CAS 52450-18-7

3'-amino-3'-deoxythymidine

Description:

3'-Amino-3'-deoxythymidine, also known as amido-3'-deoxythymidine, is a nucleoside analog of thymidine, characterized by the presence of an amino group at the 3' position of the sugar moiety. This modification alters its biological properties, making it of interest in medicinal chemistry, particularly in antiviral and anticancer research. The compound retains the thymine base, which is essential for its role in nucleic acid synthesis. Its structure allows it to potentially interfere with DNA replication and repair processes, making it a candidate for therapeutic applications. The presence of the amino group enhances its solubility and may influence its interaction with enzymes involved in nucleic acid metabolism. Additionally, 3'-amino-3'-deoxythymidine has been studied for its potential to inhibit viral replication, particularly in the context of retroviruses. As with many nucleoside analogs, its efficacy and safety profile are subjects of ongoing research, and understanding its pharmacokinetics and mechanism of action is crucial for its development as a therapeutic agent.

Formula: C₁₀H₁₅N₃O₄

InChI: InChI=1/C10H15N3O4/c1-5-3-13(10(16)12-9(5)15)8-2-6(11)7(4-14)17-8/h3,6-8,14H,2,4,11H2,1H3,(H,12,15,16)/t6-,7+,8+/m0/s1

Synonyms:

• 3'-Aminothymidine
• Thymidine, 3'-amino-3'-deoxy-
• 3'-Amino-2',3'-dideoxythymidine
• 3'-NH2-ddT
• 1-[(2R,4S,5S)-4-Amino-5-(Hydroxymethyl)Oxolan-2-Yl]-5-Methylpyrimidine-2,4-Dione

3'-Amino-2',3'-dideoxythymidine, 99%

CAS: 52450-18-7

This Thermo Scientific Chemicals brand product was originally part of the Alfa Aesar product portfolio. Some documentation and label information may refer to the legacy brand. The original Alfa Aesar product / item code or SKU reference has not changed as a part of the brand transition to Thermo Sci

Formula: C₁₀H₁₅N₃O₄

Purity: 99%

Molecular weight: 241.24

Ref: 02-J64342

Thymidine, 3'-amino-3'-deoxy-

CAS: 52450-18-7

Formula: C₁₀H₁₅N₃O₄

Purity: 98%

Color and Shape: Solid

Molecular weight: 241.2438

Ref: IN-DA00I9DU

3''-Amino-3''-deoxythymidine

CAS: 52450-18-7

Formula: C₁₀H₁₅N₃O₄

Purity: (HPLC) ≥ 98.0%

Color and Shape: White to yellow crystalline powder

Molecular weight: 241.24

Ref: 7W-GN3308

1-((2R,4S,5S)-4-Amino-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

CAS: 52450-18-7

1-((2R,4S,5S)-4-Amino-5-(hydroxymethyl)tetrahydrofuran-2-yl)-5-methylpyrimidine-2,4(1H,3H)-dione

Purity: 98%

Molecular weight: 241.25g/mol

Ref: 54-OR1062886

3'-Amino-3'-deoxythymidine

CAS: 52450-18-7

Formula: C₁₀H₁₅N₃O₄

Molecular weight: 241.25

Ref: 4Z-T-589

3’-Amino-3’-deoxythymidine

Controlled Product

CAS: 52450-18-7

Impurity Zidovudine Impurity;
Stability Hygroscopic, Moisture Sensitive
Applications A metabolite of Zidovudine (3'-Azido-3'-deoxythymidine; AZT).
References Qian, M., et al.: Biochem. Pharmacol., 48, 383 (1994), Diwan, B., et al.: Toxicol. Appl. Pharmacol., 161, 82 (1999) , Lim, S., et al.: J. Biol. Chem., 276, 23616 (2001), Von Tungeln, L., et al.: Carcinogenesis, 23, 1427 (2002),

Formula: C₁₀H₁₅N₃O₄

Color and Shape: White To Off-White

Molecular weight: 241.24

Ref: TR-A604250

3’-Amino-3’-deoxythymidine

CAS: 52450-18-7

Formula: C₁₀H₁₅N₃O₄

Molecular weight: 241.25

Ref: ST-EA-CP-Z6009

3'-Amino-3'-deoxythymidine

CAS: 52450-18-7

Also known as AMT, this is a catabolite of the nucleoside analog zidovudine (AZT), a drug used to treat HIV infection.

Formula: C₁₀H₁₅N₃O₄

Purity: Min. 98 Area-%

Color and Shape: Powder

Molecular weight: 241.24 g/mol

Ref: 3D-NA02831

3′-AMINO-2′,3′-DIDEOXYTHYMIDINE

CAS: 52450-18-7

Formula: C₁₀H₁₅N₃O₄

Purity: 98%

Molecular weight: 241.247

Ref: 10-F334250