CAS 51166-71-3

Di-O-methyl-β-cyclodextrin

Description:

Di-O-methyl-β-cyclodextrin is a modified derivative of β-cyclodextrin, which is a cyclic oligosaccharide composed of seven glucose units. This compound features two methoxy groups attached to the hydroxyl positions of the glucose units, enhancing its solubility in organic solvents and improving its ability to form inclusion complexes with various guest molecules. Di-O-methyl-β-cyclodextrin exhibits characteristics such as increased lipophilicity compared to native β-cyclodextrin, making it useful in pharmaceutical applications for drug delivery and stabilization. It has a relatively low toxicity profile and is generally recognized as safe for use in food and pharmaceutical formulations. The compound's ability to encapsulate hydrophobic compounds allows for improved bioavailability and controlled release of active ingredients. Additionally, it can enhance the stability of sensitive compounds against degradation. Its applications extend to areas such as cosmetics, food science, and environmental remediation, where it can aid in the solubilization and delivery of various substances.

Formula: C₅₆H₉₈O₃₅

InChI: InChI=1S/C56H98O35/c1-64-15-22-36-29(57)43(71-8)50(78-22)86-37-23(16-65-2)80-52(45(73-10)30(37)58)88-39-25(18-67-4)82-54(47(75-12)32(39)60)90-41-27(20-69-6)84-56(49(77-14)34(41)62)91-42-28(21-70-7)83-55(48(76-13)35(42)63)89-40-26(19-68-5)81-53(46(74-11)33(40)61)87-38-24(17-66-3)79-51(85-36)44(72-9)31(38)59/h22-63H,15-21H2,1-14H3/t22-,23-,24-,25-,26-,27-,28-,29+,30+,31+,32+,33+,34+,35+,36-,37-,38-,39-,40-,41-,42-,43-,44-,45-,46-,47-,48-,49-,50-,51-,52-,53-,54-,55-,56-/m1/s1

InChI key: InChIKey=QGKBSGBYSPTPKJ-UZMKXNTCSA-N

SMILES: C(OC)[C@@H]1[C@@]2([C@H](O)[C@@H](OC)[C@](O1)(O[C@@]3([C@@H](COC)O[C@@]([C@H](OC)[C@H]3O)(O[C@@]4([C@@H](COC)O[C@@]([C@H](OC)[C@H]4O)(O[C@@]5([C@@H](COC)O[C@](O[C@]6([C@H](O)[C@@H](OC)[C@@](O[C@]7([C@H](O)[C@@H](OC)[C@@](O[C@]8([C@H](O)[C@@H](OC)[C@@](O2)(O[C@@H]8COC)[H])[H])(O[C@@H]7COC)[H])[H])(O[C@@H]6COC)[H])[H])([C@H](OC)[C@H]5O)[H])[H])[H])[H])[H])[H])[H])[H]

Synonyms:

• 2,4,7,9,12,14,17,19,22,24,27,29,32,34-Tetradecaoxaoctacyclo[31.2.2.2^3,6.2^8,11.2^13,16.2^18,21.2^23,26.2^28,31]nonatetracontane, β-cyclodextrin deriv.
• 2,6-2-Methyl-Beta-Cyclodextrin
• 2,6-Di-O-Methyl-Beta-Cyclodextrin
• 2,6-Di-O-methyl-β-cyclodextrin
• 2,6-Dimethyl-β-cyclodextrin
• 2^A,2^B,2^C,2^D,2^E,2^F,2^G,6^A,6^B,6^C,6^D,6^E,6^F,6^G-Tetradeca-O-methyl-β-cyclodextrin
• 2^A,6^A-Di-O-methyl-β-cyclodextrin
• Beta W 7M1.8
• Di-O-methyl-β-cyclodextrin
• Dimeb
• Dimeb 50
• Dimethyl-β-cyclodextrin
• Hepta-(2,6-di-oxy-methyl)-β-cyclodextrin
• Heptakis(2,6-di-O-methyl)-β-cyclodextrin
• Tetradeca-O-methyl-β-cyclodextrin
• Tetradecakis-2,6-O-methylcycloheptaamylose
• β-Cyclodextrin, 2^A,2^B,2^C,2^D,2^E,2^F,2^G,6^A,6^B,6^C,6^D,6^E,6^F,6^G-tetradeca-O-methyl-
• β-Cyclodextrin, 2A,2B,2C,2D,2E,2F,2G,6A,6B,6C,6D,6E,6F,6G-tetradeca-O-methyl-
• 2A,2B,2C,2D,2E,2F,2G,6A,6B,6C,6D,6E,6F,6G-Tetradeca-O-methyl-β-cyclodextrin

