CAS 523-50-2

angelicin

Description:

Angelicin, with the CAS number 523-50-2, is a naturally occurring compound classified as a furanocoumarin. It is primarily derived from plants in the Apiaceae family, such as Angelica archangelica. This compound is characterized by its unique chemical structure, which includes a furan ring fused to a coumarin moiety. Angelicin exhibits a range of biological activities, including phototoxicity, which means it can cause skin reactions upon exposure to ultraviolet light. Additionally, it has been studied for its potential anti-cancer properties, as it may inhibit the growth of certain cancer cells. The substance is also known for its role in traditional herbal medicine, where it has been used for various therapeutic purposes. In terms of physical properties, angelicin is typically a colorless to pale yellow crystalline solid, and it is soluble in organic solvents but has limited solubility in water. Its reactivity and interactions with biological systems make it a subject of interest in pharmacological research.

Formula: C₁₁H₆O₃

InChI: InChI=1S/C11H6O3/c12-10-4-2-7-1-3-9-8(5-6-13-9)11(7)14-10/h1-6H

InChI key: InChIKey=XDROKJSWHURZGO-UHFFFAOYSA-N

SMILES: O=C1OC=2C3=C(C=CC2C=C1)OC=C3

Synonyms:

• 2-Oxo-(2H)-Furo(2,3-H)-1-Benzopyran
• 2-Propenoic acid, 3-(4-hydroxy-5-benzofuranyl)-, delta-lactone
• 2-Propenoic acid, 3-(4-hydroxy-5-benzofuranyl)-, δ-lactone
• 2H-Furo(2,3-H)-1-benzopyran-2-one
• 2H-furo[2,3-h]chromen-2-one
• 3-(4-Hydroxy-5-benzofuranyl)-2-propenoic acid gamma-lactone
• 4-Hydroxy-5-benzofuranacrylic acid gamma-lactone
• Angecin
• Angelicin (VAN)
• Angelicin (coumarin deriv)
• Angelicin (coumarin derivative)
• Brn 0153970
• Ccris 4276
• Furo(2,3-h)coumarin
• Furo(5',4':7,8)coumarin
• Furo[5′,4′:7,8]coumarin
• Hsdb 3554
• Isopsoralen
• Isopsoralene
• Nsc 404563
• Angelicin
• 5-19-04-00447 (Beilstein Handbook Reference)
• Angelicin
• ANGELICINE hplc
• Isopsoralen （Angelicin）
• 3-(4-hydroxy-5-benzofuranyl)-2-propenoicacidgamma-lactone
• angelicin(coumarinderiv)
• 3-(4-hydroxy-5-benzofuranyl)-2-propenoicacidelta-lactone
• isopsoralin
• ANGELICINE
• ISOBERGAPTEN
• 4-hydroxy-5-benzofuranacrylicacidgamma-lactone
• furo(5’,4’,7,8)coumarin

Angelicin

CAS: 523-50-2

Angelicin analytical standard provided with w/w absolute assay, to be used for quantitative titration.

Formula: C₁₁H₆O₃

Purity: (HPLC) ≥98%

Color and Shape: Powder

Molecular weight: 186

Ref: 11-0537S

Angelicin

CAS: 523-50-2

Angelicin

Formula: C₁₁H₆O₃

Purity: >98%

Molecular weight: 186.16

Ref: 54-OR1027422

2-Oxo-(2H)-furo(2,3-h)-1-benzopyran

CAS: 523-50-2

Formula: C₁₁H₆O₃

Purity: 98%

Color and Shape: Solid

Molecular weight: 186.1635

Ref: IN-DA00DEA6

Angelicin

CAS: 523-50-2

Angelicin

Formula: C₁₁H₆O₃

Purity: ≥98%

Color and Shape: Solid

Molecular weight: 186.16

Ref: 54-BUP00026

Angelicin

CAS: 523-50-2

Formula: C₁₁H₆O₃

Purity: ≥ 98.0%

Color and Shape: White to off-white powder

Molecular weight: 186.16

Ref: 7W-GP6228

Angelicin

CAS: 523-50-2

Angelicin is a furocoumarin found in Psoralea corylifolia L. fruit, can block the phosphorylation of IκBα, NFκBp65, p38 MAPK, and JNK in lipopolysaccharide-induced acute lung injury model, suggests that angelicin was potentially advantageous to prevent inflammatory diseases by inhibiting NF-κB and MAPK pathways, it might be a potential new agent for prevention of inflammatory reactions and diseases in the clinic.

Formula: C₁₁H₆O₃

Purity: 95%~99%

Color and Shape: Powder

Molecular weight: 186.166

Ref: BP-BP0171

Angelicin

CAS: 523-50-2

Formula: C₁₁H₆O₃

Purity: >98.0%(GC)

Color and Shape: White to Almost white powder to crystal

Molecular weight: 186.17

Ref: 3B-A2573

Angelicin

CAS: 523-50-2

2H-Furo[2,3-h]chromen-2-one

Formula: C₁₁H₆O₃

Purity: 98%

Molecular weight: 186.16

Ref: IN-DG77901

Angelicin

CAS: 523-50-2

Angelicin (Isopsoralen), is a furanocoumarin with anti-Y, antiviral, anti-inflammatory activity.

Formula: C₁₁H₆O₃

Purity: 99.86% - 99.89%

Color and Shape: Solid

Molecular weight: 186.16

Ref: TM-T2875

Angelicin

CAS: 523-50-2

Lactone

Formula: C₁₁H₆O₃

Purity: ≥ 98.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 186.17

Ref: 5G-89874

Angelicin

CAS: 523-50-2

Applications Antifungal.
References Sardari, S., et al.: Pharm. Pharmacol. Commun., 6, 455 (2000),

Formula: C₁₁H₆O₃

Color and Shape: Neat

Molecular weight: 186.16

Ref: TR-A637575

Angelicin

CAS: 523-50-2

Angelicin is a furanocoumarin compound, which is derived from various plant sources, particularly within the Apiaceae family. The source of angelicin is often linked to traditional medicinal plants, where it is extracted and subsequently isolated for scientific investigation. Angelicin's mode of action involves intercalating within DNA strands, thereby affecting transcription and replication processes. This action is understood to be primarily photoactivated, leading to the formation of covalent bonds with DNA upon exposure to ultraviolet light, which can result in cross-linking.

Formula: C₁₁H₆O₃

Purity: Min. 95%

Color and Shape: Powder

Molecular weight: 186.16 g/mol

Ref: 3D-FA17920

2H-Furo[2,3-h]chromen-2-one

CAS: 523-50-2

Formula: C₁₁H₆O₃

Purity: 98%

Molecular weight: 186.166

Ref: 10-F239136