CAS 503-49-1

3-Hydroxy-3-methylglutaric acid

Description:

3-Hydroxy-3-methylglutaric acid, also known as HMG acid, is an organic compound characterized by its hydroxyl and carboxylic acid functional groups. It is a colorless to pale yellow solid that is soluble in water and polar organic solvents. The molecular structure features a branched chain with a hydroxyl group attached to the central carbon, contributing to its reactivity and potential biological activity. HMG acid plays a significant role in metabolic pathways, particularly in the synthesis of mevalonate, which is a precursor for cholesterol and other isoprenoids. It is also involved in the biosynthesis of certain amino acids and is important in various biochemical processes. The compound has been studied for its potential therapeutic applications, including its role in cholesterol-lowering treatments and as a supplement in certain metabolic disorders. Due to its biological significance, 3-hydroxy-3-methylglutaric acid is of interest in both pharmaceutical and nutritional research.

Formula: C₆H₁₀O₅

InChI: InChI=1S/C6H10O5/c1-6(11,2-4(7)8)3-5(9)10/h11H,2-3H2,1H3,(H,7,8)(H,9,10)

InChI key: InChIKey=NPOAOTPXWNWTSH-UHFFFAOYSA-N

SMILES: C(C(CC(O)=O)(C)O)C(O)=O

Synonyms:

• 3-(Hydroxymethyl)Pentanedioic Acid
• 3-Hydroxy-3-methylpentanedioic acid
• 3-Methyl-3-hydroxyglutaric acid
• 3-Methyl-3-hydroxypentanedioic acid
• Cb 337
• Dicrotalic acid
• Glutaric acid, 3-hydroxy-3-methyl-
• Lipoglutaren
• Medroglutaric acid
• Meglutol
• Mevalon
• NSC 361411
• Pentanedioic acid, 3-hydroxy-3-methyl-
• β-Hydroxy-β-methylglutaric acid

3-Hydroxy-3-methylglutaric Acid

CAS: 503-49-1

Formula: C₆H₁₀O₅

Purity: >95.0%(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 162.14

Ref: 3B-H0436

3-Hydroxy-3-Methylpentanedioic Acid

CAS: 503-49-1

3-Hydroxy-3-Methylpentanedioic Acid

Formula: C₆H₁₀O₅

Purity: 98%

Molecular weight: 162.14

Ref: 54-OR1027881

Meglutol

CAS: 503-49-1

Meglutol

Formula: C₆H₁₀O₅

Purity: 99.5%

Molecular weight: 162.14

Ref: 54-BUP14722

3-Hydroxy-3-methyl-d3-pentanedioic Acid

CAS: 503-49-1, 59060-36-5

Formula: HOOCCH₂C(OH)(CD₃)CH₂COOH

Purity: 99 atom % D

Color and Shape: White-Pale Yellow Solid

Molecular weight: 165.07165

Ref: 3U-D3772

3-hydroxy-3-methylpentanedioic acid

CAS: 503-49-1

Formula: C₆H₁₀O₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 162.1406

Ref: IN-DA00I90Y

3-Hydroxy-3-methylpentanedioic acid

CAS: 503-49-1

Formula: C₆H₁₀O₅

Purity: 95%~99%

Molecular weight: 162.141

Ref: BP-BP4248

3-Hydroxy-3-methylpentane-1,5-dioic Acid

Controlled Product

CAS: 503-49-1

Applications 3-Hydroxy-3-methylpentane-1,5-dioic Acid (cas# 503-49-1) is a compound useful in organic synthesis.

Formula: C₆H₁₀O₅

Color and Shape: Neat

Molecular weight: 162.14

Ref: TR-H948263

Meglutol

CAS: 503-49-1

Meglutol, a cholesterol and triglyceride reducing antilipemic, hinders key enzymes in cholesterol biosynthesis.

Formula: C₆H₁₀O₅

Purity: 99.73% - 99.94%

Color and Shape: Solid

Molecular weight: 162.1406

Ref: TM-T1664

3-Hydroxy-3-methylglutaric acid

CAS: 503-49-1

Formula: C₆H₁₀O₅

Purity: (TLC) ≥ 95%

Color and Shape: White to off-white powder

Molecular weight: 162.14

Ref: 7W-GK7523

3-Hydroxy-3-methylpentanedioic acid

CAS: 503-49-1

Formula: C₆H₁₀O₅

Color and Shape: Solid

Molecular weight: 162.14

Ref: BE-MU-8299

Meglutol

CAS: 503-49-1

3-Hydroxy-3-methylpentanedioic acid

Formula: C₆H₁₀O₅

Purity: 98%

Molecular weight: 162.14

Ref: IN-DG87230

3-HYDROXY-3-METHYLPENTANE-1

CAS: 503-49-1

Formula: C₆H₁₀O₅

Purity: 98%

Molecular weight: 162.141

Ref: 10-F538666

Meglutol (Standard)

CAS: 503-49-1

Meglutol (Standard) is a reference standard for research and analysis in studies involving Meglutol. Meglutol (3-Hydroxy-3-methylglutaric acid) is an antilipemic agent which lowers cholesterol, triglycerides, serum beta-lipoproteins and phospholipids. It acts by interfering with the enzymatic steps involved in the conversion of acetate to hydroxymethyl glutaryl coenzyme A as well as inhibiting the activity of HYDROXYMETHYLGLUTARYL COA REDUCTASES which is the rate-limiting enzyme in the biosynthesis of cholesterol.

Formula: C₆H₁₀O₅

Molecular weight: 162.1406

Ref: TM-TMSM-3695

3-Hydroxy-3-methylglutaric acid

CAS: 503-49-1

3-Hydroxy-3-methylglutaric acid is an organic acid that is a valuable intermediate in the chemical production of epidermal growth factor. 3-Hydroxy-3-methylglutaric acid also has been shown to be useful as a reagent for the detection of bacterial strains, including E. coli, Salmonella enterica, and Pseudomonas aeruginosa. The enzyme activities of 3-hydroxy-3-methylglutaric acid are not well understood, but it has been shown to have effects on congestive heart failure and bowel disease. 3-Hydroxy-3-methylglutaric acid may be used in the treatment of inflammatory bowel disease due to its ability to inhibit certain enzymes responsible for inflammation and pain. The long term toxicity and symptoms associated with 3-hydroxy-3-methylglutaric acid have not yet been studied, but it has been shown to have no effect on cardiac function

Formula: C₆H₁₀O₅

Purity: Min. 95%

Molecular weight: 162.14 g/mol

Ref: 3D-FH57974