CAS 5041-81-6

Isoliquiritin

Description:

Isoliquiritin is a flavonoid compound primarily derived from the roots of Glycyrrhiza glabra, commonly known as licorice. It is characterized by its chemical structure, which includes a flavanone backbone, contributing to its various biological activities. Isoliquiritin exhibits antioxidant properties, helping to neutralize free radicals and reduce oxidative stress. Additionally, it has been studied for its potential anti-inflammatory, anti-cancer, and neuroprotective effects, making it of interest in pharmacological research. The compound is soluble in organic solvents and has a relatively low molecular weight, which facilitates its absorption in biological systems. Isoliquiritin is also noted for its ability to modulate certain signaling pathways, which may contribute to its therapeutic effects. Its safety profile is generally favorable, but further studies are needed to fully understand its pharmacokinetics and long-term effects. Overall, isoliquiritin represents a promising natural product with potential applications in health and medicine.

Formula: C₂₁H₂₂O₉

InChI: InChI=1/C21H22O9/c22-10-17-18(26)19(27)20(28)21(30-17)29-13-5-1-11(2-6-13)3-8-15(24)14-7-4-12(23)9-16(14)25/h1-9,17-23,25-28H,10H2/b8-3+/t17-,18-,19+,20-,21-/m1/s1

InChI key: InChIKey=YNWXJFQOCHMPCK-LXGDFETPSA-N

SMILES: O([C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O)C2=CC=C(/C=C/C(=O)C3=C(O)C=C(O)C=C3)C=C2

Synonyms:

• (2E)-1-(2,4-Dihydroxyphenyl)-3-[4-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)phenyl]-2-propen-1-one
• 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-(4-(beta-D-glucopyranosyloxy)phenyl)-, (2E)-
• 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-[4-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)phenyl]-, (2E)-
• 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-[4-(β-<span class="text-smallcaps">D</span>-glucopyranosyloxy)phenyl]-, (E)-
• 2′,4,4′-Trihydroxychalcone 4-(β-<span class="text-smallcaps">D</span>-glucopyranoside)
• Chalcone, 2′,4,4′-trihydroxy-, 4-β-<span class="text-smallcaps">D</span>-glucopyranoside
• Isoliquiritin
• Isoliquiritoside
• 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-[4-(β-D-glucopyranosyloxy)phenyl]-, (2E)-
• 2-Propen-1-one, 1-(2,4-dihydroxyphenyl)-3-[4-(β-D-glucopyranosyloxy)phenyl]-, (E)-
• (2E)-1-(2,4-Dihydroxyphenyl)-3-[4-(β-D-glucopyranosyloxy)phenyl]-2-propen-1-one
• Chalcone, 2′,4,4′-trihydroxy-, 4-β-D-glucopyranoside
• (E)-1-(2,4-Dihydroxyphenyl)-3-[4-(β-D-glucopyranosyloxy)phenyl]-2-propen-1-one
• [(E)-2',4'-Dihydroxychalcone-4-yl]β-D-glucopyranoside
• 4-[(1E)-3-(2,4-dihydroxyphenyl)-3-oxoprop-1-en-1-yl]phenyl beta-D-glucopyranoside
• Aids-004475
• 2',4,4'-Trihydroxychalcone 4-beta-D-glucopyranoside
• 2',4,4'-Trihydroxychalcone 4-(beta-D-glucopyranoside)
• neoisoliquritin

Isoliquiritin

CAS: 5041-81-6

Formula: C₂₁H₂₂O₉

Purity: >98.0%(HPLC)

Color and Shape: White to Yellow powder to crystal

Molecular weight: 418.40

Ref: 3B-I1144

Isoliquiritin

CAS: 5041-81-6

Formula: C₂₁H₂₂O₉

Purity: 98%

Color and Shape: Solid

Molecular weight: 418.3940

Ref: IN-DA003R3X

Isoliquiritin

CAS: 5041-81-6

Isoliquiritin

Formula: C₂₁H₂₂O₉

Purity: ≥98%

Color and Shape: Solid

Molecular weight: 418.39

Ref: 54-BUP08910

Isoliquiritin

CAS: 5041-81-6

Insampaedoksan is a traditional herbal medicine used for antipyretic and antiinflammatory diseases, isoliquiritigenin is the main compound of it , thus , isoliquiritigenin has bioactivity effects such as antioxidant, estrogenic and anticancer.

Formula: C₂₁H₂₂O₉

Purity: 95%~99%

Color and Shape: Yellow powder

Molecular weight: 418.398

Ref: BP-BP0788

Isoliquiritin (Standard)

CAS: 5041-81-6

Isoliquiritin (Standard) is a reference standard for research and analysis in studies involving Isoliquiritin. 1. Isoliquiritin (Neoisoliquritin) has antitussive effects. 2. Isoliquiritin has antidepressant-like effects. 3. Isoliquiritin, liquiritin and isoliquirigenin inhibits the p53-dependent pathway and shows crosstalk between Akt activities.

Formula: C₂₁H₂₂O₉

Molecular weight: 418.394

Ref: TM-TMSM-3013

Isoliquiritin

CAS: 5041-81-6

Isoliquiritin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₂₁H₂₂O₉

Purity: (HPLC) ≥99%

Color and Shape: Powder

Molecular weight: 418.4

Ref: 11-1366S

Isoliquiritin

CAS: 5041-81-6

Isoliquiritin (Neoisoliquritin) has antitussive and antidepressant-like effects, and together with liquiritin and isoliquirigenin, it inhibits the p53-dependent pathway and exhibits crosstalk with Akt activities.

Formula: C₂₁H₂₂O₉

Purity: 98.65% - 99.88%

Color and Shape: Solid

Molecular weight: 418.394

Ref: TM-T5S0331

Isoliquiritin

CAS: 5041-81-6

Formula: C₂₁H₂₂O₉

Purity: ≥ 95.0%

Color and Shape: Light-yellow to dark yellow powder

Molecular weight: 418.40

Ref: 7W-GY1387

Isoliquiritin

CAS: 5041-81-6

Natural glycoside

Formula: C₂₁H₂₂O₉

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 418.4

Ref: 5G-80481

Isoliquiritin

CAS: 5041-81-6

Isoliquiritin is a bioactive compound, specifically a flavonoid, which is derived from the roots of Glycyrrhiza glabra, commonly known as licorice. It possesses diverse pharmacological properties with multiple modes of action, notably influencing pathways involved in oxidative stress and inflammation. Isoliquiritin acts as an antioxidant, scavenging free radicals and reducing oxidative damage at the cellular level. Additionally, it exhibits anti-inflammatory effects by modulating the expression of inflammatory cytokines and inhibiting specific signaling pathways like NF-κB.

Formula: C₂₁H₂₂O₉

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 418.39 g/mol

Ref: 3D-FN42767

Isoliquiritin

CAS: 5041-81-6

Formula: C₂₁H₂₂O₉

Molecular weight: 418.4

Ref: BE-RMT22109