CAS 5006-66-6

6-Hydroxynicotinic acid

Description:

6-Hydroxynicotinic acid, with the CAS number 5006-66-6, is a derivative of nicotinic acid, characterized by the presence of a hydroxyl group at the 6-position of the pyridine ring. This compound is a white to off-white crystalline solid that is soluble in water and polar organic solvents, reflecting its polar functional groups. It exhibits properties typical of carboxylic acids, including the ability to donate protons in solution, which contributes to its acidity. The hydroxyl group enhances its potential for hydrogen bonding, influencing its reactivity and interactions with other molecules. 6-Hydroxynicotinic acid is of interest in various fields, including medicinal chemistry, where it may serve as a precursor for the synthesis of pharmaceuticals or as a ligand in coordination chemistry. Additionally, it has been studied for its potential biological activities, including effects on the central nervous system and its role in metabolic pathways. Overall, its unique structural features make it a valuable compound for research and application in various chemical contexts.

Formula: C₆H₅NO₃

InChI: InChI=1S/C6H5NO3/c8-5-2-1-4(3-7-5)6(9)10/h1-3H,(H,7,8)(H,9,10)

InChI key: InChIKey=BLHCMGRVFXRYRN-UHFFFAOYSA-N

SMILES: C(O)(=O)C=1C=CC(=O)NC1

Synonyms:

• 1,6-Dihydro-6-oxo-3-pyridinecarboxylic acid
• 2-Hydroxy-5-Pyridinecarboxylic Acid
• 2-Hydroxy-5-carboxypyridine
• 2-Hydroxypyridine-5-carboxylic acid
• 2-Oxopyridine-5-carboxylic acid
• 2-Pyridone-5-carboxylic acid
• 3-Pyridinecarboxylic acid, 1,6-dihydro-6-oxo-
• 5-Carboxy-2-pyridone
• 6-Hydroxy Nicotinic Acid
• 6-Hydroxyniacin
• 6-Hydroxypyridine-3-carboxylic acid
• 6-Oxo-1,6-Dihydropyridine-3-Carboxylate
• 6-Oxo-1,6-dihydro-pyridine-3-carboxylic acid
• 6-Oxonicotinic Acid
• NSC 35054
• NSC 53377
• NSC 8620
• Nicotinic acid, 1,6-dihydro-6-oxo-
• Nicotinic acid, 6-hydroxy-

6-Hydroxynicotinic Acid

CAS: 5006-66-6

Formula: C₆H₅NO₃

Purity: >97.0%(GC)(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 139.11

Ref: 3B-H0633

6-Hydroxynicotinic acid, 98%

CAS: 5006-66-6

Metabolite of nicotinamide. Stimulates adrenocortical secretion This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference

Formula: C₆H₅NO₃

Purity: 98%

Color and Shape: Powder, Pale cream to cream to brown

Molecular weight: 139.11

Ref: 02-A15802

6-Hydroxynicotinic Acid

CAS: 5006-66-6

Compounds containing an unfused pyridine ring in the structure, nesoi

Formula: C₆H₅NO₃

Color and Shape: Powder

Molecular weight: 139.02694

Ref: 45-1327408

6-Hydroxynicotinic acid

CAS: 5006-66-6

Formula: C₆H₅NO₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 139.1088

Ref: IN-DA003N8T

6-Hydroxynicotinic acid

CAS: 5006-66-6

Formula: C₆H₅NO₃

Molecular weight: 139.11

Ref: 7W-GK0244

6-Hydroxynicotinic acid

CAS: 5006-66-6

6-Hydroxynicotinic acid

Purity: ≥98%

Molecular weight: 139.11g/mol

Ref: 54-BUP19483

6-Hydroxynicotinic acid

CAS: 5006-66-6

Formula: C₆H₅NO₃

Purity: 98.0%

Color and Shape: Solid

Molecular weight: 139.11

Ref: 10-F009265

6-Hydroxynicotinic Acid

Controlled Product

CAS: 5006-66-6

Formula: C₆H₅NO₃

Color and Shape: Neat

Molecular weight: 139.11

Ref: 86-MM0553.15

Nicotinic acid-6-hydroxy

CAS: 5006-66-6

Formula: C₆H₅NO₃

Color and Shape: Neat

Molecular weight: 139.11

Ref: 04-C15521080

6-Hydroxynicotinic acid

CAS: 5006-66-6

6-Hydroxynicotinic acid

Formula: C₆H₅NO₃

Purity: 98%

Color and Shape: grey solid

Molecular weight: 139.11g/mol

Ref: 54-OR5072

6-Hydroxynicotinic acid

CAS: 5006-66-6

6-Hydroxynicotinic acid (6-Hydroxypyridine-3-carboxylic acid) is used of NMR or GC-MS for the diagnosis of Pseudomonas aeruginosa in urinary tract infection.

Formula: C₆H₅NO₃

Purity: 98.98%

Color and Shape: Solid

Molecular weight: 139.11

Ref: TM-T4816

6-Hydroxy Nicotinic Acid

Controlled Product

CAS: 5006-66-6

Formula: C₆H₅NO₃

Color and Shape: Neat

Molecular weight: 139.11

Ref: TR-H948545

6-Hydroxynicotinic acid

CAS: 5006-66-6

6-Hydroxynicotinic acid is a nicotinic acid analogue that has been shown to inhibit bacterial growth, with the exception of Bacillus subtilis. It has been shown to be specific for bacterial nicotinamide adenine dinucleotide (NAD) reductase and NAD+ kinase enzymes, which are involved in the biosynthesis of nicotinamide adenine dinucleotide phosphate (NADP). 6-Hydroxynicotinic acid binds to these enzymes and prevents them from carrying out their normal reactions, leading to decreased ATP production. In vitro assays have also demonstrated that 6-hydroxynicotinic acid inhibits human epidermal growth factor receptor (EGFR) tyrosine phosphorylation, thereby inhibiting its signalling pathway.

Formula: C₆H₅NO₃

Purity: Min. 95%

Color and Shape: White Powder

Molecular weight: 139.11 g/mol

Ref: 3D-FH02538