CAS 50847-11-5
:Ibudilast
Description:
Ibudilast, with the CAS number 50847-11-5, is a small organic molecule primarily recognized for its anti-inflammatory and neuroprotective properties. It is classified as a phosphodiesterase inhibitor, which means it can enhance the levels of cyclic nucleotides, such as cAMP and cGMP, within cells, leading to various physiological effects. Ibudilast is known to modulate the immune response and has been investigated for its potential therapeutic applications in conditions like multiple sclerosis, neuropathic pain, and asthma. The compound is typically administered orally and exhibits good bioavailability. Its mechanism of action involves not only the inhibition of phosphodiesterase but also the modulation of pro-inflammatory cytokines, making it a candidate for treating chronic inflammatory diseases. Additionally, Ibudilast has shown promise in preclinical studies for neurodegenerative disorders, highlighting its potential role in protecting neuronal cells from damage. Overall, its multifaceted effects on the immune system and nervous system make it a compound of interest in pharmacological research.
Formula:C14H18N2O
InChI:InChI=1S/C14H18N2O/c1-9(2)13-12(14(17)10(3)4)11-7-5-6-8-16(11)15-13/h5-10H,1-4H3
InChI key:InChIKey=ZJVFLBOZORBYFE-UHFFFAOYSA-N
SMILES:C(C(C)C)(=O)C1=C2N(N=C1C(C)C)C=CC=C2
Synonyms:- 1-(2-Isopropylpyrazolo[1,5-a]pyridin-3-yl)-2-methylpropan-1-one
- 1-Propanone, 2-methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]-
- 2-Isopropyl-3-isobutyrylpyrazolo[1,5-a]pyridine
- 2-Methyl-1-(2-propan-2-ylpyrazolo[1,5-a]pyridin-3-yl)propan-1-one
- 2-Methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]-1-propanone
- 2-Methyl-1-[2-(Propan-2-Yl)Pyrazolo[1,5-A]Pyridin-3-Yl]Propan-1-One
- 3-Isobutyryl-2-isopropylpyrazolo[1,5-a]pyridine
- Av 411
- Kc 404
- Ketas
- Pinatos
- See more synonyms
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Found 14 products.
Ibudilast
CAS:Formula:C14H18N2OPurity:>98.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:230.311-Propanone, 2-methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]-
CAS:Formula:C14H18N2OPurity:99%Color and Shape:SolidMolecular weight:230.30553-Isobutyryl-2-Isopropylpyrazolo[1,5-a]Pyridine
CAS:3-Isobutyryl-2-Isopropylpyrazolo[1,5-a]PyridineFormula:C14H18N2OPurity:99%Color and Shape:SolidMolecular weight:230.31Ibudilast
CAS:1-(2-Isopropylpyrazolo[1,5-a]pyridin-3-yl)-2-methylpropan-1-oneFormula:C14H18N2OPurity:99%Molecular weight:230.31Ibudilast
CAS:1-(2-Isopropylpyrazolo[1,5-a]pyridin-3-yl)-2-methylpropan-1-oneFormula:C14H18N2OPurity:98%Molecular weight:230.31Ibudilast
CAS:Ibudilast (MN-166)(KC-404;AV-411;MN-166) is a relatively nonselective phosphodiesterase inhibitor. It is approved for use as an anti-inflammatory in Japan.Formula:C14H18N2OPurity:99.83% - >99.99%Color and Shape:White SolidMolecular weight:230.31Ibudilast
CAS:Phosphodiesterase PDE4 inhibitorFormula:C14H18N2OPurity:Min. 95%Color and Shape:Off-White PowderMolecular weight:230.141911-(2-Isopropylpyrazolo[1,5-a]pyridin-3-yl)-2-methylpropan-1-one
CAS:Formula:C14H18N2OPurity:99%Color and Shape:Solid, White to very pale yellow powderMolecular weight:230.311Ibudilast-d7
CAS:Controlled ProductApplications Ibudilast-d7 is the labeled analogue of Ibudilast (I125000), a leukotriene D4 antagonist. Used as an antiallergic, antiasthmatic, and vasodilator (cerebral).
References Nishino, K., et al.: Japan J. Pharmacol., 33, 267 (1983); Ohashi, M., et al.: Arch. Int. Pharmacodyn., 280, 216 (1986); Armstead, W.M., et al.: J. Pharmacol., Exp. Ther., 244, 138 (1988)Formula:C14H11D7N2OColor and Shape:NeatMolecular weight:237.35Ibudilast
CAS:Controlled ProductApplications A leukotriene D4 antagonist. Used as an antiallergic, antiasthmatic, and vasodilator (cerebral). PDE inhibitor (non-selective).
References Nishino, K., et al.: Japan J. Pharmacol., 33, 267 (1983), Ohashi, M., et al.: Arch. Int. Pharmacodyn., 280, 216 (1986), Armstead, W.M., et al.: J. Pharmacol., Exp. Ther., 244, 138 (1988),Formula:C14H18N2OColor and Shape:NeatMolecular weight:230.31
![1-Propanone, 2-methyl-1-[2-(1-methylethyl)pyrazolo[1,5-a]pyridin-3-yl]-](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA00I944.jpg&w=3840&q=75)
![1-(2-Isopropylpyrazolo[1,5-a]pyridin-3-yl)-2-methylpropan-1-one](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb%2FF069148.jpg&w=3840&q=75)
