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CAS 50-50-0

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Estradiol benzoate

Description:
Estradiol benzoate is a synthetic derivative of estradiol, a naturally occurring estrogen hormone. It is characterized by its benzoate ester form, which enhances its lipid solubility and alters its pharmacokinetic properties. This compound typically appears as a white to off-white crystalline powder and is often used in hormone replacement therapy and in veterinary medicine for reproductive management. Estradiol benzoate is known for its ability to bind to estrogen receptors, thereby exerting estrogenic effects in target tissues. Its solubility in organic solvents, such as ethanol and chloroform, allows for various formulation options, including injectable preparations. The compound is generally stable under normal conditions but should be stored away from light and moisture to maintain its efficacy. As with other estrogens, it may have side effects and contraindications, necessitating careful consideration in therapeutic applications. Overall, estradiol benzoate plays a significant role in both human and animal health, particularly in managing hormonal imbalances.
Formula:C25H28O3
InChI:InChI=1/C25H28O3/c1-25-14-13-20-19-10-8-18(28-24(27)16-5-3-2-4-6-16)15-17(19)7-9-21(20)22(25)11-12-23(25)26/h2-6,8,10,15,20-23,26H,7,9,11-14H2,1H3/t20-,21-,22+,23+,25+/m1/s1
InChI key:InChIKey=UYIFTLBWAOGQBI-BZDYCCQFSA-N
SMILES:C[C@@]12[C@]([C@]3([C@@](C=4C(CC3)=CC(OC(=O)C5=CC=CC=C5)=CC4)(CC1)[H])[H])(CC[C@@H]2O)[H]
Synonyms:
  • (17Beta)-17-Hydroxyestra-1,3,5(10)-Trien-3-Yl Benzoate
  • (17Beta)-3-Hydroxyestra-1,3,5(10)-Trien-17-Yl Benzoate
  • (17beta)-Estra-1,3,5(10)-triene-3,17-diol 3-benzoate
  • 1,3,5(10)-Estratriene-3,17-diol-3-benzoate
  • 1,3,5(10)-Estratriene-3,17b-diol 3-benzoate
  • 1,3,5(10)-Oestratriene-3,17-Beta-Diol3-Benzoate
  • 1,3,5(10)-Oestratriene-3,17-beta-diol 3-benzoate
  • 17-Beta-Estradiolmonobenzoate
  • 17-Beta-Oestradiol3-Benzoate
  • 17-Hydroxyestra-1(10),2,4-trien-3-yl benzoate
  • See more synonyms
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