CAS 51336-94-8

2-Chloro-1-(2,4-difluorophenyl)ethanone

Description:

2-Chloro-1-(2,4-difluorophenyl)ethanone, with the CAS number 51336-94-8, is an organic compound characterized by its ketone functional group and the presence of chlorine and fluorine substituents on the aromatic ring. This compound typically appears as a colorless to pale yellow liquid or solid, depending on its purity and temperature. It has a relatively low boiling point, indicative of its volatility, and is soluble in organic solvents such as dichloromethane and acetone, but has limited solubility in water due to its hydrophobic aromatic structure. The presence of the chloro and difluorophenyl groups contributes to its reactivity, making it useful in various chemical syntheses, particularly in the pharmaceutical and agrochemical industries. Additionally, the compound may exhibit biological activity, which can be explored for potential applications in drug development. Safety precautions should be taken when handling this substance, as it may pose health risks due to its chemical properties.

Formula: C₈H₅ClF₂O

InChI: InChI=1S/C8H5ClF2O/c9-4-8(12)6-2-1-5(10)3-7(6)11/h1-3H,4H2

InChI key: InChIKey=UENGBOCGGKLVJJ-UHFFFAOYSA-N

SMILES: C(CCl)(=O)C1=C(F)C=C(F)C=C1

Synonyms:

• 2-Chloro-1-(2,4-difluorophenyl)ethanone
• Chloromethyl(2,4-difluorophenyl) ketone
• Ethanone,2-chloro-1-(2,4-difluorophenyl)-
• α-Chloro-2,4-difluoroacetophenone
• [2-(2,4-difluorophenyl)-2-oxoethyl]chloranuide
• Chloromethyl 2,4-difluorophenyl ketone
• Ethanone, 2-chloro-1-(2,4-difluorophenyl)-
• 2-Chloro-2′,4′-difluoroacetophenone

2-Chloro-2',4'-difluoroacetophenone

CAS: 51336-94-8

Formula: C₈H₅ClF₂O

Purity: >98.0%(GC)

Color and Shape: White to Brown powder to lump

Molecular weight: 190.57

Ref: 3B-C2030

2-Chloro-2',4'-difluoroacetophenone, 98%

CAS: 51336-94-8

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₈H₅ClF₂O

Purity: 98%

Color and Shape: Crystals or powder or crystalline powder, White to pale yellow

Molecular weight: 190.57

Ref: 02-B22487

2-Chloro-1-(2,4-difluorophenyl)ethanone

CAS: 51336-94-8

Formula: C₈H₅ClF₂O

Purity: 97%

Color and Shape: Solid

Molecular weight: 190.57

Ref: 10-F214735

2,4-Difluorophenacyl chloride

CAS: 51336-94-8

2,4-Difluorophenacyl chloride

Formula: C₈H₅ClF₂O

Purity: 98%

Color and Shape: White Solid

Molecular weight: 190.5745

Ref: 54-PC0002

Fluconazole Impurity 6 (2-Chloro-2’,4’-Difluoroacetophenone)

CAS: 51336-94-8

Formula: C₈H₅ClF₂O

Color and Shape: White To Off-White Solid

Molecular weight: 190.57

Ref: 4Z-F-1428

2-Chloro-1-(2,4-difluorophenyl)ethanone

CAS: 51336-94-8

Formula: C₈H₅ClF₂O

Purity: 97%

Color and Shape: Solid

Molecular weight: 190.5745

Ref: IN-DA003374

2-Chloro-2',4'-difluoroacetophenone

Controlled Product

CAS: 51336-94-8

Formula: C₈H₅ClF₂O

Color and Shape: Neat

Molecular weight: 190.57

Ref: 86-MM0235.04

2-Chloro-2',4'-difluoroacetophenone

Controlled Product

CAS: 51336-94-8

Applications A α-haloacetophenone derivatives tested for inhibition of protein tyrosine phosphatases SHP-1 and PTP1B.
References Taylor, S., et al.: Bioorg. Med. Chem., 6, 1457 (1998), Taing, M., et al.: Biochemistry, 38, 3793 (1999), Shen, K., et al.: J. Biol. Chem., 276, 47311 (2001),

Formula: C₈H₅ClF₂O

Color and Shape: Neat

Molecular weight: 190.57

Ref: TR-C365670

2-Chloro-2'',4''-difluoroacetophenone

CAS: 51336-94-8

Formula: C₈H₅ClF₂O

Molecular weight: 190.58

Ref: 7W-GK3806

2-Chloro-2',4'-difluoroacetophenone

CAS: 51336-94-8

2-Chloro-1-(2,4-difluorophenyl)ethanone

Formula: C₈H₅ClF₂O

Purity: 98%

Molecular weight: 190.57

Ref: IN-DG10884

2-Chloro-1-(2,4-difluorophenyl)ethanone

CAS: 51336-94-8

Formula: C₈H₅ClF₂O

Molecular weight: 190.57

Ref: BE-RMCF100020

2-Chloro-2',4'-difluoroacetophenone

CAS: 51336-94-8

2-Chloro-2',4'-difluoroacetophenone (2,4-DFAP) is an asymmetric synthesis of urea nitrogen. It has been shown to be a broad-spectrum antimicrobial, with activity against a number of fungi and bacteria. The molecular modelling of 2,4-DFAP has revealed that it has intramolecular hydrogen bonds and is a supramolecular enantiomer. Additionally, the transport properties have been studied and found to have chloride ions in the molecule. This may be responsible for its anti-fungal effects as well as its ability to inhibit the growth of cryptococcus neoformans.

Formula: C₈H₅ClF₂O

Purity: Min. 95%

Molecular weight: 190.57 g/mol

Ref: 3D-FC20008