CAS 51-59-2

N-Acetyl-5-aminosalicylic acid

Description:

N-Acetyl-5-aminosalicylic acid, also known as 5-Acetamido-2-hydroxybenzoic acid, is a chemical compound characterized by its structural features that include an acetyl group and an amino group attached to a salicylic acid backbone. It is a white to off-white crystalline powder that is soluble in water and organic solvents, making it versatile for various applications. This compound exhibits anti-inflammatory and analgesic properties, which are attributed to its ability to inhibit certain biochemical pathways involved in pain and inflammation. It is often studied in the context of pharmaceutical formulations and may serve as an intermediate in the synthesis of other medicinal compounds. The presence of both hydroxyl and amino functional groups contributes to its reactivity and potential interactions with biological systems. As with many chemical substances, proper handling and safety precautions are essential due to its potential effects on health and the environment.

Formula: C₉H₉NO₄

InChI: InChI=1/C9H9NO4/c1-5(11)10-6-2-3-8(12)7(4-6)9(13)14/h2-4,12H,1H3,(H,10,11)(H,13,14)

InChI key: InChIKey=GEFDRROBUCULOD-UHFFFAOYSA-N

SMILES: N(C(C)=O)C1=CC(C(O)=O)=C(O)C=C1

Synonyms:

• 2-Hydroxy-5-(acetylamino)benzoic acid
• 2-Hydroxy-5-acetamidobenzoic acid
• 2-Hydroxy-5-acetylaminobenzoic acid
• 3-Carboxyparacetamol
• 5-(Acetylamino)-2-Hydroxybenzoic Acid
• 5-(Acetylamino)salicylic acid
• 5-Acetamido-2-hydroxybenzoic acid
• Acetylmesalazine
• Benzoic acid, 5-(acetylamino)-2-hydroxy-
• Benzoic acid, 5-(acetylamino)-2-hydroxy- (9CI)
• Cj 46A
• N-Acetyl-5-aminosalicylic acid
• Nsc 54183
• Salicylic acid, 5-acetamido-
• Salicylic acid, 5-acetamido- (8CI)
• 5-Acetamidosalicylic acid
• CJ 46A-d3
• N-ACETYL MESALAMINE
• 5-Acetylamino-2-hydroxybenzoic Acid5-Acetamidosalicylic AcidN-Acetylmesalamine
• 5-(acetylamino)-2-hydroxybenzoic acid(SALTDATA: FREE)
• Mesalazine N-Acetyl IMpurity
• 5-(Acetylamino-d3)-2-hydroxybenzoic Acid
• N-ACETYL MESALAMINE-D3
• 5-acetamido-2-hydroxy-benzoic acid
• 5-Acetylaminosalicylic acid
• NSC 54183-d3
• N-Acetyl Mesalazine-d3
• N-ACETYL MESALAMINE (N-ACETYL-5-AMINO SALICYLIC ACID)
• N-(Acetyl-d3)-5-aminosalicylic Acid
• 3-Carboxyparacetamol-d3
• N-Acetyl Mesalazine
• 3-(Acetylamino)-6-hydroxybenzoic acid

N-acetyl-5-Aminosalicylic Acid

CAS: 51-59-2

Formula: C₉H₉NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 195.1721

Ref: IN-DA00D90L

5-Acetamido-2-hydroxybenzoic acid

CAS: 51-59-2

5-Acetamido-2-hydroxybenzoic acid

Formula: C₉H₉NO₄

Purity: 95%

Color and Shape: solid

Molecular weight: 195.17g/mol

Ref: 54-OR17121

N-Acetyl Mesalamine

CAS: 51-59-2

Formula: C₉H₉NO₄

Color and Shape: Off-White Solid

Molecular weight: 195.17

Ref: 4Z-M-171

5-Acetaminosalicylic Acid

Controlled Product

CAS: 50-86-2, 51-59-2

Color and Shape: Beige Solid

Ref: 86-MM0217.02

5-Acetamido-2-hydroxybenzoic Acid

CAS: 51-59-2

Formula: C₉H₉NO₄

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Yellow powder to crystal

Molecular weight: 195.17

Ref: 3B-A3540

N-Acetyl Mesalazine

CAS: 51-59-2

Formula: C₉H₉NO₄

Molecular weight: 195.17

Ref: ST-EA-CP-M11027

N-Acetyl Mesalazine

CAS: 51-59-2

Stability Hygroscopic
Applications N-Acetyl Mesalazine is an metabolite of Mesalazine. A Salicylic Acid derivative. Inhibitor of recombinant human thiopurine methyltransferase (hTPMT).
References Bondesen, S., et al.: Br. J. Clin. Pharmacol., 25, 269 (1988), Brogden, R., et al.: Drugs, 38, 500 (1989), Jensen, J., et al.: Biochem. Pharmacol., 45, 1201 (1993), Liu, Z., et al.: Drug Metab. Dispos., 23, 246 (1995), Vree, T., et al.: Clin. Drug Invest., 20, 35 (2000),

Formula: C₉H₉NO₄

Color and Shape: Neat

Molecular weight: 195.17

Ref: TR-A168320

N-acetyl-5-Aminosalicylic Acid

CAS: 51-59-2

N-acetyl-5-Aminosalicylic Acid (N-Acetyl mesalazine) is the major metabolite of mesalazine.

Formula: C₉H₉NO₄

Purity: 99.89%

Color and Shape: Solid

Molecular weight: 195.17

Ref: TM-T35708

5-acetamido-2-hydroxybenzoic acid

CAS: 51-59-2

Purity: 98%

Molecular weight: 195.173996

Ref: 10-F622750