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CAS 50629-82-8

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Halometasone

Description:
Halometasone is a synthetic corticosteroid primarily used for its anti-inflammatory and immunosuppressive properties in dermatological applications. It is characterized by its potent glucocorticoid activity, which makes it effective in treating various skin conditions such as eczema, psoriasis, and dermatitis. Halometasone exhibits a high affinity for glucocorticoid receptors, leading to a reduction in inflammation and immune response. The compound is typically formulated in topical preparations, allowing for localized treatment with minimal systemic absorption. Its chemical structure includes a steroid backbone, which is modified to enhance its therapeutic efficacy and reduce side effects. As with other corticosteroids, prolonged use can lead to skin atrophy and other local adverse effects, necessitating careful management of treatment duration. Halometasone is classified under the category of halogenated corticosteroids due to the presence of halogen atoms in its structure, which can influence its pharmacological properties. Overall, it is a valuable agent in dermatology, providing relief from inflammatory skin disorders.
Formula:C22H27ClF2O5
InChI:InChI=1S/C22H27ClF2O5/c1-10-4-11-12-5-15(24)13-6-16(27)14(23)7-19(13,2)21(12,25)17(28)8-20(11,3)22(10,30)18(29)9-26/h6-7,10-12,15,17,26,28,30H,4-5,8-9H2,1-3H3/t10-,11+,12+,15+,17+,19+,20+,21+,22+/m1/s1
InChI key:InChIKey=GGXMRPUKBWXVHE-MIHLVHIWSA-N
SMILES:F[C@@]12[C@]([C@]3([C@](C)(C[C@@H]1O)[C@](C(CO)=O)(O)[C@H](C)C3)[H])(C[C@H](F)C=4[C@]2(C)C=C(Cl)C(=O)C4)[H]
Synonyms:
  • (6Alpha,11Beta,14Xi,16Alpha)-2-Chloro-6,9-Difluoro-11,17,21-Trihydroxy-16-Methylpregna-1,4-Diene-3,20-Dione
  • (6Alpha,11Beta,16Alpha)-2-Chloro-6,9-Difluoro-11,17,21-Trihydroxy-16-Methylpregna-1,4-Diene-3,20-Dione
  • (6α,11β,16α)-2-Chloro-6,9-difluoro-11,17,21-trihydroxy-16-methylpregna-1,4-diene-3,20-dione
  • 2-Chloro-6α,9-difluoro-11β,17,21-trihydroxy-16α-methylpregna-1,4-diene-3,20-dione
  • Ba 48401
  • C 48401Ba
  • Halometasone
  • Halomethasone
  • Pregna-1,4-diene-3,20-dione, 2-chloro-6,9-difluoro-11,17,21-trihydroxy-16-methyl-, (6α,11β,16α)-
  • Sicorten
  • 2-Chloroflumethasone
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Found 10 products.