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CAS 50293-90-8

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Levalbuterol hydrochloride

Description:
Levalbuterol hydrochloride is a selective beta-2 adrenergic agonist primarily used as a bronchodilator in the treatment of asthma and chronic obstructive pulmonary disease (COPD). It is the R-enantiomer of albuterol, which means it has a specific three-dimensional arrangement that enhances its therapeutic effects while minimizing side effects. The substance appears as a white to off-white crystalline powder and is soluble in water, making it suitable for inhalation formulations. Levalbuterol acts by stimulating beta-2 adrenergic receptors in the bronchial smooth muscle, leading to relaxation and dilation of the airways, thus improving airflow and alleviating symptoms of bronchospasm. Its pharmacokinetics indicate a rapid onset of action, typically within minutes, with a duration of effect that can last several hours. Common side effects may include tremors, nervousness, and increased heart rate, although these are generally less pronounced compared to racemic albuterol. Levalbuterol is often preferred in patients who experience adverse effects from other beta-agonists, providing effective relief with a more favorable side effect profile.
Formula:C13H21NO3·ClH
InChI:InChI=1S/C13H21NO3.ClH/c1-13(2,3)14-7-12(17)9-4-5-11(16)10(6-9)8-15;/h4-6,12,14-17H,7-8H2,1-3H3;1H/t12-;/m0./s1
InChI key:InChIKey=OWNWYCOLFIFTLK-YDALLXLXSA-N
SMILES:[C@@H](CNC(C)(C)C)(O)C1=CC(CO)=C(O)C=C1.Cl
Synonyms:
  • (-)-Salbutamol hydrochloride
  • (R)-4-(2-(tert-Butylamino)-1-hydroxyethyl)-2-(hydroxymethyl)phenol hydrochloride
  • (R)-Salbutamol hydrochloride
  • 1,3-Benzenedimethanol, α<sup>1</sup>-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-, hydrochloride (1:1), (α<sup>1</sup>R)-
  • 1,3-Benzenedimethanol, α<sup>1</sup>-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-, hydrochloride, (R)-
  • 1,3-Benzenedimethanol, α<sup>1</sup>-[[(1,1-dimethylethyl)amino]methyl]-4-hydroxy-, hydrochloride, (α<sup>1</sup>R)-
  • Levalbuterol Hydrochloride
  • Levalbuterol hcl
  • Levosalbutamol hydrochloride
  • Xopenex
  • See more synonyms
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