CAS 50847-11-5: Ibudilast

Description: Ibudilast, with the CAS number 50847-11-5, is a small organic molecule primarily recognized for its anti-inflammatory and neuroprotective properties. It is classified as a phosphodiesterase inhibitor, which means it can enhance the levels of cyclic nucleotides, such as cAMP and cGMP, within cells, leading to various physiological effects. Ibudilast is known to modulate the immune response and has been investigated for its potential therapeutic applications in conditions like multiple sclerosis, neuropathic pain, and asthma. The compound is typically administered orally and exhibits good bioavailability. Its mechanism of action involves not only the inhibition of phosphodiesterase but also the modulation of pro-inflammatory cytokines, making it a candidate for treating chronic inflammatory diseases. Additionally, Ibudilast has shown promise in preclinical studies for neurodegenerative disorders, highlighting its potential role in protecting neuronal cells from damage. Overall, its multifaceted effects on the immune system and nervous system make it a compound of interest in pharmacological research.

Formula: C₁₄H₁₈N₂O

InChI: InChI=1S/C14H18N2O/c1-9(2)13-12(14(17)10(3)4)11-7-5-6-8-16(11)15-13/h5-10H,1-4H3

InChI key: InChIKey=ZJVFLBOZORBYFE-UHFFFAOYSA-N

SMILES: O=C(C1=C2C=CC=CN2N=C1C(C)C)C(C)C

Synonyms:

• 1-(2-Isopropylpyrazolo[1,5-a]pyridin-3-yl)-2-methylpropan-1-one
• 1-Propanone, 2-methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]-
• 2-Isopropyl-3-isobutyrylpyrazolo[1,5-a]pyridine
• 2-Methyl-1-(2-propan-2-ylpyrazolo[1,5-a]pyridin-3-yl)propan-1-one
• 2-Methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]-1-propanone
• 2-Methyl-1-[2-(Propan-2-Yl)Pyrazolo[1,5-A]Pyridin-3-Yl]Propan-1-One
• 3-Isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine
• Av 411
• Kc 404
• Ketas
• Pinatos
• Pyrazolo[1,5-a]pyridine, 1-propanone deriv.

Ibudilast

CAS: 50847-11-5

• Formula: C₁₄H₁₈N₂O
• Purity: >98.0%(T)(HPLC)
• Color and Shape: White to Almost white powder to crystal
• Molecular weight: 230.31

1-Propanone, 2-methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]-

CAS: 50847-11-5

• Formula: C₁₄H₁₈N₂O
• Purity: 99%
• Color and Shape: Solid
• Molecular weight: 230.3055

Ibudilast

CAS: 50847-11-5

• Formula: C₁₄H₁₈N₂O
• Color and Shape: White To Off-White Solid
• Molecular weight: 230.31

Ibudilast-d7

CAS: 50847-11-5

• Formula: C₁₄H₁₁D₇N₂O
• Color and Shape: White To Off-White Solid
• Molecular weight: 237.35

Ibudilast

CAS: 50847-11-5

• Purity: 99.9%
• Molecular weight: 230.31g/mol

3-Isobutyryl-2-Isopropylpyrazolo[1,5-a]Pyridine

CAS: 50847-11-5

• Purity: 99%
• Molecular weight: 230.31g/mol

Ibudilast

CAS: 50847-11-5

Ibudilast (MN-166)(KC-404;AV-411;MN-166) is a relatively nonselective phosphodiesterase inhibitor. It is approved for use as an …

• Formula: C₁₄H₁₈N₂O
• Purity: 99.34% - 99.94%
• Color and Shape: White Solid
• Molecular weight: 230.31

Ibudilast

CAS: 50847-11-5

• Formula: C₁₄H₁₈N₂O
• Purity: ≥ 99.0%
• Color and Shape: White powder
• Molecular weight: 230.31

Ibudilast-d7

CAS: 50847-11-5

Applications Ibudilast-d7 is the labeled analogue of Ibudilast (I125000), a leukotriene D4 antagonist. Used as …

• Formula: C₁₄H₁₁D₇N₂O
• Color and Shape: Neat
• Molecular weight: 237.35

1-(2-Isopropylpyrazolo[1,5-a]pyridin-3-yl)-2-methylpropan-1-one

CAS: 50847-11-5

• Purity: 97.0%
• Color and Shape: Solid, White to very pale yellow powder
• Molecular weight: 230.31100463867188

Ibudilast

CAS: 50847-11-5

Phosphodiesterase PDE4 inhibitor

• Formula: C₁₄H₁₈N₂O
• Purity: Min. 95%
• Color and Shape: Off-White Powder
• Molecular weight: 230.14191

Ibudilast

CAS: 50847-11-5

Applications A leukotriene D4 antagonist. Used as an antiallergic, antiasthmatic, and vasodilator (cerebral). PDE inhibitor …

• Formula: C₁₄H₁₈N₂O
• Color and Shape: Neat
• Molecular weight: 230.31