CAS 500-38-9: Nordihydroguaiaretic acid
Description:Nordihydroguaiaretic acid (NDGA) is a naturally occurring phenolic compound primarily derived from the creosote bush (Larrea tridentata). It is characterized by its antioxidant properties, which are attributed to its ability to scavenge free radicals and inhibit lipid peroxidation. NDGA has a molecular formula of C15H14O4 and features a complex structure that includes two methoxy groups and a catechol moiety. This compound has been studied for its potential therapeutic applications, including anti-inflammatory and anticancer effects, although its use is limited due to potential toxicity and side effects. NDGA is also known to exhibit antimicrobial properties and has been investigated for its role in food preservation. In terms of solubility, it is moderately soluble in organic solvents but less so in water. Due to its unique chemical structure and biological activity, NDGA continues to be of interest in both pharmacological research and industrial applications. However, safety and regulatory considerations are essential when handling this compound.
Formula:C18H22O4
InChI:InChI=1S/C18H22O4/c1-11(7-13-3-5-15(19)17(21)9-13)12(2)8-14-4-6-16(20)18(22)10-14/h3-6,9-12,19-22H,7-8H2,1-2H3
InChI key:InChIKey=HCZKYJDFEPMADG-UHFFFAOYSA-N
SMILES:OC1=CC=C(C=C1O)CC(C)C(C)CC2=CC=C(O)C(O)=C2
- Synonyms:
- 1,4-Bis(3,4-dihydroxyphenyl)-2,3-dimethylbutane
- 4,4'-(2,3-Dimethyl-1,4-butanediyl)bis(pyrocatechol)
- 4,4'-(2,3-Dimethyltetramethylen)dibrenzcatechin
- 4,4'-(2,3-Dimethyltetramethylene)Dipyrocatechol
- 4,4'-(2,3-Dimetiltetrametilen)Dipirocatecol
- 4,4′-(2,3-Dimethyl-1,4-butanediyl)bis[1,2-benzenediol]
- 4-[4-(3,4-Dihydroxyphenyl)-2,3-dimethylbutyl]benzene-1,2-diol
- Butane, 1,4-bis(3,4-dihydroxyphenyl)-2,3-dimethyl-
- Dihydronorguaiaretic acid
- Dinorguaiaretic acid, dihydro-
- See more synonyms
- Ndga
- Nordihydroguaiaretic acid
- Nordihydroguaiaretinsaeure
- Norguaiaretic acid, dihydro-
- Nsc 4291
- Pyrocatechol, 4,4'-(2,3-dimethyltetramethylene)di-
- β,γ-Dimethyl-α,δ-bis(3,4-dihydroxyphenyl)butane
- 1,2-Benzenediol, 4,4′-(2,3-dimethyl-1,4-butanediyl)bis-
- 4,4'-[(2R,3R)-2,3-dimethylbutane-1,4-diyl]dibenzene-1,2-diol
- NDGA, Larrea divaricata
- 4,4'-[(2S,3S)-2,3-dimethylbutane-1,4-diyl]dibenzene-1,2-diol

Nordihydroguaiaretic acid, 97%
Ref: 02-L03149
1g | 80.00 € | ||
5g | To inquire |

Nordihydroguaiaretic acid
Ref: 11-6135
100mg | 55.00 € |

Nordihydroguaiaretic acid
- Polyols
- Phenylpropanoids
- Natural Products and Phytochemicals by Botanical Origin
- Phytochemicals
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- Enzyme Activators and Inhibitors
- APIs for research and impurities
- Enzymes
- Other Inhibitors
- Cancer Research
- Biochemicals and Reagents
- Cellular and Molecular Biology
- Oxygen (O) Containing Building Blocks
- Nutrition Research
Ref: IN-DA003TAG
1g | 208.00 € | ||
5g | To inquire | ||
100mg | 68.00 € | ||
250mg | 114.00 € |

Ref: 54-BUP14743
50mg | 56.00 € | ||
100mg | 77.00 € | ||
500mg | 203.00 € |

Ref: 54-OR1023910
1g | 209.00 € | ||
100mg | 51.00 € | ||
250mg | 80.00 € |

Nordihydroguaiaretic acid, 95%
Ref: AC-37630
1g | To inquire | ||
5g | To inquire | ||
500mg | To inquire |

GB 5009.32-2016 Antioxidants Mixture 161 1000 mg/L in Acetonitrile
Controlled ProductRef: 04-A50000161AL
1ml | 579.00 € |

Ref: 04-C15644200
50mg | To inquire |

Nordihydroguaiaretic Acid
- Building Blocks
- Polyols
- Phenylpropanoids
- Natural Products and Phytochemicals by Botanical Origin
- See more categories
- Phytochemicals
- Enzyme Activators and Inhibitors
- Enzymes
- Cancer Research
- Biochemicals and Reagents
- Cellular and Molecular Biology
- Microbiology Antibodies
- Oxygen (O) Containing Building Blocks
- Nutrition Research
Ref: 3B-D0800
1g | 79.00 € | ||
5g | 333.00 € |

Nordihydroguaiaretic acid
Ref: 7W-GE5483
1g | 87.00 € |

Nordihydroguaiaretic acid
- Inhibitors
- Ferroptosis
- Lipoxygenase
- Autophagy
- See more categories
- Oxidation-Reduction
Ref: TM-TJS2190
50mg | 39.00 € | ||
100mg | 49.00 € | ||
500mg | 131.00 € | ||
1mL*10mM (DMSO) | 57.00 € |

Nordihydroguaiaretic acid
Ref: 5G-82880
50mg | 185.00 € | ||
250mg | 678.00 € | ||
500mg | 1,233.00 € | ||
1000mg | 2,312.00 € |

Nordihydro Guaiaretic Acid (mixture of diastereomers)
Controlled ProductRef: TR-N673000
50mg | 94.00 € | ||
250mg | 347.00 € |

Nordihydroguaiaretic acid
Ref: 3D-N-8500
5g | To inquire | ||
10g | To inquire | ||
25g | To inquire | ||
50g | To inquire | ||
2500mg | To inquire | ||
-Unit-gg | To inquire |

Nordihydroguaiaretic acid - mixture of diastereomers
Ref: 3D-FN26437
5g | 228.00 € | ||
10g | 356.00 € | ||
1kg | 6,920.00 € | ||
25g | 660.00 € | ||
50g | 1,042.00 € |