CAS 500-65-2

Rhapontigenin

Description:

Rhapontigenin is a naturally occurring flavonoid, specifically a type of chalcone, which is primarily found in various plants, including rhubarb. It is characterized by its chemical structure, which includes a chromone backbone with hydroxyl and methoxy substituents. Rhapontigenin exhibits a range of biological activities, including antioxidant, anti-inflammatory, and potential anticancer properties, making it of interest in pharmacological research. Its molecular formula is typically represented as C15H12O5, and it has a relatively low molecular weight. The compound is soluble in organic solvents but has limited solubility in water. Rhapontigenin is often studied for its effects on various cellular pathways and its potential therapeutic applications, particularly in the context of chronic diseases. Additionally, it may contribute to the health benefits associated with the consumption of rhubarb and other plants containing this flavonoid. As research continues, the full scope of its biological effects and mechanisms of action is still being explored.

Formula: C₁₅H₁₄O₄

InChI: InChI=1/C15H14O4/c1-19-15-5-4-10(8-14(15)18)2-3-11-6-12(16)9-13(17)7-11/h2-9,16-18H,1H3/b3-2+

InChI key: InChIKey=PHMHDRYYFAYWEG-NSCUHMNNSA-N

SMILES: C(=C/C1=CC(O)=C(OC)C=C1)\C2=CC(O)=CC(O)=C2

Synonyms:

• 1,3-Benzenediol, 5-[(1E)-2-(3-hydroxy-4-methoxyphenyl)ethenyl]-
• 1,3-Benzenediol, 5-[2-(3-hydroxy-4-methoxyphenyl)ethenyl]-, (E)-
• 1,3-benzenediol, 5-[(E)-2-(3-hydroxy-4-methoxyphenyl)ethenyl]-
• 3,3′,5-Stilbenetriol, 4′-methoxy-, (E)-
• 5-[(1E)-2-(3-Hydroxy-4-methoxyphenyl)ethenyl]-1,3-benzenediol
• 5-[(E)-2-(3-Hydroxy-4-methoxyphenyl)vinyl]benzene-1,3-diol
• 5-[(E)-2-(3-hydroxy-4-methoxyphenyl)ethenyl]benzene-1,3-diol
• Pontigenin
• Prontigenin
• Protigenin
• Rhapontin aglycone
• Rhapontin genin
• rhapontigenin USP/EP/BP
• 5-[2-(3-hydroxy-4-methoxyphenyl)ethenyl]benzene-1,3-diol
• 3,3',5-Trihydroxy-4'-methoxy-trans-stilbene
• (E)-4'-Methoxy-3,3',5-stilbenetriol
• -5-(3-Hydroxy-4-methoxystyryl)
• trans-1-(3,5-Dihydroxyphenyl)-2-(3-hydroxy-4-methoxyphenyl)ethylene
• rhapontigenin
• Rhapontigenin &gt
• 3-benzenediol
• (E)-5-(3-Hydroxy-4-Methoxystyryl)benzene-1,3-diol
• 5-[(1E)-2-(3-hydroxy-4-methoxyphenyl)ethenyl]-1
• 5-[(1E)-2-(3-HYDROXY-4-METHOXYPHENYL)ETHENYL]-1;3-BENZENEDIOL

Rhapontigenin

CAS: 500-65-2

Rhapontigenin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₁₅H₁₄O₄

Purity: (HPLC) ≥98%

Color and Shape: Powder

Molecular weight: 258.27

Ref: 11-4971S

Rhapontigenin

CAS: 500-65-2

Formula: C₁₅H₁₄O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 258.2693

Ref: IN-DA003C0U

Rhapontigenin

CAS: 500-65-2

Rhapontigenin

Formula: C₁₅H₁₄O₄

Purity: ≥98%

Molecular weight: 258.27

Ref: 54-BUP00740

Rhapontigenin

CAS: 500-65-2

Formula: C₁₅H₁₄O₄

Molecular weight: 258.27

Ref: 7W-GY4034

Rhapontigenin (Standard)

CAS: 500-65-2

Rhapontigenin (Standard) is a reference standard for research and analysis in studies involving Rhapontigenin. Rhapontigenin (Protigenin) is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50: 400 nM), an aryl hydrocarbon hydroxylase which activates polycyclic aromatic hydrocarbons that act as procarcinogens. Rhapontigenin is a natural analog of resveratrol with antioxidant and anti-cancer activity. At higher concentrations, rhapontigenin inhibits the proliferation of HL-60R and HepG2 cancer cell lines (IC50: 48 μM).

Formula: C₁₅H₁₄O₄

Color and Shape: Solid

Molecular weight: 258.27

Ref: TM-TMSM-1273

Rhapontigenin

CAS: 500-65-2

Rhapontigenin has antioxidative, antihyperlipidemic, antifungal and anticancer activities. Rhapontigenin inhibits HIF-1α accumulation and angiogenesis in PC-3 prostate cancer cells, suppresses breast cancer cell migration and invasion, which is involved in inhibiting the PI3K-dependent Rac1 signaling pathway. Rhapontigenin exhibits dose-dependent inhibition of tyrosinase activity and melanin synthesis in B16F10 melanoma cells.

Formula: C₁₅H₁₄O₄

Purity: 95%~99%

Color and Shape: Cryst.

Molecular weight: 258.273

Ref: BP-BP1671

Rhapontigenin

CAS: 500-65-2

Formula: C₁₅H₁₄O₄

Purity: >98.0%(GC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 258.27

Ref: 3B-R0089

Rhapontigenin

CAS: 500-65-2

Rhapontigenin (Protigenin) is a mechanism-based, selective inactivator of cytochrome P450 1A1 (IC50: 400 nM), an aryl hydrocarbon hydroxylase which activates

Formula: C₁₅H₁₄O₄

Purity: 99.36% - 99.88%

Color and Shape: Solid

Molecular weight: 258.27

Ref: TM-T3776

Rhapontigenin

CAS: 500-65-2

(E)-5-(3-Hydroxy-4-methoxystyryl)benzene-1,3-diol

Formula: C₁₅H₁₄O₄

Purity: 98%

Molecular weight: 258.27

Ref: IN-DG161469

Rhapontigenin

CAS: 500-65-2

Polyphenol

Formula: C₁₅H₁₄O₄

Purity: ≥ 98.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 258.27

Ref: 5G-83903

Rhapontigenin

CAS: 500-65-2

Rhapontigenin is an anti-cancer compound that has been shown to inhibit the growth of colorectal adenocarcinoma cells. It is a natural product that is found in plants and has been shown to have a variety of biological effects such as inhibiting the growth of opportunistic fungi, acting as a chemical inhibitor, and being toxic to cancer cells. Rhapontigenin has been shown to inhibit mitochondrial membrane potential and signal pathways in experimental models. This compound also has potential as an autoimmune disease treatment due to its inhibition of immune cell proliferation.

Formula: C₂₅H₁₄O₄

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 258.27 g/mol

Ref: 3D-FR74524

RHAPONTIGENIN

CAS: 500-65-2

Purity: 98%

Molecular weight: 258.2730103

Ref: 10-F795442

Rhapontigenin

Controlled Product

CAS: 500-65-2

Formula: C₁₅H₁₄O₄

Color and Shape: Neat

Molecular weight: 258.269

Ref: TR-R316003