CAS 51481-61-9
:Cimetidine
Description:
Cimetidine is a histamine H2 receptor antagonist primarily used to reduce stomach acid production, making it effective in treating conditions such as peptic ulcers, gastroesophageal reflux disease (GERD), and Zollinger-Ellison syndrome. Its chemical formula is C10H13N5S, and it features a thiourea group, which is crucial for its pharmacological activity. Cimetidine is known for its ability to inhibit gastric acid secretion by blocking the action of histamine at the H2 receptors on parietal cells in the stomach lining. Additionally, it has a relatively short half-life and is metabolized in the liver, with some potential for drug interactions due to its effect on cytochrome P450 enzymes. Common side effects may include dizziness, headache, and gastrointestinal disturbances. Cimetidine is also notable for its anti-androgenic effects, which can lead to gynecomastia in some patients. Overall, it remains a significant medication in the management of acid-related disorders, although newer agents with fewer side effects are often preferred in clinical practice.
Formula:C10H16N6S
InChI:InChI=1/C10H16N6S/c1-8-9(16-7-15-8)5-17-4-3-13-10(12-2)14-6-11/h7H,3-5H2,1-2H3,(H,15,16)(H2,12,13,14)
InChI key:InChIKey=AQIXAKUUQRKLND-UHFFFAOYSA-N
SMILES:C(SCCN=C(NC#N)NC)C1=C(C)N=CN1
Synonyms:- 1-Cyano-2-methyl-3-[2-[(5-methyl-1H-imidazol-4-yl)methylsulfanyl]ethyl]guanidine
- 2-Cyano-1-Methyl-3-(2-(((5-Methylimidazol-4-Yl)Methyl)Thio)Ethyl)Guanidine
- Acibilin
- Acinil
- Biomet
- Cimal
- Cimetag
- Cimetidin
- Cimetidina
- Cimetidine (base or and unspecifieds salts)
- Cimetidine A
- Cimetidine AB
- Cimetum
- Dyspamet
- Edalene
- Eureceptor
- Fremet
- Gastromet
- Guanidine, N-cyano-N'-methyl-N''-[2-[[(5-methyl-1H-imidazol-4-yl)methyl]thio]ethyl]-
- Guanidine, N-cyano-N'-methyl-N''-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]-
- Histodil
- N-Cyano-N'-methyl-N''-[2-((4-methyl-5-imidazolyl)-methylthio)ethyl]guanidine
- N-Cyano-N′′-methyl-N′-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]guanidine
- Nsc 335308
- Peptol
- Skf 92334
- Tagamet
- Tagamet HB
- Tagamet HB 200
- Tamagret
- Tametin
- Tratul
- Ulcedin
- Ulcedine
- Ulcerex
- Ulcerfen
- Ulcimet
- Ulcofalk
- Ulcomedina
- Ulcomet
- Ulhys
- Cimetidine
- CIMETIDINE A TYPE
- FPF 1002
- N-CYANO-N'-METHYL-N''-[[2-[(5-METHYL-1H-IMIDAZOL-4-YL)METHYL]THIO]ETHYL]GUANIDINE
- CIMITIDINE
- ALTRAMET
- 2-CYANO-1-METHYL-3-[2-(5-METHYL-1H-IMIDAZOL-4-YL-METHYLTHIO)ETHYL]GUANIDINE
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Found 22 products.
Cimetidine
CAS:Formula:C10H16N6SPurity:>99.0%(T)(HPLC)Color and Shape:White to Almost white powder to crystalMolecular weight:252.34Cimetidine, 98+%
CAS:<p>Widely used H2 histamine antagonist which has more recently been described as an inverse agonist. Also a potent I1 imidazoline binding site ligand. It displays antitumor and immunomodulatory activity. Cimetidine competitively inhibits histamine binding to histamine H2 receptors, and suppresses the g</p>Formula:C10H16N6SPurity:98+%Color and Shape:White to off-white, PowderMolecular weight:252.34CIMETIDINE FOR PEAK IDENTIFICATION CRS
CAS:<p>CIMETIDINE FOR PEAK IDENTIFICATION CRS</p>Formula:C10H16N6SMolecular weight:252.3392Cimetidine
CAS:CimetidineFormula:C10H16N6SPurity:99.6%Color and Shape:White SolidMolecular weight:252.11572Cimetidine
CAS:<p>Compounds containing an unfused imidazole ring, whether or not hydrogenated, in the structure, nesoi</p>Formula:C10H16N6SColor and Shape:White Off-White Crystalline PowderMolecular weight:252.11572(Z)-3-cyano-1-methyl-2-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine
CAS:Formula:C10H16N6SPurity:98%Color and Shape:SolidMolecular weight:252.3392Cimetidine
CAS:<p>Cimetidine (SKF-92334) is a histamine congener, it competitively inhibits HISTAMINE binding to HISTAMINE H2 RECEPTORS.</p>Formula:C10H16N6SPurity:99.82%Color and Shape:Crystals Physical Description White Crystals With A Slight Sulfur-Mercaptan Odor (Ntp 1992)Molecular weight:252.34Cimetidine, USP grade
CAS:Formula:C10H16N6SPurity:≤ 0.2%Color and Shape:White crystalline powderMolecular weight:252.34Cimetidine
CAS:Formula:C10H16N6SPurity:99.0 - 101.0 %Color and Shape:White to off-white powderMolecular weight:252.34Cimetidine 100 µg/mL in Acetonitrile
CAS:Formula:C10H16N6SColor and Shape:Single SolutionMolecular weight:252.34Cimetidine
CAS:<p>Cimetidine is a histamine-2 receptor antagonist that inhibits gastric acid secretion and reduces the activity of stomach enzymes. It is used to treat peptic ulcers, gastroesophageal reflux disease, and Zollinger-Ellison syndrome. Cimetidine has been shown to inhibit the activity of drug-metabolizing enzymes such as cytochrome P450. Cimetidine also inhibits the transport protein P-glycoprotein (P-gp), which leads to increased concentrations of some drugs in the blood and tissues. This inhibition may lead to an increase in cardiac effects with certain drugs, such as x-ray diffraction data with taxol or h1 antagonists.</p>Formula:C10H16N6SPurity:Min. 95%Color and Shape:White PowderMolecular weight:252.34 g/molN-Cyano-N’-methyl-N”-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]guanidine
CAS:Formula:C10H16N6SPurity:98%Color and Shape:SolidMolecular weight:252.34
![(Z)-3-cyano-1-methyl-2-(2-{[(5-methyl-1H-imidazol-4-yl)methyl]sulfanyl}ethyl)guanidine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2FIN%2Fthumb%2FDA00I97O.jpg&w=3840&q=75)
![N-Cyano-N’-methyl-N”-[2-[[(4-methyl-1H-imidazol-5-yl)methyl]thio]ethyl]guanidine](/_next/image/?url=https%3A%2Fstatic.cymitquimica.com%2Fproducts%2F10%2Fthumb%2FF224139.jpg&w=3840&q=75)
