CAS 524-14-1

Malonyl CoA

Description:

Malonyl CoA, or malonyl coenzyme A, is a crucial intermediate in various metabolic pathways, particularly in fatty acid synthesis and degradation. It is formed from acetyl CoA and bicarbonate in a reaction catalyzed by the enzyme acetyl-CoA carboxylase. This compound plays a significant role in regulating fatty acid metabolism, as it inhibits carnitine acyltransferase I, thereby preventing the transport of fatty acids into the mitochondria for β-oxidation. Structurally, malonyl CoA consists of a malonate group linked to coenzyme A, which contributes to its reactivity and function in biosynthetic pathways. It is a highly polar molecule, making it soluble in aqueous environments, which is essential for its role in cellular metabolism. Malonyl CoA is also involved in the synthesis of other biomolecules, including certain amino acids and polyketides. Its regulation is critical for maintaining energy homeostasis and lipid metabolism in cells. Overall, malonyl CoA is a vital metabolite with significant implications in biochemistry and cellular physiology.

Formula: C₂₄H₃₈N₇O₁₉P₃S

InChI: InChI=1S/C24H38N7O19P3S/c1-24(2,19(37)22(38)27-4-3-13(32)26-5-6-54-15(35)7-14(33)34)9-47-53(44,45)50-52(42,43)46-8-12-18(49-51(39,40)41)17(36)23(48-12)31-11-30-16-20(25)28-10-29-21(16)31/h10-12,17-19,23,36-37H,3-9H2,1-2H3,(H,26,32)(H,27,38)(H,33,34)(H,42,43)(H,44,45)(H2,25,28,29)(H2,39,40,41)/t12-,17-,18-,19+,23-/m1/s1

InChI key: InChIKey=LTYOQGRJFJAKNA-DVVLENMVSA-N

SMILES: O[C@H]1[C@H](N2C=3C(N=C2)=C(N)N=CN3)O[C@H](COP(OP(OCC([C@H](C(NCCC(NCCSC(CC(O)=O)=O)=O)=O)O)(C)C)(=O)O)(=O)O)[C@H]1OP(=O)(O)O

Synonyms:

• Malonyl CoA
• Malonyl coenzyme A
• Coenzyme A, S-(hydrogen malonate)
• Thiomalonic acid S-ester with coenzyme A
• Coenzyme A, S-(hydrogen propanedioate)

Malonyl CoA

CAS: 524-14-1

Malonyl CoA

Formula: C₂₄H₃₈N₇O₁₉P₃S

Purity: ≥90%

Molecular weight: 853.58

Ref: 54-OR1128625

Malonyl CoA

CAS: 524-14-1

Malonyl CoA: needed for fat creation, stops fat breakdown, reversibly inhibits CPT1 in mitochondria.

Formula: C₂₄H₃₈N₇O₁₉P₃S

Color and Shape: Solid

Molecular weight: 853.58

Ref: TM-T73829

Malonyl CoA

CAS: 524-14-1

Formula: C₂₄H₃₈N₇O₁₉P₃S

Purity: 90%

Color and Shape: Solid

Molecular weight: 853.5803

Ref: IN-DA00DDSU

Malonyl Coenzyme A, Free Acid

CAS: 524-14-1

Purity: 95%

Molecular weight: 853.116

Ref: 10-C300042