depression and neuropathic pain.

• Formula: C₂₀H₂₃N
• Purity: 98.24% - 99.64%
• Color and Shape: Crystals Solid
• Molecular weight: 277.4

Amitriptyline

CAS: 50-48-6

Stability Light Sensitive

• Formula: C₂₀H₂₃N
• Color and Shape: Neat
• Molecular weight: 277.4033

Nortriptyline EP Impurity F

CAS: 50-48-6

• Formula: C₂₀H₂₃N
• Molecular weight: 277.41