CAS 522-97-4

(±)-Tetrahydroberberine

Description:

(±)-Tetrahydroberberine is a chemical compound that belongs to the class of isoquinoline alkaloids, derived from the plant Berberis. It is characterized by its tetrahydro structure, which indicates the presence of a saturated ring system. This compound exhibits a chiral nature, meaning it exists in two enantiomeric forms, which can have different biological activities. (±)-Tetrahydroberberine is known for its potential pharmacological properties, including anti-inflammatory, antioxidant, and neuroprotective effects. It has been studied for its role in metabolic regulation and may influence glucose metabolism and lipid profiles. The compound is typically found in a crystalline form and is soluble in organic solvents. Its molecular structure includes multiple functional groups that contribute to its reactivity and interaction with biological systems. As with many alkaloids, it may also exhibit varying degrees of toxicity and should be handled with care in laboratory settings. Overall, (±)-Tetrahydroberberine is of interest in both medicinal chemistry and pharmacology due to its diverse potential applications.

Formula: C₂₀H₂₁NO₄

InChI: InChI=1S/C20H21NO4/c1-22-17-4-3-12-7-16-14-9-19-18(24-11-25-19)8-13(14)5-6-21(16)10-15(12)20(17)23-2/h3-4,8-9,16H,5-7,10-11H2,1-2H3

InChI key: InChIKey=VZTUIEROBZXUFA-UHFFFAOYSA-N

SMILES: O(C)C1=C2CN3C(C=4C(=CC5=C(C4)OCO5)CC3)CC2=CC=C1OC

Synonyms:

• (±)-Tetrahydroberberine
• 5,8,13,13a-Tetrahydro-9,10-dimethoxy-6H-benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine
• 6H-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine, 5,8,13,13a-tetrahydro-9,10-dimethoxy-
• Berberine, 9-deoxy-16,17-dihydro-
• Berberine, tetrahydro-
• Berbine, 9,10-dimethoxy-2,3-(methylenedioxy)-
• Canadine
• NSC 36351
• NSC 94918
• Tetrahydroberineper
• Tetrahydroumbellatine
• Xanthopuccine
• dl-Canadine

Canadine

CAS: 522-97-4

Color and Shape: Neat

Ref: 61-FOR3085.00

6H-Benzo[g]-1,3-benzodioxolo[5,6-a]quinolizine,5,8,13,13a-tetrahydro-9,10-dimethoxy-

CAS: 522-97-4

Formula: C₂₀H₂₁NO₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 339.3850

Ref: IN-DA019FSV

Tetrahydroberberine

CAS: 522-97-4

Formula: C₂₀H₂₁NO₄

Molecular weight: 339.39

Ref: 7W-GY3857

Tetrahydroberberine

CAS: 522-97-4

Tetrahydroberberine

Purity: ≥95%

Molecular weight: 339.39g/mol

Ref: 54-BUP10460

Canadine

CAS: 522-97-4

Formula: C₂₀H₂₁NO₄

Molecular weight: 339.38

Ref: 7W-GP9040

Canadine

Controlled Product

CAS: 522-97-4

Formula: C₂₀H₂₁NO₄

Color and Shape: Neat

Molecular weight: 339.38

Ref: 86-MM3085.00

Tetrahydroberberine

CAS: 522-97-4

Formula: C₂₀H₂₁NO₄

Purity: 95%~99%

Molecular weight: 339.391

Ref: BP-BP1377

Tetrahydroberberine

CAS: 522-97-4

Tetrahydroberberine (Canadine) is an isoquinoline alkaloid isolated from corydalis tuber, has a micromolar affinity for dopamine D(2) receptors.

Formula: C₂₀H₂₁NO₄

Purity: 99.38% - 99.85%

Color and Shape: Solid

Molecular weight: 339.39

Ref: TM-T2874

Canadine

CAS: 522-97-4

Natural alkaloid

Formula: C₂₀H₂₁NO₄

Purity: ≥ 98.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 339.39

Ref: 5G-80378

Canadine

Controlled Product

CAS: 522-97-4

Applications Canadine is a protoberberine alkaloid which potently block functional KATP channels natively expressed on midbrain dopamine neurons. Canadine is used for treatment of degenerative diseases or conditions associated with KATP channel signaling.
References Duchowicz, P., et al.: Bioorg. Med. Chem., 14, 5876 (2006), Sun., et al.: Br. J. Pharmcol., 158, 1302 (2009), Deeb, O., et al.: Chem. Biol. Drug Des., 76, 255 (2010),

Formula: C₂₀H₂₁NO₄

Color and Shape: Neat

Molecular weight: 339.38

Ref: TR-C175175

Canadine

CAS: 522-97-4

Canadine is a natural compound that may have therapeutic potential for metabolic disorders and oral pathogens. Canadine has been shown to inhibit the production of malonic acid, which is a key metabolite in the citric acid cycle. Canadine also inhibits oxidative injury by preventing lipid peroxidation, and it has been shown to reduce hepatic steatosis in experimental models. Canadine can be used as an anti-inflammatory agent and has also been shown to suppress protein synthesis. Canadine may also be useful as a drug interaction controller because it protects against oxidative injury caused by other drugs. Canadine is not toxic to animals at doses up to 10 mg/kg body weight when administered orally.
CADINE: A natural compound that may have therapeutic potential for metabolic disorders and oral pathogens. CADINE has been shown to inhibit the production of malonic acid, which is a key metabolite in the citric acid cycle. CADINE also inhibits oxidative injury by preventing lipid peroxidation, and it

Formula: C₂₀H₂₁NO₄

Purity: Min. 98 Area-%

Color and Shape: Slightly Yellow Powder

Molecular weight: 339.39 g/mol

Ref: 3D-FC19659

TETRAHYDROBERBERINE

CAS: 522-97-4

Formula: C₂₀H₂₁NO₄

Purity: 98%

Molecular weight: 339.391

Ref: 10-F535725