CAS 512-15-2

Cyclopentolate

Description:

Cyclopentolate is a tertiary amine and a derivative of tropic acid, primarily used as a mydriatic agent in ophthalmology to dilate the pupils during eye examinations. It is characterized by its ability to block the action of acetylcholine at the muscarinic receptors in the iris sphincter muscle, leading to pupil dilation. Cyclopentolate is typically administered as an eye drop solution and has a rapid onset of action, with effects lasting several hours. The compound is known for its relatively low systemic absorption, which minimizes side effects. In terms of physical properties, cyclopentolate is a white to off-white crystalline powder that is soluble in water and exhibits a pH-dependent solubility profile. Its chemical structure includes a cyclopentane ring, contributing to its unique pharmacological properties. As with any medication, it is essential to consider potential side effects, including increased intraocular pressure and sensitivity to light, particularly in susceptible individuals.

Formula: C₁₇H₂₅NO₃

InChI: InChI=1S/C17H25NO3/c1-18(2)12-13-21-16(19)15(14-8-4-3-5-9-14)17(20)10-6-7-11-17/h3-5,8-9,15,20H,6-7,10-13H2,1-2H3

InChI key: InChIKey=SKYSRIRYMSLOIN-UHFFFAOYSA-N

SMILES: C(C(OCCN(C)C)=O)(C1(O)CCCC1)C2=CC=CC=C2

Synonyms:

• 1-Hydroxy-α-phenylcyclopentaneacetic acid, 2-(dimethylamino)ethyl ester
• 2-(Dimethylamino)Ethyl (1-Hydroxycyclopentyl)(Phenyl)Acetate
• 2-(Dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate
• 2-Dimethylaminoethyl 1-hydroxy-α-phenylcyclopentaneacetate
• 2-Dimethylaminoethyl 2-(1-Hydroxycyclopentyl)-2-Phenylacetate
• <span class="text-smallcaps">DL</span>-Cyclopentolate
• Benzeneacetic acid, α-(1-hydroxycyclopentyl)-, 2-(dimethylamino)ethyl ester
• Ciclopentolato
• Cyclogyl
• Cyclopentaneacetic acid, 1-hydroxy-α-phenyl-, 2-(dimethylamino)ethyl ester
• Cyclopentoiate
• Cyclopentolat
• Cyclopentylate
• DL-Cyclopentolate
• Tsiklopentolat
• β-Dimethylaminoethyl (1-hydroxycyclopentyl)phenylacetate
• Mydrilate
• 2-Dimethylaminoethyl 1-hydroxy-alpha-phenylcyclopentaneacetate
• 2-dimethylaminoethyl 2-(1-hydroxycyclopentyl)-2-phenyl-ethanoate
• CYCLOPENTOLATE
• Benzeneacetic acid, a-(1-hydroxycyclopentyl)-, 2-(dimethylamino)ethylester
• 1-Hydroxy-alpha-phenylcyclopentaneacetic acid, 2-(dimethylamino)ethyl ester
• 2-(1-hydroxycyclopentyl)-2-phenyl-acetic acid 2-dimethylaminoethyl ester
• yclopentolate
• Benzeneacetic acid, alpha-(1-hydroxycyclopentyl)-, 2-(dimethylamino)ethyl ester
• α-(1-Hydroxycyclopentyl)benzeneacetic acid 2-(dimethylamino)ethyl
• beta-(Dimethylamino)ethyl (1-hydroxycyclopentyl)phenylacetate
• Cyplegin

2-(Dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate

CAS: 512-15-2

Formula: C₁₇H₂₅NO₃

Molecular weight: 291.3853

Ref: IN-DA00I95X

Cyclopentolate

Controlled Product

CAS: 512-15-2

Cyclopentolate is a muscarinic antagonist and is used as an ophthalmic drug to produce mydriasis. Cyclopentolate inhibits the metabolism of cyclopentyl-CoA via the 3-hydroxyacyl-CoA dehydrogenase, which leads to the accumulation of cyclopentyl-CoA in cells. This inhibition can cause metabolic disorders such as hyperlipidemia and diabetes mellitus, which are characterized by increased acid formation and reduced glucose uptake. Cyclopentolate also binds to DNA, inhibiting transcription, replication, and repair of DNA. The binding affinity of cyclopentolate to DNA is approximately 2500 times higher than that of other drugs in its class. Cyclopentolate has been shown to inhibit leukemia inhibitory factor (LIF) and the production of acid from fluorescein angiography

Formula: C₁₇H₂₅NO₃

Purity: Min. 95%

Color and Shape: White/Off-White Solid

Molecular weight: 291.39 g/mol

Ref: 3D-FC61687

2-(Dimethylamino)ethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate

CAS: 512-15-2

Formula: C₁₇H₂₅NO₃

Purity: 95.0%

Molecular weight: 291.391

Ref: 10-F449906