CAS 51805-45-9

Tris-(2-carboxyethyl)-phosphine hydrochloride

Description:

Tris-(2-carboxyethyl)-phosphine hydrochloride, commonly referred to as TCEP hydrochloride, is a water-soluble phosphine compound with the CAS number 51805-45-9. It is characterized by its ability to act as a reducing agent, particularly in biochemical applications, where it is often used to maintain proteins in their reduced state by preventing oxidation. TCEP hydrochloride is stable under a wide range of pH conditions and does not react with thiol groups, making it a preferred choice over other reducing agents like dithiothreitol (DTT) or β-mercaptoethanol, which can introduce unwanted side reactions. The compound is typically supplied as a white to off-white crystalline powder and is soluble in water, allowing for easy incorporation into various biochemical assays. Additionally, TCEP hydrochloride is non-toxic and does not have the unpleasant odor associated with some other reducing agents, enhancing its usability in laboratory settings. Its unique properties make it valuable in protein chemistry, particularly in studies involving disulfide bond reduction and protein folding.

Formula: C₉H₁₂O₆P

InChI: InChI=1/C9H15O6P/c10-7(11)1-4-16(5-2-8(12)13)6-3-9(14)15/h1-6H2,(H,10,11)(H,12,13)(H,14,15)/p-3

SMILES: C(CP(CCC(=O)[O-])CCC(=O)[O-])C(=O)[O-]

Synonyms:

• 3,3',3''-Phosphanetriyltripropanoic Acid Hydrochloride
• 3,3',3''-Phosphanetriyltripropanoate

Tris(2-carboxyethyl)phosphine Hydrochloride

CAS: 51805-45-9

Formula: C₉H₁₅O₆P·HCl

Purity: >98.0%(T)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 286.64

Ref: 3B-T1656

Tris(2-carboxyethyl)phosphine hydrochloride, 98%, Molecular Biology Grade

CAS: 51805-45-9

Tris(2-carboxyethyl)phosphine hydrochloride, 98%, Molecular Biology Grade

Formula: C₉H₁₂O₆P

Purity: 98%

Color and Shape: Crystalline powder or powder or crystals or solid, White

Molecular weight: 247.16

Ref: 02-J60316

Tris(2-carboxyethyl)phosphine hydrochloride, 95%, 0.5M soln. in water

CAS: 51805-45-9

Tris(2-carboxyethyl)phosphine hydrochloride is widely used as a reducing agent to reduce disulfide bonds in proteins and trans-4,5-dihydroxy-1,2-dithiane. It is involved in the reduction of sulfoxides, sulfonyl chlorides, N-oxides and azides. It plays an important role in the tissue homogenization p

Formula: C₉H₁₂O₆P

Purity: 95%

Molecular weight: 247.16

Ref: 02-H51864

Tris(2-carboxyethyl)phosphine hydrochloride, 98%

CAS: 51805-45-9

Reducing agent, specific for disulfides

Formula: C₉H₁₂O₆P

Purity: 98%

Color and Shape: Crystals or powder or crystalline powder, White to pale cream or pale yellow

Molecular weight: 247.16

Ref: 02-040587

Tris(2-carboxyethyl)phosphine, hydrochloride, 99% TCEP

CAS: 51805-45-9

Tris(2-carboxyethyl)phosphine, hydrochloride, 99% TCEP

Formula: (HOOCCH₂CH₂)₃PHCl

Purity: 99%

Color and Shape: white xtl.

Molecular weight: 286.65

Ref: 08-15-7400

3,3',3''-Phosphinetriyltripropanoic acid hydrochloride

CAS: 51805-45-9

Formula: C₉H₁₆ClO₆P

Purity: 97%

Color and Shape: Solid

Molecular weight: 286.6465

Ref: IN-DA003V70

TCEP hydrochloride, 0.5M in water, pH 7

CAS: 51805-45-9

Formula: C₉H₁₅O₆P·HCl

Color and Shape: Clear, colourless liquid

Molecular weight: 286.65

Ref: 7W-GE4909

Tris-(2-carboxyethyl)phosphine hydrochloride

CAS: 51805-45-9

Formula: C₉H₁₅O₆P·HCl

Purity: ≥ 98.0%

Color and Shape: White crystalline powder

Molecular weight: 286.65

Ref: 7W-GE1860

TCEP hydrochloride

CAS: 51805-45-9

TCEP hydrochloride

Purity: ≥98%

Molecular weight: 286.65g/mol

Ref: 54-BUP16797

Tris(2-carboxyethyl)phosphine hydrochloride

CAS: 51805-45-9

Tris(2-carboxyethyl)phosphine hydrochloride

Formula: C₉H₁₅O₆P·ClH

Purity: 98%

Color and Shape: white to off white solid

Molecular weight: 286.6465g/mol

Ref: 54-BIT0122

TCEP Hydrochloride [for Electrophoresis]

CAS: 51805-45-9

Formula: C₉H₁₅O₆P·HCl

Purity: >98.0%(T)

Color and Shape: White to Light yellow powder to crystal

Molecular weight: 286.64

Ref: 3B-T4134

TCEP HCl

CAS: 51805-45-9

M02624 - TCEP HCl

Formula: C₉H₁₆ClO₆P

Purity: 98%

Color and Shape: Solid, Powder or Crystalline Powder

Molecular weight: 286.64

Ref: 10-M02624

TCEP hydrochloride

CAS: 51805-45-9

TCEP hydrochloride (Tris(2-carboxyethyl)phosphine hydrochloride) is a non-thiol-reducing agent that selectively reduces proteolysis. Cost-effective and quality-assured.

Formula: C₉H₁₆ClO₆P

Purity: 99.56% - 99.93%

Color and Shape: White Crystalline Solid

Molecular weight: 286.65

Ref: TM-T7087

TCEP Hydrochloride

CAS: 51805-45-9

Applications Biochemical tool for selective reduction of disulfide bridges at low pH; reductant for redox assay.
Not a dangerous good if item is equal to or less than 1g/ml and there is less than 100g/ml in the package
References Neuburger, M., et al.: Eur. J. Biochem., 267, 2882 (2000), Krijt, J., et al.: Clin. Chem., 47, 1821 (2001), Yen, T.-Y., et al.: J. Mass Spectrom., 37, 15 (2002),

Formula: C₉H₁₅O₆P·ClH

Color and Shape: Neat

Molecular weight: 286.65

Ref: TR-T012500

TCEP Hydrochloride (0.5M in water)

Controlled Product

CAS: 51805-45-9

Formula: C₉H₁₅O₆P·ClH

Color and Shape: Colourless

Molecular weight: 286.65

Ref: TR-T012515

Tris-(2-carboxyethyl)phosphine hydrochloride

CAS: 51805-45-9

Tris(carboxyethyl)phosphine·HCl, also known as TCEP·HCl, is used to reduce disulfide bonds in protein samples. TCEP·HCl presents numerous advantages over the commonly used DTT and DTE: it is faster, stable to oxygen and metals, and appears as a non-volatile odourless solid. Furthermore, TCEP·HCl can be used at a broader pH range compared to DTT and DTE.

Formula: C₉H₁₆ClO₆P

Molecular weight: 286.65 g/mol

Ref: 3D-C-1818

Tris(2-carboxyethyl) Phosphine Hydrochloride (TCEP) extrapure AR, 98%

CAS: 51805-45-9

Formula: C₉H₁₅O₆P·HCl

Purity: min. 98%

Color and Shape: White, Crystalline powder

Molecular weight: 286.65

Ref: SR-55664