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CAS 51-15-0

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Pralidoxime chloride

Description:
Pralidoxime chloride, with the CAS number 51-15-0, is a chemical compound primarily used as an antidote for organophosphate poisoning, particularly in cases of nerve agent exposure. It functions by reactivating acetylcholinesterase, an enzyme inhibited by organophosphates, thus restoring normal neurotransmission. The compound is a quaternary ammonium salt, which contributes to its solubility in water and limits its ability to cross the blood-brain barrier. Pralidoxime chloride is typically administered via injection and is often used in conjunction with atropine to counteract the effects of cholinergic toxicity. Its chemical structure includes a pyridine ring and a hydroxyl group, which are essential for its reactivation mechanism. The substance is generally considered to have a low toxicity profile when used appropriately, but it can cause side effects such as muscle weakness or respiratory issues if misused. Proper storage and handling are crucial, as it should be kept in a cool, dry place away from incompatible substances.
Formula:C7H9N2O·Cl
InChI:InChI=1S/C7H8N2O.ClH/c1-9-5-3-2-4-7(9)6-8-10;/h2-6H,1H3;1H
InChI key:InChIKey=HIGSLXSBYYMVKI-UHFFFAOYSA-N
SMILES:C(=NO)C=1[N+](C)=CC=CC1.[Cl-]
Synonyms:
  • (E)-(1-methylpyridin-2(1H)-ylidene)-N-oxomethanaminium chloride
  • 1-Methyl-2-aldoximinopyridinium chloride
  • 1-Methylpyridinium-2-aldoxime chloride
  • 2-Formyl-1-methylpyridinium chloride oxime
  • 2-Hydroxyiminomethyl-1-Methylpyridinium Chloride
  • 2-PAM chloride
  • 2-Pralidoxime chloride
  • 2-[(E)-(hydroxyimino)methyl]-1-methylpyridinium chloride
  • 2-[(Hydroxyimino)methyl]-1-methylpyridin-1-ium chloride
  • N-Methylpyridinium-2-aldoxime chloride
  • See more synonyms
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