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CAS 51-56-9

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Homatropine hydrobromide

Description:
Homatropine hydrobromide is a synthetic anticholinergic agent primarily used in ophthalmology as a mydriatic and cycloplegic agent. It is a quaternary ammonium compound derived from tropic acid and is structurally related to atropine. The substance appears as a white to off-white crystalline powder, which is soluble in water and alcohol. Its mechanism of action involves blocking the action of acetylcholine at muscarinic receptors, leading to pupil dilation and paralysis of the ciliary muscle, which is useful for diagnostic procedures in the eye. Homatropine hydrobromide is typically administered as eye drops, and its effects can last for several hours. While generally well-tolerated, potential side effects may include increased intraocular pressure, dry mouth, and blurred vision. Due to its anticholinergic properties, caution is advised in patients with certain medical conditions, such as glaucoma or urinary retention. Overall, homatropine hydrobromide is an important tool in clinical practice for facilitating eye examinations.
Formula:C16H21NO3·BrH
InChI:InChI=1/C16H21NO3.BrH/c1-17-12-7-8-13(17)10-14(9-12)20-16(19)15(18)11-5-3-2-4-6-11;/h2-6,12-15,18H,7-10H2,1H3;1H/t12-,13+,14+,15?;
InChI key:InChIKey=DWSGTFTVBLXELC-RDYJJYPNNA-N
SMILES:O(C(C(O)C1=CC=CC=C1)=O)[C@H]2C[C@@]3(N(C)[C@](C2)(CC3)[H])[H].Br
Synonyms:
  • (1R,5S)-3-{[(2R)-2-hydroxy-2-phenylacetyl]oxy}-8-methyl-8-azoniabicyclo[3.2.1]octane
  • (±)-Homatropine bromide
  • 1α<span class="text-smallcaps">H</smallcap>,5α<smallcap>H</span>-Tropan-3α-ol, mandelate (ester), hydrobromide
  • 8-Methyl-8-Azabicyclo[3.2.1]Oct-3-Yl Hydroxy(Phenyl)Acetate
  • 8-Methyl-8-Azabicyclo[3.2.1]Oct-3-Yl Hydroxy(Phenyl)Acetate Hydrobromide (1:1)
  • Benzeneacetic acid, α-hydroxy-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide
  • Benzeneacetic acid, α-hydroxy-, (3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide (1:1)
  • Benzeneacetic acid, α-hydroxy-, 8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide, endo-
  • Homatropine HBr
  • Homatropine Hydrobromide
  • See more synonyms
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Found 16 products.
  • Homatropine Hydrobromide

    CAS:
    Formula:C16H21NO3·HBr
    Purity:>99.0%(T)
    Color and Shape:White to Almost white powder to crystal
    Molecular weight:356.26

    Ref: 3B-H0155

    1g
    58.00€
  • HOMATROPINE HYDROBROMIDE CRS

    CAS:
    HOMATROPINE HYDROBROMIDE CRS
    Formula:C16H22BrNO3
    Color and Shape:Powder

    Ref: 41-H0800000

    100mg
    115.00€
  • Homatropine hydrobromide

    CAS:
    Homatropine hydrobromide
    Formula:C16H21NO3
    Purity:99.7%
    Color and Shape:Off-White
    Molecular weight:275.15214

    Ref: 47-185

    100mg
    242.00€
  • Homatropine Hydrobromide

    CAS:
    Vegetable alkaloids, natural or reproduced by synthesis, their salts and other derivatives, nesoi
    Formula:C16H21NO3·HBr
    Color and Shape:White Powder
    Molecular weight:355.07831
  • Benzeneacetic acid, a-hydroxy-,(3-endo)-8-methyl-8-azabicyclo[3.2.1]oct-3-yl ester, hydrobromide

    CAS:
    Formula:C16H22BrNO3
    Purity:98%
    Color and Shape:Solid
    Molecular weight:356.2548

