CAS 51384-51-1

Metoprolol

Description:

Metoprolol is a selective beta-1 adrenergic receptor blocker primarily used in the treatment of hypertension, angina pectoris, and heart failure. It belongs to the class of medications known as beta-blockers, which work by inhibiting the effects of adrenaline on the heart, leading to a decrease in heart rate and blood pressure. Metoprolol is characterized by its relatively high bioavailability and is often administered in its succinate or tartrate salt forms. The substance is typically well-absorbed from the gastrointestinal tract, with a half-life that allows for once or twice-daily dosing, depending on the formulation. Metoprolol is also known for its ability to cross the blood-brain barrier, which can lead to central nervous system side effects in some patients. Common side effects may include fatigue, dizziness, and bradycardia. As with all medications, it is essential to use metoprolol under medical supervision, considering potential interactions with other drugs and individual patient health conditions.

Formula: C₁₅H₂₅NO₃

InChI: InChI=1S/C15H25NO3/c1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3/h4-7,12,14,16-17H,8-11H2,1-3H3

InChI key: InChIKey=IUBSYMUCCVWXPE-UHFFFAOYSA-N

SMILES: O(CC(CNC(C)C)O)C1=CC=C(CCOC)C=C1

Synonyms:

• (RS)-Metoprolol
• 1-(Isopropilamino)-3-[4-(2-Metoxietil)Fenoxi]Propan-2-Ol
• 1-(Isopropylamino)-3-[4-(2-Methoxyethyl)Phenoxy]Propan-2-Ol
• 1-(Isopropylamino)-3-[4-(2-Methoxyethyl)Phenoxy]Propane-2-Ol
• 1-(Isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]-2-propanol
• 1-(Isopropylamino)-3-[p-(2-methoxyethyl)phenoxy]-2-propanol
• 1-[4-(2-Methoxyethyl)Phenoxy]-3-(Propan-2-Ylamino)Propan-2-Ol 2,3-Dihydroxybutanedioate (1:1)
• 1-[4-(2-Methoxyethyl)Phenoxy]-3-Propan-2-Ylamino-Propan-2-Ol
• 1-[4-(2-Methoxyethyl)Phenoxy]-3-[(1-Methylethyl)Amino]Propan-2-Ol 2,3-Dihydroxybutanedioate (Salt)
• 1-[4-(2-Methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-2-propanol
• 2-Propanol, 1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-
• Beatrolol
• Betaloc
• Cgp 2175
• Meijoprolol
• Metocard
• Metohexal
• Metroprolol
• Seroken
• Spesicor
• Toprol
• Vazocardin
• [2-Hydroxy-3-[4-(2-methoxyethyl)phenoxy]propyl](propan-2-yl)amine
• dl-Metoprolol

Metoprolol Tartrate

CAS: 51384-51-1, 56392-17-7

Formula: C₁₅H₂₅NO₃C₄H₆O₆

Purity: >98.0%(T)(HPLC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 342.41

Ref: 3B-M2555

rac Metoprolol

CAS: 51384-51-1

Applications rac Metoprolol is a β1 selective aryloxypropanolamine andrenergic antagonist. Used in the treatment of a variety of cardiovascular disorder.
References McGourty, J.C., et al.: Br. J. Clin. Pharmacol. 20, 555 (1985); Lennard, M.S., et al.: Biochem. Pharmacol., 35, 2757 (1986)

Formula: C₁₅H₂₅NO₃

Color and Shape: White To Off-White

Molecular weight: 267.36

Ref: TR-M338815

(R)-Metoprolol

Controlled Product

CAS: 51384-51-1

Applications (R)-Enantiomer of Metoprolol. Antihypertensive; antianginal; antiarrhythmic (class II).
References Johansson, et al.: Eur. J. Pharmacol., 24, 194 (1973), Luch, J.R., et al.: Anal. Profiles Drug Subs., 12, 325 (1983), Benfield, P., et al.: Drugs, 31, 376 (1986),

Formula: C₁₅H₂₅NO₃

Color and Shape: Neat

Molecular weight: 267.36

Ref: TR-M338775

Metoprolol

Controlled Product

CAS: 51384-51-1

Metoprolol is a drug that belongs to the group of beta-adrenergic blockers. It is used in the treatment of hypertension, angina pectoris, and heart attack. Metoprolol has been shown to be effective in treating congestive heart failure, high blood pressure and angina pectoris. Metoprolol slows down the heart rate by blocking beta-adrenergic receptors and also decreases the force with which the heart contracts. Metoprolol is not recommended for use in people with liver impairment or severe renal impairment because it can result in hypotension. This drug should not be taken by people who have asthma or suffer from chronic obstructive pulmonary disease (COPD) or who are allergic to metoprolol succinate.

Formula: C₁₅H₂₅NO₃

Purity: Min. 95%

Molecular weight: 267.36 g/mol

Ref: 3D-BCA38451