CAS 52214-84-3
:Ciprofibrate
Description:
Ciprofibrate is a synthetic compound classified as a fibrate, primarily used in the management of dyslipidemia, particularly to lower triglyceride levels and increase high-density lipoprotein (HDL) cholesterol. Its chemical structure features a phenoxy group and a carboxylic acid moiety, contributing to its lipid-modulating properties. The substance is known for its ability to activate peroxisome proliferator-activated receptors (PPARs), which play a crucial role in lipid metabolism. Ciprofibrate is typically administered orally and is well-absorbed in the gastrointestinal tract. It exhibits a moderate half-life, allowing for once or twice daily dosing. The compound is generally well-tolerated, though potential side effects may include gastrointestinal disturbances and muscle-related issues. As with other fibrates, it is important to monitor liver function and muscle enzyme levels during treatment. Ciprofibrate is often used in conjunction with lifestyle modifications and other lipid-lowering agents to achieve optimal therapeutic outcomes in patients with elevated lipid levels.
Formula:C13H14Cl2O3
InChI:InChI=1/C13H14Cl2O3/c1-12(2,11(16)17)18-9-5-3-8(4-6-9)10-7-13(10,14)15/h3-6,10H,7H2,1-2H3,(H,16,17)
InChI key:InChIKey=KPSRODZRAIWAKH-UHFFFAOYSA-N
SMILES:ClC1(Cl)C(C1)C2=CC=C(OC(C(O)=O)(C)C)C=C2
Synonyms:- 2-(4-(2,2-Dichlorocyclopropyl)phenoxy)2-methylpropanoic acid
- 2-(p-(2,2-Dichlorocyclopropyl)phenoxy)-2-methylpropionic acid
- 2-[4-(2,2-Dichloro-cyclopropyl)-phenoxy]-2-methyl-propionic acid
- Brn 1984981
- Ccris 173
- Ciprofibrato
- Ciprofibrato [INN-Spanish]
- Ciprofibratum
- Ciprofibratum [INN-Latin]
- Ciprol
- Lipanor
- Modalim
- Propanoic acid, 2-(4-(2,2-dichlorocyclopropyl)phenoxy)-2-methyl-
- Unii-F8252Jgo9S
- Win 35833
- Ciprofibrate
- 2-(p-(2,2-dichlorocyclopropyl)phenoxy)-2-methylpropionicacid
- Cipml
- 2-[4-(2，2-Dichlom-cyclopropyl)phenoxy]-2-methy|propanoic acid
- 2-(4-(2,2-dichlorocyclopropyl)phenoxy)-2-methyl-propionicaci
- Ciprofibric acid
- 2-(4-(2,2-dichlorocyclopropyl)phenoxy)-2-methyl-propanoicaci
- 2-[P-(2,2-DICHLOROCYCLOPROPYL)-PHENOXY]-2-METHYLPROPANOIC ACID
- See more synonyms
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Found 17 products.
Ciprofibrate
CAS:Formula:C13H14Cl2O3Purity:>98.0%(GC)(T)Color and Shape:White to Light yellow powder to crystalMolecular weight:289.15CIPROFIBRATE CRS
CAS:<p>CIPROFIBRATE CRS</p>Formula:C13H14Cl2O3Color and Shape:Crystalline Powder. White. Whitish. Powder.Molecular weight:289.1545Ciprofibrate
CAS:CiprofibrateFormula:C13H14Cl2O3Purity:99.9%Color and Shape:WhiteMolecular weight:288.032Propanoic acid, 2-[4-(2,2-dichlorocyclopropyl)phenoxy]-2-methyl-
CAS:Formula:C13H14Cl2O3Purity:98%Color and Shape:SolidMolecular weight:289.15452-(4-(2,2-Dichlorocyclopropyl)Phenoxy)-2-Methylpropanoic Acid
CAS:<p>2-(4-(2,2-Dichlorocyclopropyl)Phenoxy)-2-Methylpropanoic Acid</p>Purity:98%Molecular weight:289.15g/molCiprofibrate
CAS:Formula:C13H14Cl2O3Purity:≥ 98.0%Color and Shape:White to light-yellow powder or crystalsMolecular weight:289.15Ciprofibrate
CAS:<p>Ciprofibrate (Win35833) is a fibrate derivative with antilipidemic activity.</p>Formula:C13H14Cl2O3Purity:99.63% - >99.99%Color and Shape:White Or Almost White Crystalline PowderMolecular weight:289.15Ciprofibrate
CAS:Controlled Product<p>Applications Ciprofibrate is a hypolipemic agent, related structurally to Clofibrate (C586910). Ciprofibrate is used as an antilipemic.<br>References Davison, C., et al.: Drug. Metab. Dispos., 3, 520 (1975), Arnold, A., et al.: J. Pharm. Sci., et al.: 68, 1557 (1979), Tuchman-Duplessis, H., et al.: Toxicology, 12, 1 (1979),<br></p>Formula:C13H14Cl2O3Color and Shape:WhiteMolecular weight:289.152-[4-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid
CAS:<p>2-[4-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropanoic acid (CGP) is a drug that blocks the nuclear receptor PPARγ. It has been shown to reduce cholesterol levels by inhibiting the synthesis of cholesterol, as well as reducing liver lesions in vivo. CGP also inhibits the growth of cancer cells through its ability to bind to DNA and regulate transcriptional activity. The response element for this compound is found in the promoter region of the gene encoding the growth factor-β1 (GF-β1), which is an important regulator of cell proliferation, differentiation, and apoptosis. CGP also inhibits peroxisome proliferator activator receptor α (PPARα) and γ (PPARγ). This inhibition leads to decreased expression of genes involved in lipid metabolism, such as acyl CoA synthase and fatty acid synthetase. CGP has also been shown to be carcinogenic in vivo</p>Formula:C13H14Cl2O3Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:289.15 g/molCiprofibrate - Bio-X ™
CAS:<p>Ciprofibrate is a fibrate drug that is used as a lipid-lowering agent. This drug reduces both LDL and VLDL cholesterol levels in the blood. Ciprofibrate works by reducing the production of triglycerides in the liver and increasing the removal of triglycerides from the blood. This drug is an agonist of peroxisome proliferator-activated receptor alpha.</p>Formula:C13H14Cl2O3Purity:Min. 98 Area-%Color and Shape:PowderMolecular weight:289.15 g/mol2-(4-(2,2-Dichlorocyclopropyl)phenoxy)-2-methylpropanoic acid
CAS:Formula:C13H14Cl2O3Purity:95.0%Color and Shape:Solid, White to slightly pale yellow powderMolecular weight:289.15
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