CAS 5146-68-9

N-(Hydroxymethyl)succinimide

Description:

N-(Hydroxymethyl)succinimide, with the CAS number 5146-68-9, is an organic compound characterized by its structure, which includes a succinimide ring with a hydroxymethyl group attached. This compound is typically a white to off-white crystalline solid and is soluble in polar solvents such as water and alcohols. It is known for its role as a reagent in organic synthesis, particularly in the preparation of various derivatives and in the modification of biomolecules. The presence of the hydroxymethyl group enhances its reactivity, making it useful in coupling reactions and as a potential building block in pharmaceuticals and agrochemicals. Additionally, N-(Hydroxymethyl)succinimide can exhibit properties such as low toxicity and stability under standard laboratory conditions, although it should be handled with care due to potential reactivity. Its applications extend to fields such as medicinal chemistry and materials science, where it serves as an intermediate in the synthesis of more complex molecules.

Formula: C₅H₇NO₃

InChI: InChI=1S/C5H7NO3/c7-3-6-4(8)1-2-5(6)9/h7H,1-3H2

InChI key: InChIKey=AZVYYSCOCHRFKW-UHFFFAOYSA-N

SMILES: C(O)N1C(=O)CCC1=O

Synonyms:

• 1-(Hydroxymethyl)-2,5-pyrrolidinedione
• 2,5-Pyrrolidinedione, 1-(Hydroxymethyl)-
• N-(Hydroxymethyl)succinimide
• N-Hydroxy-methyl-succinimid
• N-Methylolsuccinimide
• NSC 27352
• Succinimide, N-(hydroxymethyl)-

1-(Hydroxymethyl)pyrrolidine-2,5-dione

CAS: 5146-68-9

1-(Hydroxymethyl)pyrrolidine-2,5-dione

Formula: C₅H₇NO₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 129.11

Ref: 54-OR95812

N-(Hydroxymethyl)succinimide

CAS: 5146-68-9

Formula: C₅H₇NO₃

Purity: 97%

Color and Shape: Solid

Molecular weight: 129.1140

Ref: IN-DA006VVI

N-hydroxymethyl succinimide

CAS: 5146-68-9

1-(Hydroxymethyl)pyrrolidine-2,5-dione

Formula: C₅H₇NO₃

Purity: 95+%

Molecular weight: 129.11

Ref: IN-DG234884

1-(Hydroxymethyl)pyrrolidine-2,5-dione

CAS: 5146-68-9

Purity: 97%

Molecular weight: 129.1150055

Ref: 10-F640985

1-(Hydroxymethyl)pyrrolidine-2,5-dione

CAS: 5146-68-9

1-(Hydroxymethyl)pyrrolidine-2,5-dione is an organic compound that has been shown to be a potent inhibitor of the cyclooxygenase (COX) enzyme. It is also a precursor in the synthesis of aspirin. This chemical has been shown to be an effective inhibitor of COX and other enzymes in vitro. 1-(Hydroxymethyl)pyrrolidine-2,5-dione was found to be stable in acidic conditions and can be used as a model for this type of environment. 1-(Hydroxymethyl)pyrrolidine-2,5-dione is not absorbed from the gastrointestinal tract and must be given by injection or intravenously. The pharmacokinetic profile of this drug has been studied using animal models and microscopy techniques on intestinal tissue.

Formula: C₅H₇NO₃

Purity: Min. 95%

Molecular weight: 129.11 g/mol

Ref: 3D-FAA14668

N-Hydroxymethyl succinimide

CAS: 5146-68-9

N-Hydroxymethyl succinimide (N-Methylolsuccinimide) serves as a carrier molecule for prodrugs of non-steroidal anti-inflammatory drugs (NSAIDs). It enhances the lipophilicity of NSAIDs and reduces their gastrointestinal toxicity. N-Hydroxymethyl succinimide is promising for research in anti-inflammatory drug delivery systems.

Formula: C₅H₇NO₃

Color and Shape: Solid

Molecular weight: 129.114

Ref: TM-TCL-01969