CAS 50-91-9
:Floxuridine
Description:
Floxuridine, with the CAS number 50-91-9, is a synthetic antimetabolite and a fluorinated pyrimidine analogue of uridine. It is primarily used in the treatment of certain types of cancer, particularly colorectal cancer and hepatic metastases. The compound functions by inhibiting DNA synthesis, thereby interfering with the proliferation of cancer cells. Floxuridine is typically administered via intravenous injection or intra-arterial infusion, allowing for targeted delivery to tumor sites. Its chemical structure includes a fluorine atom, which enhances its antitumor activity compared to its non-fluorinated counterparts. The substance is known for its potential side effects, which may include myelosuppression, gastrointestinal disturbances, and mucositis. Due to its potent effects and specific application in oncology, floxuridine is classified as a cytotoxic agent and is handled with care in clinical settings. As with many chemotherapeutic agents, monitoring for adverse reactions is essential during treatment.
Formula:C9H11FN2O5
InChI:InChI=1/C9H11FN2O5/c10-4-2-12(9(16)11-8(4)15)7-1-5(14)6(3-13)17-7/h2,5-7,13-14H,1,3H2,(H,11,15,16)/t5-,6-,7?/m1/s1
InChI key:InChIKey=ODKNJVUHOIMIIZ-RRKCRQDMSA-N
SMILES:O=C1N([C@@H]2O[C@H](CO)[C@@H](O)C2)C=C(F)C(=O)N1
Synonyms:- (+)-5-Fluorodeoxyuridine
- 1-(2-Deoxy-β-<span class="text-smallcaps">D</span>-ribofuranosyl)-5-fluorouracil
- 1-(2-Deoxy-β-D-ribofuranosyl)-5-fluorouracil
- 1-(2-deoxy-D-threo-pentofuranosyl)-5-fluoropyrimidine-2,4(1H,3H)-dione
- 1-(2-deoxypentofuranosyl)-5-fluoropyrimidine-2,4(1H,3H)-dione
- 2-Deoxy-5-fluorouridine
- 5-Fluoro-2'-deoxy-β-uridine
- 5-Fluoro-2?Deoxy Uridine
- 5-Fluorouracil 2'-deoxyriboside
- 5-Fluorouracil deoxyriboside
- 5-Fudr
- Deoxyfluorouridine
- FdUrd
- Floxiridina
- Floxuridin
- Floxuridine
- Fudr
- Nsc 26740
- Nsc 27640
- Uridine, 2'-deoxy-5-fluoro-
- 5-Fluoro-2′-deoxyuridine
- 5-Fluoro-2'-deoxyuridine
- 5-Fluoro-2-deoxyuridine
- (+)-5-Fluoro-2?deoxyuridine
- 5-FDU
- 5-FLOXURIDINE
- 2’-deoxy-5-fluoro-uridin
- 1-beta-d-2’-deoxyribofuranosyl-5-flurouracil
- 1beta-D-2'-Deoxyribofuranosyl-5-fluorouracil
- 5-FLUORO-2'-DEOXY-BETA-URIDINE
- 5-FLUORO-1-((2R,4S,5R)-4-HYDROXY-5-HYDROXYMETHYL-TETRAHYDRO-FURAN-2-YL)-1H-PYRIMIDINE-2,4-DIONE
- fluorodeoxyuridine
- 1-(2-DEOXY-BETA-D-RIBOFURANOSYL)-5-FLUOROURACIL
- See more synonyms
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Found 14 products.
2'-Deoxy-5-fluorouridine
CAS:Formula:C9H11FN2O5Purity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:246.195-Fluoro-2'-deoxyuridine, 98+%
CAS:<p>5-Fluoro-2'-deoxyuridine acts as an antiviral and antineoplastic agent. It is also employed for renal function diagnosis. Further, it is used as an experimental anticancer agent, which shows activity against a variety of malignant neoplasms. It is also used as an inhibitor of thymidylate synthetase </p>Formula:C9H11FN2O5Purity:98+%Color and Shape:White to pale cream, PowderMolecular weight:246.19Floxuridine
CAS:<p>Nucleic acids and their salts, whether or not chemically defined; other heterocyclic compounds, nesoi</p>Formula:C9H11FN2O5Color and Shape:White Off-White PowderMolecular weight:246.195-fluoro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-dione
CAS:Formula:C9H11FN2O5Purity:98%Color and Shape:SolidMolecular weight:246.1924Floxuridine
CAS:<p>Floxuridine (FUDR) is an antimetabolite, floxuridine inhibits thymidylate synthase, resulting in disruption of DNA synthesis and cytotoxicity.</p>Formula:C9H11FN2O5Purity:98.92% - 99.96%Color and Shape:SolidMolecular weight:246.195-Fluoro-2'-deoxyuridine
CAS:<p>5-Fluoro-2'-deoxyuridine</p>Formula:C9H11FN2O5Purity:99%Color and Shape: white to off white solidMolecular weight:246.19g/molFloxuridine
CAS:Formula:C9H11FN2O5Purity:(HPLC) ≥ 98.0%Color and Shape:White to off-white powderMolecular weight:246.20Floxuridine
CAS:Controlled Product<p>Applications Floxuridine is an antiviral; antineoplastic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Harris, M., et al.: Biophys. J., 4, 203 (1964),<br></p>Formula:C9H11FN2O5Color and Shape:NeatMolecular weight:246.19Floxuridine-13C,15N2
CAS:Controlled Product<p>Applications Labelled Floxuridine. Antiviral; antineoplastic.<br> Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package<br>References Harris, M., et al.: Biophys. J., 4, 203 (1964),<br></p>Formula:C813CH11F15N2O5Color and Shape:WhiteMolecular weight:249.172'-Deoxy-5-fluorouridine
CAS:<p>2'-Deoxy-5-fluorouridine is a nucleoside analog that inhibits the enzyme ribonucleotide reductase, which is involved in the synthesis of DNA. It has been shown to inhibit the growth of cancer cells and induce apoptosis in vivo. 2'-Deoxy-5-fluorouridine has also been shown to inhibit tumor growth in animal models by inhibiting the production of reactive oxygen species and upregulating tumor suppressor genes, such as p53. This drug also has inhibitory effects on enzymes that are involved in cell proliferation, such as protein kinase C and tyrosine kinases. 2'-Deoxy-5-fluorouridine is metabolized by water vapor, so it must be administered with a humidifier or nebulizer. 2'-Deoxy-5-fluorouridine may cause side effects such as nausea, vomiting, and diarrhea.</p>Formula:C9H11FN2O5Purity:Min. 98 Area-%Color and Shape:White Off-White PowderMolecular weight:246.2 g/mol2′-Deoxy-5-fluorouridine
CAS:Formula:C9H11FN2O5Purity:98%Color and Shape:White powderMolecular weight:246.1945-Fluoro-2-Deoxyuridine extrapure, 98%
CAS:Formula:C9H11FN2O5Purity:min. 98%Color and Shape:White to off white, Crystalline powderMolecular weight:246.20
![5-fluoro-1-[(2R,4S,5R)-4-hydroxy-5-(hydroxymethyl)oxolan-2-yl]-1,2,3,4-tetrahydropyrimidine-2,4-di…](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA0035VM.jpg&w=3840&q=75)