2,6-Di-O-methyl-β-cyclodextrin

CAS: 51166-71-3

Formula: C₅₆H₉₈O₃₅

Purity: 98%

Color and Shape: Solid

Molecular weight: 1331.3563

Ref: IN-DA00I95Q

Heptakis(2,6-di-O-methyl)-β-cyclodextrin content > 35% (DS~14)

CAS: 51166-71-3

Heptakis(2,6-di-O-methyl)-β-cyclodextrin content > 35% (DS~14)

Formula: C₅₆H₉₈O₃₅

Purity: 95%

Color and Shape: Solid-Powder

Molecular weight: 1331.35631

Ref: 54-BICY1000

Heptakis(2,6-di-O-methyl)-b-cyclodextrin

CAS: 51166-71-3

Formula: C₅₆H₉₈O₃₅

Purity: ≥ 98% (2,6-Di-O-methyl-b-CD + other methyl CDs)

Color and Shape: White to off-white powder

Molecular weight: 1331.36

Ref: 7W-GC9584

Di-O-methyl-b-cyclodextrin (90%)

Controlled Product

CAS: 51166-71-3

Applications Induces the release of cholesterol from cholesterol-rich lipid rafts located on the surface of cells, making it a good agent for removing cholesterol from processed foods
References Krajian, H., et al.: Anal. Bioanal. Chem., 394, 2193 (2009), Perez-Cruz, F., et al.: Bioorg. Med. Chem., 17, 4604 (2009), Motoyama, K., et al.: Biol. Pharm. Bull., 32, 700 (2009), Padula, C., et al.: Int. J. Pharm., 372, 12 (2009), Chen, Z., et al.: J. Pharm. Sci., 98, 229 (2009),

Formula: C₅₆H₉₈O₃₅

Purity: 90%

Color and Shape: Neat

Molecular weight: 1331.36

Ref: TR-D470870

2,6-Dimethyl-b-cyclodextrin - Technical

CAS: 51166-71-3

This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.

Formula: C₅₆H₉₈O₃₅

Purity: Min. 98%

Color and Shape: White Powder

Molecular weight: 1,331.36 g/mol

Ref: 3D-OD08100

2,6-Dimethyl-β-cyclodextrin

CAS: 51166-71-3

This functionalised beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.

Formula: C₅₆H₉₈O₃₅

Purity: Min. 98 Area-%

Molecular weight: 1,331.36 g/mol

Ref: 3D-W-202928

2,6-Dimethyl-beta-cyclodextrin

CAS: 51166-71-3

This beta-cyclodextrin (β-CD) derivative is a functionalized cyclic oligosaccharide composed of seven glucose units, characterized by a hydrophilic exterior and a lipophilic cavity (bigger than α-CD and smaller than γ-CDs), which allows it to encapsulate various guest molecules. This structural feature facilitates its use in multiple applications, including pharmaceuticals, food enhancement, and cosmetics. In the pharmaceutical industry, it enhances the solubility and stability of poorly water-soluble drugs, improving their bioavailability and efficacy while also masking unpleasant tastes. The food sector utilizes it as a stabilizer for flavors, colors, and nutrients, extending shelf life by protecting sensitive ingredients from degradation. In cosmetics, it serves as a complexing agent for fragrances and active components, ensuring their stability and controlled release. Its use expands to many other fields, including nanotechnology for drug delivery systems, environmental remediation for extracting organic pollutants, textiles for slow-release fragrances, and analytical chemistry for chiral separation.

Formula: C₅₆H₉₈O₃₅

Purity: Min. 98%

Color and Shape: White Powder

Molecular weight: 1,331.36 g/mol

Ref: 3D-OD29274

2,6-Di-O-methyl-β-cyclodextrin

CAS: 51166-71-3

Formula: C₅₆H₉₈O₃₅

Purity: >95.0%(HPLC)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 1,331.37

Ref: 3B-D5992

2,6-DI-O-METHYL-β-CYCLODEXTRIN

CAS: 51166-71-3

Purity: 98%

Color and Shape: Solid

Molecular weight: 1331.36499

Ref: 10-F813397