CAS 50-89-5

Thymidine

Description:

Thymidine, with the CAS number 50-89-5, is a nucleoside that plays a crucial role in the structure of DNA. It consists of a thymine base attached to a deoxyribose sugar. Thymidine is a key component in the synthesis of DNA, as it pairs with adenine during DNA replication. This compound is typically found in the form of a white crystalline powder and is soluble in water, making it suitable for various biochemical applications. Thymidine is also involved in cellular processes such as DNA repair and synthesis, and it can be phosphorylated to form thymidine monophosphate, which is further converted into thymidine triphosphate (dTTP), an essential building block for DNA polymerization. In laboratory settings, thymidine is often used in research related to cell proliferation and DNA synthesis studies. Additionally, it has been investigated for its potential therapeutic applications in antiviral and anticancer treatments, highlighting its significance in both biological and medical research.

Formula: C₁₀H₁₄N₂O₅

InChI: InChI=1/C10H14N2O5/c1-5-3-12(10(16)11-9(5)15)8-2-6(14)7(4-13)17-8/h3,6-8,13-14H,2,4H2,1H3,(H,11,15,16)/t6-,7-,8+/m1/s1

InChI key: InChIKey=IQFYYKKMVGJFEH-XLPZGREQSA-N

SMILES: O=C1N([C@@H]2O[C@H](CO)[C@@H](O)C2)C=C(C)C(=O)N1

Synonyms:

• (1-[2-Deoxy-beta-D-ribofuranosyl]-5-methyluracil)
• 1-(2-Deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione
• 1-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-methyl-2,4(1H,3H)-pyrimidinedione
• 1-(2-Deoxy-β-D-ribofuranosyl)-5-methyluracil
• 1-(2-deoxy-alpha-D-threo-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione
• 1-(2-deoxy-beta-L-threo-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione
• 1-[(3xi)-2-deoxy-beta-D-glycero-pentofuranosyl]-5-methylpyrimidine-2,4(1H,3H)-dione
• 2'-Deoxythymidine
• 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-beta-D-erythro-pentofuranosyl)-5-methyl-
• 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-beta-D-ribofuranosyl)-5-methyl-
• 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-<span class="text-smallcaps">D</span>-erythro-pentofuranosyl)-5-methyl-
• 2,4(1H,3H)-Pyrimidinedione, 1-(2-deoxy-β-D-erythro-pentofuranosyl)-5-methyl-
• 5-Methyl-2'-deoxyuridine
• 5-Methyldeoxyuridine
• Beta-Thymidine
• DThyd
• Deoxyribothymidine
• Deoxythymidine
• Dexoythymidine
• Nsc 21548
• Thymidin
• Thymine deoxyriboside
• Thymine-2-deoxyribose
• Thymine-2-desoxyriboside
• Thyminedeoxyriboside
• Timidina
• Uridine,2'-deoxy-5-methyl-
• beta-D-Ribofuranoside,thymine-1,2-deoxy-
• dT
• β-<span class="text-smallcaps">D</span>-Ribofuranoside, thymine-1 2-deoxy-
• β-D-Ribofuranoside, thymine-1 2-deoxy-
• β-Thymidine
• Thymidine
• -Thymidine
• 1-(2-DEOXY-BETA-D-RIBOFURANOSYL)THYMINE
• 1-[2-DEOXY-BETA-D-RIBOFURANOSYL]-5-METHYLURACYL
• DTHD
• THYMINE-2'-DEOXYRIBOSIDE
• THYMINE-2-DEOXYRIBOSIDE
• 1-(2-DEOXY-BETA-D-ERYTHRO-PENTOFURANOSYL)-5-METHYL-2,4(1H,3H)-PYRIMIDINEDIONE
• 2'-DEOXYRIBOSYLTHYMINE
• 1-[(2R,4S,5R)-4-HYDROXY-5-(HYDROXYMETHYL)OXOLAN-2-YL]-5-METHYL-PYRIMIDINE-2,4-DIONE

Thymidine

CAS: 50-89-5

Formula: C₁₀H₁₄N₂O₅

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 242.23

Ref: 3B-T0233

Thymidine, 99%

CAS: 50-89-5

Thymidine is used in the syntheses of active pharmaceutical ingredient such as zidovudine. It also pairs with deoxyadenosine in double-stranded deoxyribonucleic acid. It is used to synchronize the cells in G1/early S phase in cell biology. This Thermo Scientific Chemicals brand product was originall

Formula: C₁₀H₁₄N₂O₅

Purity: 99%

Color and Shape: White to pale cream, Powder or crystals or crystalline powder

Molecular weight: 242.23

Ref: 02-A11493

Thymidine

CAS: 50-89-5

Formula: C₁₀H₁₄N₂O₅

Purity: 97%

Color and Shape: Solid, White powder

Molecular weight: 242.231

Ref: 10-F078885

Zidovudine impurity standard

CAS: 25526-94-7, 30516-87-1, 50-89-5, 65-71-4

Zidovudine impurity standard

Color and Shape: Off White Solid

Ref: 47-895

Zidovudine Related Compound D ([1-(2-Deoxy-β-D-ribofuranosyl)]thymine)

