CAS 515-03-7

Sclareol

Description:

Sclareol is a natural organic compound classified as a sesquiterpene alcohol, primarily derived from the plant Salvia sclarea, commonly known as clary sage. It has a molecular formula of C15H26O and features a complex structure characterized by multiple rings and a hydroxyl functional group. Sclareol is known for its pleasant, sweet, and woody aroma, making it valuable in the fragrance and flavor industries. It is often used as a fixative in perfumes and as a flavoring agent in food products. Additionally, sclareol exhibits potential biological activities, including antimicrobial and anti-inflammatory properties, which have garnered interest in pharmaceutical research. The compound is typically obtained through steam distillation of clary sage oil or synthesized in the laboratory. Sclareol is generally recognized as safe for use in cosmetics and food, although its concentration and application are regulated. Its unique properties and versatility make it an important compound in various industrial applications.

Formula: C₂₀H₃₆O₂

InChI: InChI=1S/C20H36O2/c1-7-18(4,21)13-9-16-19(5)12-8-11-17(2,3)15(19)10-14-20(16,6)22/h7,15-16,21-22H,1,8-14H2,2-6H3/t15-,16+,18-,19-,20+/m0/s1

InChI key: InChIKey=XVULBTBTFGYVRC-HHUCQEJWSA-N

SMILES: C[C@]12[C@@](CC[C@@](C)(O)[C@@H]1CC[C@@](C=C)(C)O)(C(C)(C)CCC2)[H]

Synonyms:

• (13R)-Labd-14-Ene-13-Diol
• (1R,2R,4aS,8aS)-1-[(3R)-3-hydroxy-3-methylpent-4-en-1-yl]-2,5,5,8a-tetramethyldecahydronaphthalen-2-ol
• (1R,2R,8As)-Decahydro-1-(3-Hydroxy-3-Methyl-4-Pentenyl)-2,5,5,8A-Tetramethyl-2-Naphthol
• (1R,2R,8aS)-1-[(3R)-3-hydroxy-3-methylpent-4-en-1-yl]-2,5,5,8a-tetramethyldecahydronaphthalen-2-ol
• (1R-(1-Alpha(R*),2-Beta,4A-Beta,8A-Alpha))-Thyl
• (αR,1R,2R,4aS,8aS)-α-Ethenyldecahydro-2-hydroxy-α,2,5,5,8a-pentamethyl-1-naphthalenepropanol
• .alpha.-ethenyldecahydro-2-hydroxy-.alpha.,2,5,5,8a-pentamethyl-,[1R-[1.alpha.(R*),2.beta.,4a.beta1-Naphthalenepropanol
• 1-(3-Hydroxy-3-methyl-4-pentenyl)-2,5,5,8a-tetramethyldecahydro-2-naphthalenol
• 1-Naphthalenepropanol, alpha-ethenyldecahydro-2-hydroxy-alpha,2,5,5,8a-pentamethyl-, [1R-[1alpha(R*),2beta,4abeta,8aalpha]]-
• 1-Naphthalenepropanol, α-ethenyldecahydro-2-hydroxy-α,2,5,5,8a-pentamethyl-, (αR,1R,2R,4aS,8aS)-
• 1-Naphthalenepropanol, α-ethenyldecahydro-2-hydroxy-α,2,5,5,8a-pentamethyl-, [1R-[1α(R*),2β,4aβ,8aα]]-
• Labd-14-ene-8,13-diol, (13R)-
• [1Theta-[1Alpha(Theta),2Beta,4Abeta,8Aalpha]]-Thyl

Sclareol

CAS: 515-03-7

Formula: C₂₀H₃₆O₂

Purity: >96.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 308.51

Ref: 3B-S0916

(1R,2R,4aS,8aS)-1-[(3R)-3-hydroxy-3-methylpent-4-en-1-yl]-2,5,5,8a-tetramethyl-decahydronaphthalen-2-ol

CAS: 515-03-7

Formula: C₂₀H₃₆O₂

Purity: 97%

Color and Shape: Solid

Molecular weight: 308.4986

Ref: IN-DA003U7W

Sclareol

CAS: 515-03-7

Sclareol

Formula: C₂₀H₃₆O₂

Purity: 98%

Color and Shape: Solid

Molecular weight: 308.5

Ref: 54-OR1029823

Sclareol

CAS: 515-03-7

Sclareol

Formula: C₂₀H₃₆O₂

Purity: ≥98%

Molecular weight: 308.5

Ref: 54-BUP15766

Sclareol

CAS: 515-03-7

Formula: C₂₀H₃₆O₂

Purity: 95%~99%

Molecular weight: 308.506

Ref: BP-BP1270

Sclareol

CAS: 515-03-7

Formula: C₂₀H₃₆O₂

Molecular weight: 308.51

Ref: 4Z-S-271001

Sclareol

CAS: 515-03-7

Formula: C₂₀H₃₆O₂

Purity: (GC) ≥ 96.0%

Color and Shape: White to almost white powder or crystals

Molecular weight: 308.50

Ref: 7W-GP0437

Sclareol

CAS: 515-03-7

Sclareol from clary sage inhibits growth and is cytotoxic to many human Y cell lines.

Formula: C₂₀H₃₆O₂

Purity: 99.58% - 99.97%

Color and Shape: White Fine Powder

Molecular weight: 308.5

Ref: TM-T3020

Sclareol (~90%)

CAS: 515-03-7

Applications Sclareol is used in biological studies as it has anti-inflammatory activity in both lipopolysaccharide-stimulated macophages and λ-carrageenan-induced paw edema model.
References Huang, G., et al.: J. Nat. Prod., 75, 54 (2012); Weninger, S., et al.: Nat. Med 7, 527 (2001)

Formula: C₂₀H₃₆O₂

Purity: ~90%

Color and Shape: Neat

Molecular weight: 308.5

Ref: TR-S199970

Sclareol

CAS: 515-03-7

Sclareol is a compound that is found in the essential oil of clary sage. It has been shown to have significant cytotoxic effects on cancer cells, as it inhibits cellular proliferation and induces apoptosis by inhibiting mitochondrial membrane potential and ATP production. Sclareol also has antibacterial and antifungal properties. Sclareol can inhibit the growth of Candida glabrata yeast at concentrations of 10-5M or less. This compound has also been shown to be effective against other pathogens such as Mycobacterium tuberculosis, Helicobacter pylori, and Escherichia coli.

Formula: C₂₀H₃₆O₂

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 308.5 g/mol

Ref: 3D-FS74088

SCLAREOL

CAS: 515-03-7

Purity: 98%(GC-MS);RG

Molecular weight: 308.506012

Ref: 10-F859360