CAS 509-20-6: Aconine
Description:Aconine, with the CAS number 509-20-6, is an alkaloid derived from the plant Aconitum, commonly known as monkshood or wolfsbane. It is characterized by its potent pharmacological properties, particularly its neurotoxic effects. Aconine is known to interact with voltage-gated sodium channels, leading to disruptions in nerve signal transmission, which can result in symptoms such as muscle paralysis and cardiovascular disturbances. The compound is typically found in the roots and leaves of Aconitum species, and its structure features a complex bicyclic framework typical of many alkaloids. Due to its toxicity, aconine has limited therapeutic applications and is primarily of interest in toxicology and pharmacology research. Handling aconine requires caution, as it can be lethal in relatively small doses. Its presence in herbal remedies and traditional medicine underscores the importance of understanding its effects and potential risks. Overall, aconine exemplifies the dual nature of many natural compounds, possessing both significant biological activity and potential hazards.
Formula:C25H41NO9
InChI:InChI=1S/C25H41NO9/c1-6-26-9-22(10-32-2)12(27)7-13(33-3)24-11-8-23(30)19(28)14(11)25(31,20(29)21(23)35-5)15(18(24)26)16(34-4)17(22)24/h11-21,27-31H,6-10H2,1-5H3/t11-,12-,13+,14-,15+,16+,17-,18-,19-,20+,21+,22+,23-,24+,25-/m1/s1
InChI key:InChIKey=SQMGCPHFHQGPIF-UUKFDUHUSA-N
SMILES:OC1CC(OC)C23C4N(CC)CC1(COC)C3C(OC)C4C5(O)C(O)C(OC)C6(O)CC2C5C6O
- Synonyms:
- (1a,3a,6a,14a,15a,16b)-20-Ethyl-1,6,16-trimethoxy-4-(methoxymethyl)aconitane-3,8,13,14,15-pentol
- (1alpha,3alpha,6alpha,14alpha,15alpha,16beta)-20-Ethyl-1,6,16-trimethoxy-4-(methoxymethyl)aconitane-3,8,13,14,15-pentol
- 11aH-12,3,6a-Ethanylylidene-7,9-methanonaphth[2,3-b]azocine, aconitane-3,8,13,14,15-pentol deriv.
- Aconine
- Aconitane-3,8,13,14,15-pentol, 20-ethyl-1,6,16-trimethoxy-4-(methoxymethyl)-, (1α,3α,6α,14α,15α,16β)-
- Aconitysat
- Jesaconine
- See more synonyms
