CAS 51018-28-1

Methylpseudoephedrine

Description:

Methylpseudoephedrine, with the CAS number 51018-28-1, is a chemical compound that belongs to the class of sympathomimetic amines. It is structurally related to pseudoephedrine, a common decongestant. Methylpseudoephedrine is characterized by its ability to act as a nasal decongestant, primarily by constricting blood vessels in the nasal passages, thereby reducing swelling and congestion. The compound is typically found in formulations aimed at alleviating symptoms of respiratory conditions, such as colds and allergies. It exhibits a chiral center, which contributes to its pharmacological activity. Methylpseudoephedrine is generally administered orally and is known for its stimulant effects, which can lead to increased heart rate and blood pressure. Due to its potential for misuse, particularly in the synthesis of illicit substances, its regulation is often stringent in various jurisdictions. Safety and efficacy profiles are essential considerations in its use, and it may have side effects similar to other sympathomimetics, including insomnia, nervousness, and dizziness.

Formula: C₁₁H₁₇NO

InChI: InChI=1/C11H17NO/c1-9(12(2)3)11(13)10-7-5-4-6-8-10/h4-9,11,13H,1-3H3/t9-,11+/m0/s1

InChI key: InChIKey=FMCGSUUBYTWNDP-GXSJLCMTSA-N

SMILES: [C@H]([C@@H](N(C)C)C)(O)C1=CC=CC=C1

Synonyms:

• (+)-N-Methyl-ψ-ephedrine
• (+)-N-Methylpseudoephedrine
• (1S,2S)-2-(dimethylamino)-1-phenylpropan-1-ol
• (1S,2S)-N-Methylephedrine
• (αS)-α-[(1S)-1-(Dimethylamino)ethyl]benzenemethanol
• Benzenemethanol, α-[(1S)-1-(dimethylamino)ethyl]-, (αS)-
• Benzenemethanol, α-[1-(dimethylamino)ethyl]-, [S-(R*,R*)]-
• Methylpseudoephedrine
• d-(1S,2S)-Methylpseudoephedrine
• (1S,2S)-(+)-N-Methylpseudoephedrine
• (1S,2S)-(+)-N-METHYL-PSI-EPHEDRINE
• (1S,2S)-DimEtamino-phenyl-propane-1-ol
• (1S,2S)-2-(Dimethylamino)-1-phenyl-propan-1-ol
• (+)-N-Methylpseudoephedrine, (1S,2S)-2-Dimethylamino-1-phenylpropanol
• (1S,2S)-Dimethylamino-phenyl-propane-1-ol, GC 95%
• METHYLPSEUDOEPHEDRINE, (+)-1S,2S-N-
• (S)-α-[(S)-1-(Dimethylamino)ethyl]benzenemethanol
• (+)-1S,2S-METHYLPSEUDOEPHEDRINE

N-Methyl Pseudoephedrine

CAS: 51018-28-1

Formula: C₁₁H₁₇NO

Molecular weight: 179.26

Ref: 4Z-P-247013

N-Methyl Pseudoephedrine

Controlled Product

CAS: 51018-28-1

Applications N-Methylpseudoephedrine is a N-methylated analogue of the non-selective adrenergic agonist Pseudoephedrine (P839350). N-Methylpseudoephedrine is an alkaloid from Ephedra species widely used in Chinese medicine.
References Kim, H.K. et al.: Chem. Pharmac. Bull., 51, 1382 (2003); Krizevski, R. et al.: Phytochemistry, 71, 895 (2010); Cui, J. et al.: Phytochem. Anal., 2, 116 (1991);

Formula: C₁₁H₁₇NO

Color and Shape: Neat

Molecular weight: 179.26

Ref: TR-M326455

(1S,2S)-(+)-N-Methylpseudoephedrine

Controlled Product

CAS: 51018-28-1

(1S,2S)-(+)-N-Methylpseudoephedrine is an alkaloid that is a structural analog of ephedrine and methylephedrine. It has been used in the treatment of coughs, colds, headache, and hay fever. The pharmacokinetic properties of (1S,2S)-(+)-N-Methylpseudoephedrine have been studied in humans. The half-life of this drug is around 2 hours and its bioavailability is about 80%. This drug has also been used as a matrix effect for chromatographic analysis. (1S,2S)-(+)-N-Methylpseudoephedrine can interact with other drugs such as monoamine oxidase inhibitors and tricyclic antidepressants to cause hypertensive crisis. Analysis methods include titration calorimetry and analytical method.

Formula: C₁₁H₁₇NO

Purity: Min. 95 Area-%

Color and Shape: Powder

Molecular weight: 179.26 g/mol

Ref: 3D-FM175545