CAS 51926-51-3

L-Prolyl-L-isoleucine

Description:

L-Prolyl-L-isoleucine, with the CAS number 51926-51-3, is a dipeptide composed of the amino acids proline and isoleucine. This compound is characterized by its unique structure, where proline, a cyclic amino acid, contributes to the rigidity and stability of the peptide chain. The presence of isoleucine, a branched-chain amino acid, adds hydrophobic characteristics, influencing the compound's solubility and interaction with biological systems. L-Prolyl-L-isoleucine is known for its potential biological activities, including roles in protein synthesis and modulation of metabolic processes. It may also exhibit specific interactions with receptors or enzymes, contributing to its physiological effects. The compound is typically studied in the context of peptide synthesis and may have applications in pharmaceuticals or nutritional supplements. Its stability, solubility, and bioactivity are influenced by the specific arrangement of its amino acid components, making it a subject of interest in biochemical research.

Formula: C₁₁H₂₀N₂O₃

InChI: InChI=1S/C11H20N2O3/c1-3-7(2)9(11(15)16)13-10(14)8-5-4-6-12-8/h7-9,12H,3-6H2,1-2H3,(H,13,14)(H,15,16)/t7-,8-,9-/m0/s1

InChI key: InChIKey=OCYROESYHWUPBP-CIUDSAMLSA-N

SMILES: [C@H](NC(=O)[C@@H]1CCCN1)([C@H](CC)C)C(O)=O

Synonyms:

• 2003: PN: EP2071334 SEQID: 2112 claimed protein
• 2003: PN: WO2009077864 SEQID: 2112 claimed protein
• 377: PN: EP2161028 PAGE: 14 claimed protein
• 452: PN: WO2005081628 SEQID: 454 claimed protein
• <span class="text-smallcaps">L</smallcap>-Isoleucine, <smallcap>L</span>-prolyl-
• <span class="text-smallcaps">L</smallcap>-Isoleucine, N-<smallcap>L</span>-prolyl-
• <span class="text-smallcaps">L</smallcap>-Prolyl-<smallcap>L</span>-isoleucine
• H-Pro-Ile-OH
• L-Prolyl-L-isoleucine
• L-prolyl-L-alloisoleucine
• L-Isoleucine, L-prolyl-

H-Pro-Ile-OH

CAS: 51926-51-3

Specific inhibitor of rat endopeptidase 24.16 (oligopeptidase M, neurolysin).

Formula: C₁₁H₂₀N₂O₃

Purity: > 99%

Color and Shape: White Crystalline Powder

Molecular weight: 228.29

Ref: 01-4001060

H-Pro-Ile-OH

CAS: 51926-51-3

Formula: C₁₁H₂₀N₂O₃

Purity: 95%

Molecular weight: 228.2881

Ref: IN-DA00DCB9

L-Prolyl-L-isoleucine

Controlled Product

CAS: 51926-51-3

Formula: C₁₁H₂₀N₂O₃

Color and Shape: White To Off-White

Molecular weight: 228.288

Ref: TR-P839973

H-Pro-Ile-OH

CAS: 51926-51-3

H-Pro-Ile-OH is an amino acid that is found in the mitochondria of cells. It is a prodrug that binds to angiotensin and blocks its conversion to angiotensin II, which has been shown to have blood pressure lowering effects. H-Pro-Ile-OH has been shown to be a competitive inhibitor of oligopeptidase, with a half maximal inhibitory concentration (IC50) of 0.5 mM, and has also been shown to have antihypertensive properties.

Formula: C₁₁H₂₀N₂O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 228.29 g/mol

Ref: 3D-FP108157

Prolylisoleucine

CAS: 51926-51-3

Prolylisoleucine is a derivative of isoleucine that is used in the biosynthesis of proteins.

Formula: C₁₁H₂₀N₂O₃

Color and Shape: Solid

Molecular weight: 228.29

Ref: TM-T34140