CAS 50-86-2

4-Acetamidosalicylic acid

Description:

4-Acetamidosalicylic acid, also known as paracetamol or acetaminophen, is an organic compound with the molecular formula C8H9NO3. It is characterized by its white crystalline appearance and is soluble in water, alcohol, and ether. This compound features an acetamido group (-NHCOCH3) attached to the para position of a salicylic acid structure, which contributes to its analgesic and antipyretic properties. It is widely used in pharmaceuticals for pain relief and fever reduction. The compound exhibits a melting point that typically falls within a specific range, indicating its solid-state characteristics under standard conditions. Additionally, 4-acetamidosalicylic acid has a relatively low toxicity profile when used at recommended doses, making it a common choice for over-the-counter medications. Its mechanism of action involves the inhibition of cyclooxygenase enzymes, leading to a decrease in the synthesis of prostaglandins, which are mediators of pain and inflammation. Overall, this compound is a vital component in modern medicine, valued for its effectiveness and safety.

Formula: C₉H₉NO₄

InChI: InChI=1S/C9H9NO4/c1-5(11)10-6-2-3-7(9(13)14)8(12)4-6/h2-4,12H,1H3,(H,10,11)(H,13,14)

InChI key: InChIKey=YBTVSGCNBZPRBD-UHFFFAOYSA-N

SMILES: C(O)(=O)C1=C(O)C=C(NC(C)=O)C=C1

Synonyms:

• 2-Hydroxy-4-acetamidobenzoic acid
• 3-Hydroxy-4-carboxyacetanilide
• 4-(Acetylamino)-2-hydroxybenzoic acid
• 4-Acetamido-2-hydroxybenzoic acid
• 4-Acetamidosalicylic acid
• 4-Acetaminosalicylic acid
• 4-Azetaminosalizylsaeure
• 4-Azetaminosalizylsaeure [German]
• Acide 4-acetaminosalicylique
• Acide 4-acetaminosalicylique [French]
• Benzoic acid, 4-(acetylamino)-2-hydroxy-
• Benzoic acid, 4-(acetylamino)-2-hydroxy- (9CI)
• Benzoic acid, 4-acetamido-2-hydroxy-
• Brn 0395899
• N-Acetyl-4-aminosalicyclic acid
• N-Acetyl-4-aminosalicylic acid
• N-Acetyl-p-aminosalicylic acid
• N-Acetyl-pas
• Nsc 54182
• Salicylic acid, 4-acetamido-
• Ws 176
• p-(Acetylamino)salicylic acid
• p-Acetamidosalicylic acid

4-Acetamidosalicylic acid

CAS: 50-86-2

Formula: C₉H₉NO₄

Purity: 97%

Color and Shape: Solid

Molecular weight: 195.1721

Ref: IN-DA00DE9Y

4-Acetamido-2-hydroxybenzoic acid

CAS: 50-86-2

4-Acetamido-2-hydroxybenzoic acid

Purity: ≥95%

Molecular weight: 195.17g/mol

Ref: 54-OR59476

Metoclopramide EP Impurity H

CAS: 50-86-2

Formula: C₉H₉NO₄

Color and Shape: Off-White Solid

Molecular weight: 195.17

Ref: 4Z-M-601

4-(Acetylamino)-2-hydroxybenzoic Acid

Controlled Product

CAS: 50-86-2

Formula: C₉H₉NO₄

Color and Shape: Neat

Molecular weight: 195.17

Ref: 86-MM0073.08

5-Acetaminosalicylic Acid

Controlled Product

CAS: 50-86-2, 51-59-2

Color and Shape: Neat

Ref: 86-MM0217.02

N-Acetyl-4-aminosalicylic Acid

Controlled Product

CAS: 50-86-2

Impurity Metoclopramide EP Impurity H
Applications N-Acetyl-4-aminosalicylic Acid (Metoclopramide EP Impurity H) is hydroxybenzoic acid that is a versatile reactant used in the preparation of salicylanilide derivatives as inhibitors of the protein tyrosine kinase epidermal growth factor receptor.
References Liechti, C., et al.: Eur. J. Med. Chem., 39, 11 (2004);

Formula: C₉H₉NO₄

Color and Shape: Off White

Molecular weight: 195.17

Ref: TR-A168325

Metoclopramide EP Impurity H

CAS: 50-86-2

Formula: C₉H₉NO₄

Molecular weight: 195.17

Ref: ST-EA-CP-M15008

N-Acetyl-4-aminosalicylic acid

CAS: 50-86-2

N-Acetyl-4-aminosalicylic acid is an active site directed probe for the detection of salicylic acid. It has a fluorescence emission maximum at 370 nm and a fluorescence quantum yield of 0.93. N-Acetyl-4-aminosalicylic acid can be used to analyze samples, such as wastewater and human urine, which contain salicylic acid. The probe is protonated in the presence of salicylic acid and then binds to the acceptor in the sample with a bimodal distribution. The fluorescence resonance energy transfer (FRET) process between the donor and acceptor leads to an increase in fluorescence intensity that can be detected by electrophoresis methods. This probe also has a conformational change when it binds to its target, which allows for easy separation from other components in the sample by size exclusion chromatography.

Formula: C₉H₉NO₄

Purity: Min. 95%

Color and Shape: Slightly Brown Powder

Molecular weight: 195.17 g/mol

Ref: 3D-FA17083

4-Acetamido-2-hydroxybenzoic acid

CAS: 50-86-2

Purity: 97%

Molecular weight: 195.173996

Ref: 10-F600588

N-Acetyl-4-aminosalicylic Acid-d3

Controlled Product

CAS: 50-86-2

Formula: C₉D₃H₆NO₄

Color and Shape: Neat

Molecular weight: 198.19

Ref: TR-A168327