CAS 509074-26-4

Benzenesulfonyl chloride, 4-(5-methyl-3-phenyl-4-isoxazolyl)-

Description:

Benzenesulfonyl chloride, 4-(5-methyl-3-phenyl-4-isoxazolyl)-, is a chemical compound characterized by its sulfonyl chloride functional group attached to a substituted isoxazole ring. This compound typically exhibits a white to light yellow crystalline appearance and is known for its reactivity due to the presence of the sulfonyl chloride moiety, which can readily participate in nucleophilic substitution reactions. The isoxazole ring contributes to its unique chemical properties, including potential biological activity and applications in medicinal chemistry. It is soluble in organic solvents such as dichloromethane and chloroform but is generally insoluble in water. Safety precautions are necessary when handling this compound, as it can be corrosive and may cause irritation to the skin, eyes, and respiratory system. Its applications may include use as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds, highlighting its significance in chemical research and development.

Formula: C₁₆H₁₂ClNO₃S

Synonyms:

• 4-(5-Methyl-3-Phenyl-4-Isoxazolyl)Benzenesulfonyl Chloride
• Parecoxib Sodium Intermediate-1
• 4-(5-Methyl-3-Phenylisoxazol-4-Yl)Benzene-1-Sulfonyl Chloride

Valdecoxib Impurity F

CAS: 509074-26-4

Formula: C₁₆H₁₂ClNO₃S

Purity: 97%

Color and Shape: Solid

Molecular weight: 333.7894

Ref: IN-DA00DE75

4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonyl chloride

CAS: 509074-26-4

4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonyl chloride

Purity: 98%

Molecular weight: 333.79g/mol

Ref: 54-OR1011152

Valdecoxib Impurity 35

CAS: 509074-26-4

Formula: C₁₆H₁₂ClNO₃S

Color and Shape: Off-White Solid

Molecular weight: 333.79

Ref: 4Z-V-097

4-(5-Methyl-3-phenylisoxazol-4-yl)benzenesulfonyl Chloride (Valdecoxib Sulfonyl Chloride)

Controlled Product

CAS: 509074-26-4

Formula: C₁₆H₁₂ClNO₃S

Color and Shape: Neat

Molecular weight: 333.79

Ref: 86-MM0937.03

4-(5-Methyl-3-phenylisoxazol-4-yl)benzene-1-sulfonyl chloride

CAS: 509074-26-4

Purity: 95.0%

Molecular weight: 333.7900085449219

Ref: 10-F463082

Valdecoxib Sulfonyl Chloride

Controlled Product

CAS: 509074-26-4

Stability Hygroscopic
Applications Valdecoxib Sulfonyl Chloride is an impurity in the preparation of the cyclooxygenase-2 inhibitor, Valdecoxib (V090000) and its metabolites.
References Erdelyi, P. et al.: Bioorg. Med. Chem., 16, 5322 (2008);

Formula: C₁₆H₁₂ClNO₃S

Color and Shape: Neat

Molecular weight: 333.79

Ref: TR-V090015

Valdecoxib Sulfonyl Chloride

CAS: 509074-26-4

Formula: C₁₆H₁₂ClNO₃S

Molecular weight: 333.79

Ref: ST-EA-CP-V38002