CAS 524-17-4

Dauricine

Description:

Dauricine, with the CAS number 524-17-4, is an alkaloid derived from various plant species, particularly those in the Menispermaceae family. It is known for its structural complexity, featuring a tetracyclic framework that contributes to its biological activity. Dauricine exhibits a range of pharmacological properties, including analgesic, anti-inflammatory, and potential antitumor effects, making it of interest in medicinal chemistry. The compound is typically found in the form of a white to pale yellow crystalline solid and is soluble in organic solvents like ethanol and chloroform, but less soluble in water. Its mechanism of action is thought to involve modulation of neurotransmitter systems and interference with cellular signaling pathways. Due to its bioactive nature, research continues into its therapeutic potential and safety profile, although further studies are necessary to fully understand its efficacy and mechanisms in various biological contexts. As with many alkaloids, caution is advised regarding its use, as it may exhibit toxicity at higher concentrations.

Formula: C₃₈H₄₄N₂O₆

InChI: InChI=1/C38H44N2O6/c1-39-15-13-26-20-35(42-3)37(44-5)22-29(26)31(39)17-24-7-10-28(11-8-24)46-34-19-25(9-12-33(34)41)18-32-30-23-38(45-6)36(43-4)21-27(30)14-16-40(32)2/h7-12,19-23,31-32,41H,13-18H2,1-6H3

InChI key: InChIKey=AQASRZOCERRGBL-ROJLCIKYSA-N

SMILES: C([C@@H]1C=2C(=CC(OC)=C(OC)C2)CCN1C)C3=CC(OC4=CC=C(C[C@@H]5C=6C(=CC(OC)=C(OC)C6)CCN5C)C=C4)=C(O)C=C3

Synonyms:

• 4-[(6,7-Dimethoxy-2-Methyl-1,2,3,4-Tetrahydroisoquinolin-1-Yl)Methyl]-2-{4-[(6,7-Dimethoxy-2-Methyl-1,2,3,4-Tetrahydroisoquinolin-1-Yl)Methyl]Phenoxy}Phenol
• 4-[[(1R)-1,2,3,4-Tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]-2-[4-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]phenoxy]phenol
• 4-{[(1R)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl}-2-(4-{[(1R)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl]methyl}phenoxy)phenol
• Nsc 36413
• Phenol, 4-((1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)methyl)-2-(4-((1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)methyl)phenoxy)-, (R-(R*,R*))-
• Phenol, 4-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]-2-[4-[[(1R)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl]methyl]phenoxy]-
• Dauricine
• 6,6'-Di-O-Methyldauricoline
• Menispermum dauricum DC Extract
• (r-(r*,r*))-y)
• -(4-((1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-isoquinolinyl)methyl)phenox
• dauricine (8ci)

Dauricine

CAS: 524-17-4

Formula: C₃₈H₄₄N₂O₆

Molecular weight: 624.77

Ref: 7W-GP0181

Dauricine

CAS: 524-17-4

Dauricine

Formula: C₃₈H₄₄N₂O₆

Purity: 99.5%

Molecular weight: 624.77

Ref: 54-BUP07831

Dauricine

CAS: 524-17-4

Formula: C₃₈H₄₄N₂O₆

Purity: 98%

Color and Shape: Solid

Molecular weight: 624.7658

Ref: IN-DA00DEJ0

Dauricine

CAS: 524-17-4

Formula: C₃₈H₄₄N₂O₆

Purity: 95%~99%

Molecular weight: 624.778

Ref: BP-BP0452

Dauricine (Standard)

CAS: 524-17-4

Dauricine (Standard) is a reference standard for research and analysis in studies involving Dauricine. 1. Dauricine has pulmonary toxicity, can produce pulmonary injury in CD-1 mice by the metabolism of Dauricine mediated by CYP3A. 2. Dauricinec can pass the blood-brain barrier, and that P-glycoprotein has an important role in the transportation of Dauricine across the blood-brain barrier. 3. Dauricine may has anti-tumor effect, can inhibit tumor cells in urinary system and colon cancer cell proliferation, invasion; induce cell apoptosis by suppressing NF-kappaB activity and the expression profile of its downstream genes.

Formula: C₃₈H₄₄N₂O₆

Molecular weight: 624.7658

Ref: TM-TMSM-0845

Dauricine

Controlled Product

CAS: 524-17-4

Applications Dauricine is a bisbenzylisoquinoline allkaloid derivative that displays a noted number of pharmaceutical properties. It is known to induces severe lung toxicity in animals.
References Xie, H. et al.: Anal. Bioanal. Chem., 408, 4111 (2016);

Formula: C₃₈H₄₄N₂O₆

Color and Shape: Neat

Molecular weight: 624.77

Ref: TR-D194825

Dauricine

CAS: 524-17-4

1.

Formula: C₃₈H₄₄N₂O₆

Purity: 99.24% - 99.75%

Color and Shape: Solid

Molecular weight: 624.7658

Ref: TM-T6S0119

Dauricine

CAS: 524-17-4

Natural alkaloid

Formula: C₃₈H₄₄N₂O₆

Purity: ≥ 90.0 % (HPLC)

Color and Shape: Powder

Molecular weight: 624.78

Ref: 5G-80419

Dauricine

CAS: 524-17-4

Dauricine is a natural bisbenzylisoquinoline alkaloid, which is derived from the plant Menispermum dauricum, commonly found in regions of Asia. Its mode of action involves inhibition of various ion channels, notably the calcium and potassium channels, as well as modulation of signaling pathways that influence cell proliferation and apoptosis. These biochemical activities endow Dauricine with the potential to influence cardiovascular, neurological, and oncological outcomes.

Formula: C₃₈H₄₄N₂O₆

Purity: Min. 95%

Color and Shape: Brown Yellow Powder

Molecular weight: 624.77 g/mol

Ref: 3D-FD66056

Dauricine

CAS: 524-17-4

Formula: C₃₈H₄₄N₂O₆

Molecular weight: 624.8

Ref: BE-RMT10620

Dauricine

CAS: 524-17-4

4-(((R)-6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl)-2-(4-(((R)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl)phenoxy)phenol

Formula: C₃₈H₄₄N₂O₆

Purity: 98%

Molecular weight: 624.77

Ref: IN-DG123496

DAURICINE

CAS: 524-17-4

Purity: 98%

Molecular weight: 624.7780151

Ref: 10-F794658