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CAS 56392-17-7

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Metoprolol tartrate

Description:
Metoprolol tartrate is a selective beta-1 adrenergic antagonist, primarily used in the treatment of hypertension, angina pectoris, and heart failure. It is a white to off-white crystalline powder that is soluble in water and methanol, with a molecular formula that reflects its composition of carbon, hydrogen, nitrogen, and oxygen. The substance acts by blocking beta-1 receptors in the heart, leading to a decrease in heart rate and myocardial contractility, which ultimately reduces cardiac workload and oxygen demand. Metoprolol tartrate is often administered orally and is known for its relatively rapid onset of action. Its pharmacokinetics include extensive first-pass metabolism, which affects its bioavailability. The drug is generally well-tolerated, though it may cause side effects such as fatigue, dizziness, or bradycardia. As with any medication, it is important to use metoprolol tartrate under medical supervision to manage potential interactions and contraindications effectively.
Formula:C15H25NO3C4H6O6
InChI:InChI=1S/C15H25NO3.C4H6O6/c1-12(2)16-10-14(17)11-19-15-6-4-13(5-7-15)8-9-18-3;5-1(3(7)8)2(6)4(9)10/h4-7,12,14,16-17H,8-11H2,1-3H3;1-2,5-6H,(H,7,8)(H,9,10)/t;1-,2-/m.1/s1
InChI key:InChIKey=WPTKISQJQVFSQI-LREBCSMRSA-N
SMILES:O(CC(CNC(C)C)O)C1=CC=C(CCOC)C=C1.[C@@H]([C@H](C(O)=O)O)(C(O)=O)O
Synonyms:
  • (±)-1-(Isopropylamino)-3-[4-(2-methoxyethyl)phenoxy]-2-propanol tartrate
  • (±)-Metoprolol bitartrate
  • (±)Metoprolol-(+)-tartarate salt
  • 2-Propanol, 1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-, (2R,3R)-2,3-dihydroxybutanedioate (2:1)
  • 2-Propanol, 1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-, (2R,3R)-2,3-dihydroxybutanedioate (2:1) (salt)
  • 2-Propanol, 1-[4-(2-methoxyethyl)phenoxy]-3-[(1-methylethyl)amino]-, (±)-, [R-(R*,R*)]-2,3-dihydroxybutanedioate (2:1) (salt)
  • Beloc
  • Betaloc
  • Cgp 2175E
  • H 93/26
  • See more synonyms
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