CAS 509074-26-4
:Benzenesulfonyl chloride, 4-(5-methyl-3-phenyl-4-isoxazolyl)-
Description:
Benzenesulfonyl chloride, 4-(5-methyl-3-phenyl-4-isoxazolyl)-, is a chemical compound characterized by its sulfonyl chloride functional group attached to a substituted isoxazole ring. This compound typically exhibits a white to light yellow crystalline appearance and is known for its reactivity due to the presence of the sulfonyl chloride moiety, which can readily participate in nucleophilic substitution reactions. The isoxazole ring contributes to its unique chemical properties, including potential biological activity and applications in medicinal chemistry. It is soluble in organic solvents such as dichloromethane and chloroform but is generally insoluble in water. Safety precautions are necessary when handling this compound, as it can be corrosive and may cause irritation to the skin, eyes, and respiratory system. Its applications may include use as an intermediate in the synthesis of pharmaceuticals, agrochemicals, and other organic compounds, highlighting its significance in chemical research and development.
Formula:C16H12ClNO3S
Synonyms:- 4-(5-Methyl-3-Phenyl-4-Isoxazolyl)Benzenesulfonyl Chloride
- Parecoxib Sodium Intermediate-1
- 4-(5-Methyl-3-Phenylisoxazol-4-Yl)Benzene-1-Sulfonyl Chloride
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Found 8 products.
4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonyl chloride
CAS:4-(5-Methyl-3-phenyl-4-isoxazolyl)benzenesulfonyl chlorideFormula:C16H12ClNO3SPurity:>98%Molecular weight:333.79Valdecoxib Impurity F
CAS:Formula:C16H12ClNO3SPurity:97%Color and Shape:SolidMolecular weight:333.7894Valdecoxib Impurity 35
CAS:Formula:C16H12ClNO3SColor and Shape:Off-White SolidMolecular weight:333.794-(5-Methyl-3-phenylisoxazol-4-yl)benzene-1-sulfonyl chloride
CAS:Purity:95.0%Molecular weight:333.79000854492194-(5-Methyl-3-phenylisoxazol-4-yl)benzenesulfonyl Chloride (Valdecoxib Sulfonyl Chloride)
CAS:Controlled ProductFormula:C16H12ClNO3SColor and Shape:NeatMolecular weight:333.79Valdecoxib Sulfonyl Chloride
CAS:4-(5-Methyl-3-phenylisoxazol-4-yl)benzene-1-sulfonyl chlorideFormula:C16H12ClNO3SPurity:97%Molecular weight:333.79Valdecoxib Sulfonyl Chloride
CAS:Controlled ProductStability Hygroscopic
Applications Valdecoxib Sulfonyl Chloride is an impurity in the preparation of the cyclooxygenase-2 inhibitor, Valdecoxib (V090000) and its metabolites.
References Erdelyi, P. et al.: Bioorg. Med. Chem., 16, 5322 (2008);Formula:C16H12ClNO3SColor and Shape:NeatMolecular weight:333.79