CAS: 50-89-5

Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi

Formula: C₁₀H₁₄N₂O₅

Color and Shape: White Crystalline Powder

Molecular weight: 242.09027

Ref: 45-1724543

Thymidine

CAS: 50-89-5

Formula: C₁₀H₁₄N₂O₅

Purity: 97%

Color and Shape: Solid

Molecular weight: 242.2286

Ref: IN-DA001P75

2'-Deoxythymidine

CAS: 50-89-5

2'-Deoxythymidine

Purity: 98%

Color and Shape: Solid

Molecular weight: 242.23g/mol

Ref: 54-OR4884

Thymidine (Zidovudine EP Impurity E, Zidovudine USP Related Compound D)

CAS: 50-89-5

Formula: C₁₀H₁₄N₂O₅

Molecular weight: 242.23

Ref: 4Z-T-581

Thymidine

CAS: 50-89-5

Thymidine

Purity: ≥95%

Molecular weight: 242.23g/mol

Ref: 54-BUP18243

Thymidine

CAS: 50-89-5

Thymidine

Formula: C₁₀H₁₄N₂O₅

Purity: 99%

Color and Shape: off-white powder

Molecular weight: 242.22856g/mol

Ref: 54-BIT2044

Thymidine

CAS: 50-89-5

Formula: C₁₀H₁₄N₂O₅

Purity: 95%~99%

Molecular weight: 242.231

Ref: BP-SBP60036

1-(2-Deoxy-β-D-erythro-pentofuranosyl)-5-methylpyrimidine-2,4(1H,3H)-dione (Thymidine)

CAS: 50-89-5

Color and Shape: Neat

Ref: 86-MM0534.03

Thymidine

CAS: 50-89-5

Thymidine (DThyd) is a cell synchronizing agent and a precursor of deoxyribonucleic acid. Thymidine inhibits DNA synthesis. Cost-effective and quality-assured.

Formula: C₁₀H₁₄N₂O₅

Purity: 99.64% - 99.86%

Color and Shape: White To Off-White Solid Crystalline

Molecular weight: 242.23

Ref: TM-TWP2911

Thymidine

CAS: 50-89-5

Formula: C₁₀H₁₄N₂O₅

Purity: ≥ 99.0%

Color and Shape: White to off-white crystalline powder

Molecular weight: 242.23

Ref: 7W-GE6597

Thymidine-13C,15N2

CAS: 50-89-5

Applications Constituent of deoxyribonucleic acid.
References Levene, L., et al.: J. Bil. Chem. 83, 793 (1929), Tollin, et al.: Nature 217, 1148 (1968)

Formula: C₉₁₃CH₁₄₁₅N₂O₅

Color and Shape: Neat

Molecular weight: 245.21

Ref: TR-T412003

Zidovudine EP Impurity E

CAS: 50-89-5

Formula: C₁₀H₁₄N₂O₅

Molecular weight: 242.23

Ref: ST-EA-CP-Z6005

Thymidine

Controlled Product

CAS: 50-89-5

Applications Constituent of deoxyribonucleic acid.
References Levene, L., et al.: J. Bil. Chem. 83, 793 (1929), Tollin, et al.: Nature 217, 1148 (1968), Redzic, Z., et al.: Neurochem. Res., 34, 566 (2009), Hazra, S., et al.: Biochem., 48, 1256 (2009), Yang, I., et al.: J. Biol. Chem., 284, 191 (2009),

Formula: C₁₀H₁₄N₂O₅

Color and Shape: White To Off-White

Molecular weight: 242.23

Ref: TR-T412000

Thymidine

CAS: 50-89-5

Thymidine, also known as deoxythymidine (dT), is a pyrimidine deoxynucleoside that pairs with deoxyadenosine (dA) in a double stranded DNA. It’s used as a biochemical modulator of antimetabolites such as 5-fluorouracil (5-FU), 1-beta-D-arabinofuranosylcytosine (Cytarabine) and methotrexate (MTX) in cancer therapy. It’s also the enantiomer of telbivudine, an antiviral drug used to treat hepatitis B virus (HBV) infection.

Formula: C₁₀H₁₄N₂O₅

Purity: Min. 99.0 Area-%

Color and Shape: White Powder

Molecular weight: 242.23 g/mol

Ref: 3D-NT02592

Thymidine

CAS: 50-89-5

Thymidine is a nucleoside that is found in cells and is involved in the synthesis of DNA. Thymidine has been shown to inhibit the growth of tumor cells through apoptosis. In addition, thymidine can be used for the treatment of bowel disease by reducing inflammation and increasing the production of mucin. The mechanism by which thymidine exerts its effects on tumor cells is not well understood, but it may involve interactions with dna binding activity and enzyme activities.

Formula: C₁₀H₁₄N₂O₅

Purity: Min. 99 Area-%

Molecular weight: 242.23 g/mol

Ref: 3D-Q-201829

Thymidine extrapure, 99%

CAS: 50-89-5

Formula: C₁₀H₁₄N₂O₅

Purity: min. 99%

Color and Shape: White, Crystalline powder

Molecular weight: 242.23

Ref: SR-20724