CAS 500-62-9

Yangonin

Description:

Yangonin is a natural compound classified as a benzopyran derivative, primarily found in the plant species *Piper methysticum*, commonly known as kava. It is recognized for its psychoactive properties and has been studied for its potential therapeutic effects, particularly in relation to anxiety and stress relief. Yangonin exhibits a unique chemical structure that contributes to its biological activity, including interactions with the endocannabinoid system. The compound is known for its lipophilic nature, which allows it to easily cross biological membranes. In terms of solubility, yangonin is generally soluble in organic solvents but has limited solubility in water. Its pharmacological profile suggests that it may influence neurotransmitter systems, although further research is needed to fully elucidate its mechanisms of action and potential health benefits. As with many natural products, the safety and efficacy of yangonin in clinical applications require careful consideration and further investigation.

Formula: C₁₅H₁₄O₄

InChI: InChI=1S/C15H14O4/c1-17-12-6-3-11(4-7-12)5-8-13-9-14(18-2)10-15(16)19-13/h3-10H,1-2H3/b8-5+

InChI key: InChIKey=XLHIYUYCSMZCCC-VMPITWQZSA-N

SMILES: C(=C/C1=CC=C(OC)C=C1)\C2=CC(OC)=CC(=O)O2

Synonyms:

• (E)-4-Methoxy-6-[2-(4-methoxyphenyl)ethenyl]-2H-pyran-2-one
• 2H-Pyran-2-one, 4-methoxy-6-(p-methoxystyryl)-
• 2H-Pyran-2-one, 4-methoxy-6-[(1E)-2-(4-methoxyphenyl)ethenyl]-
• 2H-Pyran-2-one, 4-methoxy-6-[2-(4-methoxyphenyl)ethenyl]-, (E)-
• 2H-pyran-2-one, 4-methoxy-6-[(E)-2-(4-methoxyphenyl)ethenyl]-
• 4-Methoxy-6-[(1E)-2-(4-methoxyphenyl)ethenyl]-2H-pyran-2-one
• 4-Methoxy-6-[(E)-2-(4-methoxyphenyl)vinyl]-2H-pyran-2-on
• 4-Methoxy-6-[(E)-2-(4-methoxyphenyl)vinyl]-2H-pyran-2-one
• 4-Methoxy-6-[b-(p-anisyl)vinyl]-a-pyrone
• 4-Méthoxy-6-[(E)-2-(4-méthoxyphényl)éthènyl]-2H-pyran-2-one
• 5-Hydroxy-3-methoxy-7-(p-methoxyphenyl)-2,4,6-heptatrienoic Acid d-Lactone
• 6-(p-Methoxystyryl)-4-methoxy-a-pyrone

Yangonin

CAS: 500-62-9

Yangonin analytical standard provided with chromatographic purity, to be used as reference material for qualitative determination.

Formula: C₁₅H₁₄O₄

Purity: (HPLC) ≥95%

Color and Shape: Powder

Molecular weight: 258.27

Ref: 11-4989

Yangonin

CAS: 500-62-9

Formula: C₁₅H₁₄O₄

Molecular weight: 258.27

Ref: 7W-GY4353

yangonin

CAS: 500-62-9

yangonin

Purity: ≥98%

Molecular weight: 258.27g/mol

Ref: 54-BUP05071

Yangonin

CAS: 500-62-9

Formula: C₁₅H₁₄O₄

Purity: 95%~99%

Molecular weight: 258.273

Ref: BP-BP1460

yangonin

CAS: 500-62-9

Yangonin (Y100550) is a novel CB1 receptor ligand with affinity for human recombinant CB1 receptors.

Formula: C₁₅H₁₄O₄

Purity: 98.82% - 99.55%

Color and Shape: Pale Yellow Powder

Molecular weight: 258.27

Ref: TM-T3S0738

Yangonin

CAS: 500-62-9

Formula: C₁₅H₁₄O₄

Molecular weight: 258.27

Ref: 4Z-Y-007001

Yangonin

CAS: 500-62-9

Lactone

Formula: C₁₅H₁₄O₄

Purity: ≥ 95.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 258.27

Ref: 5G-89293

Yangonin

Controlled Product

CAS: 500-62-9

Applications A lactone isolated from the Kava plant (Piper methysticum). The active constituents of Kava are a group of approx. 18 compounds collectively referred to as kavalactones or kava pyrones. Kawain, dihydrokawain, methysticin, dihydromethysticin, yangonin, and desmethoxyyangonin are the six major kavalactones. Kava beverages and other preparations are known to be anxiolytic and are used for anxiety disorders. Dietary supplements containing the root of the kava shrub have been implicated in several cases of liver toxicity in humans, including several who required liver transplants after using kava supplements.
References Keledjian, J., et al.: J. Pharm. Sci., 77, 1003 (1988), Clouatre, D., et al.: Toxicol. Lett., 150, 85 (2004), Mathews, J., et al.: Drug Metab. Dispos., 33, 1555 (2005), Clayton, N., et al.: Exp. Toxicol. Pathol., 58, 223 (2007),

Formula: C₁₅H₁₄O₄

Color and Shape: Neat

Molecular weight: 258.27

Ref: TR-Y100550

Yangonin

CAS: 500-62-9

Yangonin is a kavalactone, which is a type of compound found in the roots of the Piper methysticum plant, commonly known as kava. This product is derived through the extraction of kavalactones from the kava root, a process that isolates its active psychoactive components. Yangonin is known for its interaction with the brain's neuroreceptor systems, particularly the cannabinoid CB1 receptors. This interaction may contribute to its psychoactive effects, influencing mood and perception.

Formula: C₁₅H₁₄O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 258.27 g/mol

Ref: 3D-FY137901

Yangonin-d3

Controlled Product

CAS: 500-62-9

Applications Isotope labelled analog of Yangonin (Y100550), a lactone isolated from the Kava plant (Piper methysticum). The active constituents of Kava are a group of approx. 18 compounds collectively referred to as kavalactones or kava pyrones. Kawain, dihydrokawain, methysticin, dihydromethysticin, yangonin, and desmethoxyyangonin are the six major kavalactones. Kava beverages and other preparations are known to be anxiolytic and are used for anxiety disorders. Dietary supplements containing the root of the kava shrub have been implicated in several cases of liver toxicity in humans, including several who required liver transplants after using kava supplements.
References Keledjian, J., et al.: J. Pharm. Sci., 77, 1003 (1988), Clouatre, D., et al.: Toxicol. Lett., 150, 85 (2004), Mathews, J., et al.: Drug Metab. Dispos., 33, 1555 (2005), Clayton, N., et al.: Exp. Toxicol. Pathol., 58, 223 (2007),

Formula: C₁₅H₁₁D₃O₄

Color and Shape: Neat

Molecular weight: 261.29

Ref: TR-Y100552