    Ref: IN-DA00I94X

    1g
    97.00€
    5g
    161.00€
    10g
    277.00€
  • Homatropine hydrobromide, USP grade

    CAS:
    Formula:C16H21NO3·HBr
    Purity:≤ 0.1%
    Color and Shape:White to off-white crystalline powder
    Molecular weight:356.25

    Ref: 7W-GX2904

    ne
    To inquire
  • Homatropine hydrobromide

    CAS:
    Formula:C16H21NO3·HBr
    Purity:(Titration) 99.0 - 101.0 %
    Color and Shape:White, off-white or pale yellow powder
    Molecular weight:356.25

    Ref: 7W-GE3427

    1g
    33.00€
    10g
    122.00€
    25g
    213.00€
  • Homatropine HBr

    CAS:
    Formula:C16H21NO3·HBr
    Color and Shape:White To Off-White Solid
    Molecular weight:275.35 80.91

    Ref: 4Z-H-181

    5mg
    To inquire
    10mg
    349.00€
    25mg
    444.00€
    50mg
    635.00€
    100mg
    To inquire
  • Homatropine Hydrobromide

    Controlled Product
    CAS:
    Formula:C16H21NO3·BrH
    Color and Shape:Neat
    Molecular weight:356.25

    Ref: 86-MM1649.00

    100mg
    To inquire
  • Homatropine Bromide

    CAS:
    Molecular weight:356.26

    Ref: 10-F987619

    1g
    94.00€
    5g
    156.00€
    500mg
    79.00€
  • Homatropine hydrobromide

    Controlled Product
    CAS:
    Formula:C16H21NO3·BrH
    Color and Shape:Neat
    Molecular weight:356.25

    Ref: 04-C14213375

    50mg
    To inquire
  • Homatropine hydrobromide

    CAS:
    Natural alkaloid
    Formula:C16H21NO3HBr
    Purity:≥ 95.0 % (HPLC)
    Color and Shape:Powder
    Molecular weight:356.25

    Ref: 5G-84120

    50mg
    185.00€
    250mg
    678.00€
    500mg
    1,233.00€
    1000mg
    2,312.00€
  • rac Homatropine Hydrobromide

    Controlled Product
    CAS:
    <p>Applications Homatropine is an anticholinergic agent. Homatropine acts as an inhibitor of the muscarinic acetylcholine receptors. Homatropine is used in eye drops as a cycloplegic and as a mydriatic, to dilate the pupil.<br>References Mattila, M.J. et al.: Ann. Med. Exp. Biol. Fen., 45, 412 (1967); Gambill, H. et al.: Arch. Ophthamol., 77, 740 (1967); Sund, R.B.: Med. Norsk Farmac. Sels., 33, 143 (1971);<br></p>
    Formula:C16H21NO3·BrH
    Color and Shape:White To Off-White
    Molecular weight:356.25

    Ref: TR-H459200

    50mg
    105.00€
    500mg
    172.00€
    2500mg
    427.00€
  • Homatropine hydrobromide

    CAS:
    <p>Anticholinergic drug; antagonist at muscarinic acetylcholine receptors</p>
    Formula:C16H21NO3·HBr
    Purity:Min. 95%
    Color and Shape:White Powder
    Molecular weight:356.26 g/mol

    Ref: 3D-FH09765

    5g
    254.00€
    10g
    382.00€
    25g
    724.00€
    50g
    1,137.00€
    100g
    1,820.00€
  • rac Homatropine Hydrobromide-d3

    Controlled Product
    CAS:
    Formula:C16D3H18NO3·HBr
    Color and Shape:Neat
    Molecular weight:359.273

    Ref: TR-H459202

    100mg
    3,428.00€
  • Homatropine Hydrobromide

    CAS:
    Color and Shape:Neat

    Ref: 61-FOR1649.00

    10mg
    Discontinued
    Discontinued product