CAS 51529-01-2

Flupenthixol dihydrochloride

Description:

Flupenthixol dihydrochloride is an antipsychotic medication primarily used in the treatment of schizophrenia and other mental health disorders. It belongs to the thioxanthene class of drugs and functions as a dopamine receptor antagonist, particularly targeting D2 receptors in the brain. This compound is characterized by its ability to alleviate symptoms of psychosis, including hallucinations and delusions, while also exhibiting anxiolytic and antidepressant properties. Flupenthixol dihydrochloride is typically administered in the form of oral tablets or injectable formulations, allowing for flexibility in treatment regimens. The dihydrochloride salt form enhances its solubility and bioavailability. Common side effects may include sedation, weight gain, and extrapyramidal symptoms, which are typical of many antipsychotic medications. Due to its pharmacological profile, it is essential for healthcare providers to monitor patients for potential adverse effects and adjust dosages accordingly. Overall, flupenthixol dihydrochloride is a valuable therapeutic option in managing severe psychiatric conditions, contributing to improved patient outcomes when used appropriately.

Formula: C₂₃H₂₇Cl₂F₃N₂OS

InChI: InChI=1/C23H25F3N2OS.2ClH/c24-23(25,26)17-7-8-22-20(16-17)18(19-4-1-2-6-21(19)30-22)5-3-9-27-10-12-28(13-11-27)14-15-29;;/h1-2,4-8,16,29H,3,9-15H2;2*1H/b18-5+;;

InChI key: IOVDQEIIMOZNNA-MHKBYHAFSA-N

SMILES: C1CN(CCN1CC/C=C\2/C3=CC=CC=C3SC4=C2C=C(C=C4)C(F)(F)F)CCO.Cl.Cl

Synonyms:

• cis-(Z)-Flupenthixol dihydrochloride
• (Z)-4-[3-[2-(Trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl]-1-piperazineethanol dihydrochloride
• 2-(4-{(3E)-3-[2-(trifluoromethyl)-9H-thioxanthen-9-ylidene]propyl}piperazin-1-yl)ethanol dihydrochloride

cis-(Z)-Flupentixol dihydrochloride

CAS: 51529-01-2

Purity: 98%

Ref: IN-DA00DDSE

Flupenthixol Dihydrochloride

CAS: 51529-01-2

Flupenthixol Dihydrochloride

Formula: C₂₃H₂₇Cl₂F₃N₂OS

Purity: ≥98%

Molecular weight: 507.44

Ref: 54-PC109003

cis-(Z)-Flupentixol dihydrochloride

CAS: 51529-01-2

cis-(Z)-Flupentixol dihydrochloride (Emergil) is a dopamine receptor antagonist.

Formula: C₂₃H₂₇Cl₂F₃N₂OS

Purity: 98.07%

Color and Shape: Solid

Molecular weight: 507.44

Ref: TM-T2564

cis-(Z)-Flupentixol Dihydrochloride

Controlled Product

CAS: 51529-01-2

Applications Neuroleptic agent related structurally to thiothixene. Antipsychotic; neuroleptic agent; dopamine receptor antagonist.
References Nielsen, et al.: Acta Pharmacol. Toxicol., 32, 363 (1973), Post, M.L., et al.: Nature, 256, 342 (1975), Peuch, et al.: Neuropharmacology, 20, 1279 (1981),

Formula: C₂₃H₂₇Cl₂F₃N₂OS

Color and Shape: Neat

Molecular weight: 507.44

Ref: TR-F597980